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Efek Antiinflamasi dan Antipiretik Ekstrak Batang Bajakah Tampala (Spatholobus littoralis Hassk) pada Mencit (Mus musculus L.) nofri - zayani; Bela Novita Amaris Susanto; Eva Marsepa
Jurnal Ilmiah Biosaintropis (Bioscience -Tropic) Vol 8 No 1 (2022): Agustus 2022
Publisher : Fakultas Matematika & Ilmu Pengetahuan Alam - Universitas Islam Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (557.813 KB) | DOI: 10.33474/e-jbst.v8i1.491

Abstract

Exploration of the plants used to treat inflammation and fever continues to grow. One of the plants with great potential is Bajakah tampala (Spatholobus littoralis Hassk). Phytochemical test results showed bajakah contains flavonoids, tannins, saponins, phenolics, and terpenoids that function as anti-inflammatory and antipyretic so as to reduce inflammation and fever. The purpose of this study was to examine the anti-inflammatory effect of Bajakah stem extract (EBB) on the edema area and leukocyte numbers, as well as its antipyretic effect on the rectal temperature of mices. Total experimental study design with a completely randomized factorial design consisted of 5 treatments (EBB doses 0, 25, 50, 100 and aspirin 80 mg/kg) and 4 replications. EBB was extracted by maceration with 70% ethanol. Mices used were 20 healthy males, aged 13-14 weeks, and weighed 30-35 grams. 1% carrageenan was used to induce inflammation and baker's yeast was used to induce fever. EBB is given orally after 30 minutes of inflammation and an increase in rectal temperature. Data were analyzed by variance analysis (ANOVA) and continued with Duncan Multiple Range Test (DMRT) at 1% level. The results showed that EBB administration had an effect on reducing edema area and leukocyte numbers after 1% carrageenan induced, and the rectal temperature of mices after baker's yeast induced. In conclusion, EBB has good anti-inflammatory and antipyretic effects with the most effective dose of 25 mg/kg. Keywords: Bajakah tampala, Edema, Leukocytes, Rectal temperature
TINGKAT PENGETAHUAN DAN SIKAP PERAWAT DENGAN TINDAKAN PENCEGAHAN INFEKSI LUKA OPERASI DI RUANG RAWAT BEDAH RSU KABUPATEN TANGERANG eva marsepa; endra gunawan; uang musaeri
Jurnal Kesehatan Vol 8 No 1 (2019): Jurnal Kesehatan
Publisher : Universitas Yatsi Madani

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Abstract

Background : infection of the surgical wound is a nosocomial infection that will result in losses, especially for patients and health service providers. Nurses as implementers of health services that interact with patients for about 8 hours a day, potentially as a determining factor in the prevention of nosocomial infections, especially surgical wound infection. Research Objectives: to know the relation between knowledge level and attitude of nurse with prevention of surgical wound infection in surgical ward of Tangerang General Hospital. Research Method: correlative descriptive research with cross sectional approach. The sample of this research is all the nurses in surgical ward of Tangerang General Hospital as much as 45 samples by using total sample (total sampling). Data of knowledge and attitude were obtained by using validated and reliable questionnaires while prevention of wound infection was obtained based on observation. Data analysis used univariate and for bivariate with chi-square test. Results : of the 45 implementing nurses most of whom were 27 (60%) knowledgeable about prevention of surgical wound infection, 25 (55,6%) were positive (supportive) prevention of surgical wound infections, 30 (66, 7%) with good category to prevention of surgical wound infection. There is a correlation of knowledge with prevention of surgical wound infection with p value 0,023 (< alpha = 0,05). There is relation of attitude with prevention of surgical wound infection with p value 0,015 (< alpha = 0,05). Conclusions And Suggestions: there is relation of knowledge and attitude with prevention surgical wound infection. Hospital is expected to improve the knowledge and attitude of nurses and other officers in preventing nosocomial infection by involving several staff / nurses regularly to attend seminar, symposium, or training on prevention of nosocomial infection especially prevention of surgical wound infection.