Suratman Suratman
Department Of Public Health, Faculty Of Health Sciences, Jenderal Soedirman University, Purwokerto 53123, Indonesia

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A Correlation Study : Levels of Butyrylcholinesterase and Paraoxonase 1 Activity amongst Shallot Farmworkers in Brebes Regency, Central Java, Indonesia Suratman Suratman; Kuswanto Kuswanto; Agnes Fitria Widiyanto
JURNAL KESEHATAN LINGKUNGAN Vol. 11 No. 4 (2019): JURNAL KESEHATAN LINGKUNGAN
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jkl.v11i4.2019.354-360

Abstract

Organophosphate insecticides (OPs) are one of the pesticides commonly used in agricultural activities either to eradicate or to protect crops from insect attacks. Aside from the advantages proposed, this OPs substance also brings some worrisome threats for individual and population. Shallot farmworkers in Brebes Regency are population at risk to OPs exposure. The activity levels of Butyrylcholinesterase (BuChE) and paraoxonase 1 (PON1) in blood play important roles as a biomarker of exposure as well to measure the occurrence of OPs exposure in a human body and as a biomarker of susceptibility as well to measure the level of detoxifying OPs. The aim of this study was to analyse the correlation between levels of BuChE and PON1 activities amongst shallot farmworkers. A cross-sectional study was conducted on 88 male subjects selected randomly from Dukuhlo Village in Brebes Regency, Indonesia, occupationally exposed to OPs from April to May 2017. Using a structured questionnaire, a survey was carried out based on sociodemographic characteristics. Blood samples were collected to determine the levels of BuChE and PON1 activity. These samples were then analysed at laboratories of Cito in Tegal and Gaky, Undip in Semarang. Furthermore, data were analysed systematically using univariate and bivariate (a Spearman's Rank test). A significant correlation was found between these both variables (p=0.025 and rho=0.238) with slightly moderate positive relationship. To sum up, farmworkers with higher PON1 activity may have a better chance of detoxifying the acute effect of OPs exposure. A further research is needed to identify correlation between PON1 activity, levels of thyroid hormones, and OPs metabolites in urine.
Pesticides Exposure and Thyroid Hormone Levels Among Agricultural Workers and Pesticide Applicators: A Systematic Review Suratman Suratman; Suhartono Suhartono
JURNAL KESEHATAN LINGKUNGAN Vol. 14 No. 3 (2022): JURNAL KESEHATAN LINGKUNGAN
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jkl.v14i3.2022.178-192

Abstract

Introduction: Presently, the global consumption of pesticides including insecticides, herbicides, and fungicides to protect crops is increasing. Pesticides' role as Endocrine-Disrupting Chemicals (EDCs) has gained great concern in the field of thyroid hormones. Therefore, this systematic review aimed to determine the link of pesticide exposure with thyroid hormone levels among male agricultural workers and pesticide applicators. Discussion: It was discovered that the majority of reviewed articles have similar results concerning the effects of pesticide exposure on the serum levels of thyroid hormones among either farmworkers or pesticide applicators. Commonly, insecticides, herbicides, and fungicides are known as one of the EDCs. The results showed the elevation of TSH and T4 serum levels mostly occurred among groups exposed to insecticide application only rather than those exposed to various pesticide types. Moreover, the hormonal change differed based on each class of pesticide. Conclusion: This review suggests that some types of pesticides extensively used in agriculture might be involved in the increase and decrease in thyroid hormone levels among exposed individuals. Further studies should assess specific types of pesticides and the adverse health effects which involve confounding factors to yield robust analysis.
Analisis Pengelolaan Limbah Medis Padat di Puskesmas Kampung Laut Kabupaten Cilacap Jawa Tengah Santo Purwo; Edy Suyanto; Suratman Suratman
Cerdika: Jurnal Ilmiah Indonesia Vol. 2 No. 7 (2022): Cerdika: Jurnal Ilmiah Indonesia
Publisher : Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (741.022 KB) | DOI: 10.59141/cerdika.v2i7.410

Abstract

Timbulan limbah medis padat yang dihasilkan dari penanganan pelayanan kesehatan makin hari makin meningkat, ditambah lagi dengan upaya penanggulangan pandemi Corona Virus Disease 2019(Covid-19). Puskesmas Kampung Laut sebagai fasilitas pelayanan kesehatan pertama yang berada di perairan segara anakan wilayah Kabupaten Cilacap, membutuhkan metode pengelolaan limbah medis padat yang baik mulai dari pemilahan sampai pengangkutan. Penyimpanan dan pengangkutan limbah menjadi perhatian serius, limbah Bahan berbahaya beracun(B3) dikumpulkan sebulan sekali dan diangkut melalui perairan dengan perahu menimbulkan risiko kesehatan dan lingkungan yaitu risiko limbah di tempat penyimpanan sementara(TPS) B3, risiko tertusuk jarum atau benda tajam dan terkontaminasi jika tumpah selama pengangkutan. Tujuan penelitian adalah menganalisis pengelolaan limbah medis padat di Puskesmas dari berbagai aspek 1) input, 2) proses, 3) output, 4) strategi pengelolaan limbah medis padat di Puskesmas Kampung Laut, Kabupaten Cilacap. Metode penelitian adalah penelitian Kualitatif menggunakan pendekatan deskriptif, analisis data mengikuti konsep Miles dan Huberman dalam Moleong. Hasilnya di Puskesmas Kampung Laut upaya pengelolaan limbah medis padat sudah dilakukan, namun belum menunjukkan pengelolaan yang baik. Dilihat dari inputnya kekurangan SDM dan perencanaan anggaran, dari segi proses, standar operasional prosedur (SOP) belum dilaksanakan dengan baik, penyimpanan dan pengangkutan menjadi permasalahan dikarenakan kondisi geografis. Output pengelolaan limbah terkendala dan belum maksimal dalam pengelolaan limbah medis padat. Saran penelitian adalah merencanakan dan mengusulkan anggaran yang komprehensif untuk memenuhi kebutuhan pengelolaan limbah, pengadaan cold storage, teknik pengemasan dan transportasi untuk mengurangi risiko, komitmen penerapan SOP dan pemantauan evaluasi berkelanjutan untuk peningkatan pengelolaan limbah medis padat Puskesmas Kampung Laut Kabupaten Cilacap.