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All Journal Jurnal Online Mahasiswa (JOM) Bidang Kedokteran Ina Kidney
Ade Novita Reslina, Ade Novita
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Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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GAMBARAN RASIO NEUTROFIL IMATUR/NEUTROFIL TOTAL (RASIO I/T) PADA TERSANGKA SEPSIS NEONATORUM YANG DIRAWAT DI INSTALASI PERAWATAN NEONATUS RSUD ARIFIN ACHMAD PROVINSI RIAU Reslina, Ade Novita; ", Fatmawati; Wisnumurti, Dewi A
Jurnal Online Mahasiswa (JOM) Bidang Kedokteran Vol 2, No 2 (2015): Wisuda Oktober 2015
Publisher : Jurnal Online Mahasiswa (JOM) Bidang Kedokteran

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ABSTRACTBackground: Neonatal sepsis is one of major cause of neonatal death in developing countries. Blood culture is gold standard to diagnose sepsis neonatorum, but it needed 3-5 days for the result. Early diagnostic and approriate treatment can reduce the mortality and morbidity of patients. Immature to total neutrophil ratio (I/T ratio) can be used as early marker for diagnosis of neonatal sepsis.Objective: This study aimed to know I/T ratio of suspected neonatal sepsis treated in the Neonatal Unit of Arifin Achmad General Hospital of Riau Province.Methods: This is study was conducted using descriptive retrospective methods during February 2015. The sample were collected by consecutive sampling. Results: We found that 97 suspected neonatal sepsis, 81,5% of whom were 0-6 days old, 56,7% were males, and 48,5% had gestational age < 37 weeks. Late onset sepsis was the highest classification of sepsis at 80% from 30 cases of neonatal sepsis. Immature to total neutrophil ratio on suspected neonatal sepsis was ≥ 0,2 (50,5%) with a median value is 0,2.Conclusion: There was a increased I/T ratio on suspected neonatal sepsis.Keywords: sepsis, neonate, I/T ratio
Acute Kidney Injury Incidence in COVID-19 Patients Receiving Remdesivir Therapy at Awal Bros Panam Hospital Reslina, Ade Novita; Monita, Faradilla; Sembiring, Ligat Pribadi
Indonesian Journal of Kidney and Hypertension Vol 1 No 2 (2024): Volume 1 No. 2, August 2024
Publisher : PERNEFRI (PERHIMPUNAN NEFROLOGI INDONESIA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32867/inakidney.v1i2.127

Abstract

Background: Remdesivir is one of the pharmacological therapies for moderate COVID-19 patients. Remdesivir is an antiviral that can increase the risk of nephrotoxicity. Objective: The study aims to evaluate the incidence of acute kidney injury (AKI) in COVID-19 patients receiving remdesivir. Methods: This is a cross-sectional analytic study of 238 COVID-19 patients receiving remdesivir therapy at Awal Bros Panam Hospital for the period 2020–2022. AKI was diagnosed using the KDIGO criteria. The chi-square test was used to determine the correlation of AKI incidence with age, gender, and comorbidities, with a significance level of p < 0.05. Results: AKI was found in 32 patients (13.4%). The majority of AKI patients (75%) were aged 60 years or older, with 65.6% being male. Additionally, 84.4% of these patients had comorbidities, and 53.1% of them died. Around half of the patients were diagnosed with stage 1 AKI, and the majority, specifically 84.4%, did not undergo renal replacement therapy (RRT). The association between the incidence of AKI and age and comorbidities was shown to be statistically significant (p=0.000; RR 5.11; 95% CI 2.44-10.8 and p=0.009; RR 3.05; 95% CI 1.22-7.64, respectively). Conclusion: The main risk factors for AKI are primarily observed in the older population and individuals with several medical conditions. Greater emphasis should be placed on administering remdesivir to COVID-19 patients who are elderly and have comorbidities, as they are at a higher risk of developing AKI.
Co-Authors Dewi A Wisnumurti, Dewi A Faradilla Monita, Faradilla Fatmawati " Ligat Pribadi Sembiring