M. Umar Riandi, M. Umar
National Institute of Health and Research and Development, Ministry of Health of Republic of Indonesia

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Infeksi Virus Dengue Tanpa Gejala pada Keluarga Penderita DBD di Provinsi Jawa Barat Santya, Roy NRE; Riandi, M. Umar
Jurnal Biotek Medisiana Indonesia Vol 1, No 2 (2012)
Publisher : Central Basic Biomedical and Health Technology

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Abstract

Dengue Hemorrhagic Fever (DHF) in Indonesia shows an increasing trend since it was first reported in 1968. Based on data from 2003 to 2007, all districts in West Java province had reported outbreak of DHF. Dengue virus transmission is kept up by the presence of virus in the infective host in human and/or mosquitoes. A cross-sectional research was conducted to obtain the incidence of asymptomatic dengue infections in family members of the individual infected. Data was extracted from respondents who were family members of patients that showed immunological response to dengue virus infection. Out of 979 family members of patients tested, 183 (18.7%) individual showed asymptomatic positive immunological response of dengue virus infection. Respondents who leave in a district have risk to be infected 1.35 fold greater than those who leave in a city (p= 0,043; 95% CI =1,004-1,805). There is no significant risk to be infected among gender (female and male respondent) and age groups (≤ 15 years and > 15 years).There is a latent potential problem of sustainable dengue virus transmission in West Java Province. This condition requires attention because the existence of positive individuals without symptoms and their mobility play a role as a reservoir of dengue virus.Key words: dengue virus infection, asymptomatic, immunological responses AbstrakDemam Berdarah Dengue di Indonesia menunjukkan tren meningkat sejak dilaporkan sejak tahun 1968. Berdasarkan data tahun 2003-2007 seluruh Kabupaten di Jawa Barat melaporkan adanya KLB DBD. Transmisi virus dengue terus ada karena ada penularan virus antar manusia melalui nyamuk. Penelitian ini adalah Cross seksional yang dilakukan untuk mengetahui adanya insidens dengue tanpa gejala diantara anggota keluarga dari orang yang terinfeksi. Data diperoleh dari responden yang merupakan keluarga dari responden yang menunjukkan adanya respon imun terhadap virus dengue. Dari 979 anggota keluarga yang di test sebanyak 183 (18,7%) menunjukkan adanya respon imun terhadap virus dengue. Responden yang tinggal di kabupaten yang mempunyai risiko terinfeksi sebesar 1,35 lebih tinggi dari pada yang tinggal di dalam kota (p= 0,043; 95% CI = 1,004-1,805). Tidak ada risiko terinfeksi antara gender, kelompok umur (<15 tahun dan >15 tahun) yang signifikan. Terdapat problem laten untuk transmisi virus dengue yang terus menerus di Jawa Barat. Kondisi ini membutuhkan perhatian karena keberadaan individu tanpa gejala dan mobilitasnya berperan sebagai resevoa virus dengue.Kata kunci: Infeksi virus dengie, asymptomatic, respon imun
STUDY OF HERBAL TOPICAL REPELLENT MADE OF BETEL LEAVES (Piper betle) AND PATCHOULI OIL (Pogostemon cablin) MIXTURE AGAINST YELLOW FEVER MOSQUITO (Aedes aegypti) Widawati, Mutiara; Riandi, M. Umar
BIOTROPIA Vol. 22 No. 1 (2015): BIOTROPIA Vol. 22 No. 1 June 2015
Publisher : SEAMEO BIOTROP

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (715.731 KB) | DOI: 10.11598/btb.2015.22.1.378

Abstract

Exploration of plants as natural repellent against yellow fever mosquito (Aedes aegypty) that transmits dengue virus to human is still underway. Betel leaves (Piper betle) could be used as repellent material. The study was aimed to test the repellency, potency, and safety of topical lotion repellent of betel and patchouli oil mixture against yellow fever mosquito. This study used nulliparous of 3-5 days old female yellow fever mosquito. Before the study, irritation test was conducted as safety test. Five treatments with five replications was implemented to seek the most effective repellent substance i.e. DEET lotion for positive control, betel leaves and patchouli oil mixture lotion, betel leaves only lotion, patchouli oil only lotion and base lotion only. The substance effectiveness was determined based on the rejection of yellow fever mosquito to bite human's arms and was analyzed using protective percentage. The irritation test showed no safety concerns. Protective percentage analysis showed that modified betel leaves lotion had mean protective power of over 900/0 for 6 hours. The data showed that the modified lotions had the same protective percentage as the DEET (ratio: PP (betel+patchou1i)/PP (DEET) =O.98; confidence interval 0.93, 1.04; p- value=O.50). This indicated that betel leaves mixed with patchouli oil is potential to be used as safe repellent against yellow fever mosquito.