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Deborah Melati, Deborah
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Medicine & Pharmacology

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FIRST UNPROVOKED SEIZURE PADA ANAK Melati, Deborah; Suwarba, IGN Made; Sutriani M, Dewi; Kari, Komang
Medicina Vol 45 No 2 (2014): Mei 2014
Publisher : Medicina

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Abstract

Kejang sangat sering ditemukan pada pasien anak dengan perkiraan kejadian first unprovoked seizuresebesar 2% dan epilepsisebesar 1% pada anak sebelum berusia 16 tahun. First unprovoked seizure adalah kejang yang terjadi tanpa faktor pencetus seperti demam, infeksi sistem saraf pusat, trauma kepala, gangguan metabolik, hipoksia otak, dan obat-obatan.Berulangnya first unprovoked seizure berbeda-beda pada setiap pasien dan dipengaruhi oleh faktor risiko perorangan seperti gambaran EEG epileptiform atau adanya kelainan neurologis sebelumnya.Tatalaksana first unprovoked seizure berupa mengatasi kejang pada saat serangan.Pemberian obat anti-epilepsi pada pasien dengan first unprovoked seizure masih kontroversial.Tujuan utama pemberian obat anti-epilepsi pada pasien dengan first unprovoked seizure adalah mengoptimalisasi kualitas hidup anak dengan mempertimbangkan risiko pemberian obat dan mencegah berulangnya kejang, pemilihan keluarga serta efek samping pemberian obat. [MEDICINA. 2014;45:93-8].    
HENOCH SCHONLEIN PURPURA ASSOCIATED WITH ACUTE POSTSTREPTOCOCCAL GLOMERULONEPHRITIS: A CASE REPORT Melati, Deborah; Kumara Wati, Ketut Dewi; Putu Nilawati, Gusti Ayu
Medicina Vol 45 No 2 (2014): Mei 2014
Publisher : Medicina

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Abstract

Acute post-streptococcal glomerulonephritis (APSGN) is one of the most common renal disease resulting from a prior infection with group A â-hemolytic streptococcus (GAS). Henoch Schonlein Purpura (HSP) is a systemic disease with frequent renal involvement, its etiology is still unknown but several infections have been described as trigger includingGAS infection. A 4 year 10 month old Balinese boy presented with full blown acute nephritic syndrome, an elevation in serum creatinine and four fold increase of anti streptolysin-O, also low serum levels of complement C3 with normal C4 confirmed the diagnosis of APSGN. During hospitalization he developed palpable purpura, gastrointestinal symptoms as well as leucytoclastic vasculitis in skin biopsy conclude HSP diagnosis.He was treated with anti-hypertensions and metylprednisolone intravenous. The prognosis of the patient was excellent, he showed normal physical examination with normal complete blood count and urinalysis after 3 months follow up. We conclude that both APSGN and HSP could appear concurrently after GAS infection. [MEDICINA 2014;45:102-7]  
Co-Authors Dewi Sutriani Mahalini Gusti Ayu Putu Nilawati I Gusti Ngurah Made Suwarba Ketut Dewi Kumara Wati Komang Kari