Garuda - Garba Rujukan Digital

An Overview of Diabetes Mellitus Type I Yulisnawati Hasanah
Arkus Vol. 4 No. 1 (2018): ARKUS
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/arkus.v4i1.73

Diabetes mellitus (DM) is a complex metabolic disorder characterized by the condition of persistent hyperglycemia due to abnormalities in insulin secretion, insulin action, or both. DM type 1 is more often often found in children but with increasing obesity rates, the number of children with type 2 diabetes is increasing. In children who have been diagnosed, determining the type of DM becomes important because of its large clinical implications especially for the choice of therapy. The determination of the type of DM is based on the clinical characteristics of the patient, but differentiating the various types is not always easy and is still a challenge in itself. DM management aims to achieve controlled glucose levels and prevent complications, both acute or chronic complications. Complications related to metabolic control and duration of suffering from DM, so early detection of DM especially in high-risk children should be sought as part of the prevention of DM and its various complications.

Diabetes Pada Anak Yulisnawati Hasanah
Conferences of Medical Sciences Dies Natalis Vol. 1 No. 1 (2019): Conferences of Medical Sciences Dies Natalis Faculty of Medicine Universitas Sr
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (661.254 KB)

Diabetes mellitus (DM) is a complex metabolic disorder characterized by the condition of persistent hyperglycemia due to abnormalities in insulin secretion, insulin action, or both. DM type 1 is more often often found in children but with increasing obesity rates, the number of children with type 2 diabetes is increasing. In children who have been diagnosed, determining the type of DM becomes important because of its large clinical implications especially for the choice of therapy. The determination of the type of DM is based on the clinical characteristics of the patient, but differentiating the various types is not always easy and is still a challenge in itself. DM management aims to achieve controlled glucose levels and prevent complications, both acute or chronic complications. Complications related to metabolic control and duration of suffering from DM, so early detection of DM especially in high-risk children should be sought as part of the prevention of DM and its various complications.

Diabetes Pada Anak Yulisnawati Hasanah
Conferences of Medical Sciences Dies Natalis Vol. 1 No. 1 (2019): Conferences of Medical Sciences Dies Natalis Faculty of Medicine Universitas Sr
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (842.512 KB)

Diabetes mellitus (DM) is a complex metabolic disorder characterized by the condition of persistent hyperglycemia due to abnormalities in insulin secretion, insulin action, or both. DM type 1 is more often often found in children but with increasing obesity rates, the number of children with type 2 diabetes is increasing. In children who have been diagnosed, determining the type of DM becomes important because of its large clinical implications especially for the choice of therapy. The determination of the type of DM is based on the clinical characteristics of the patient, but differentiating the various types is not always easy and is still a challenge in itself. DM management aims to achieve controlled glucose levels and prevent complications, both acute or chronic complications. Complications related to metabolic control and duration of suffering from DM, so early detection of DM especially in high-risk children should be sought as part of the prevention of DM and its various complications.

Cognitive function in Indonesian children with type 1 diabetes mellitus Ulfa, Marselya; Aditiawati, Aditiawati; Hasanah, Yulisnawati; Dhaini, Shafri; Bakrie, Achirul; Indra, Raden Muhammad
Paediatrica Indonesiana Vol. 64 No. 1 (2024): January 2024
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi64.1.2024.44-50

Background Children with type 1 diabetes mellitus (T1DM) are at risk of cognitive impairment. While the pathophysiology is still unclear, cognitive impairment in children with T1DM can result in significant negative effects on quality of life. Objective to evaluate the cognitive function of Indonesian children with T1DM and its association with glycemic control and to identify factors affecting cognitive function in children with T1DM. Methods The cognitive function of children aged 6 years or older with T1DM was measured using the Wechsler Intelligence Scale for Children-Revised (WISC-R). We analyzed for potential associations between cognitive function and glycemic control based on mean HbA1c levels and other factors, such as the age of onset, duration of illness, and maternal educational attainment. We also identified failure to achieve age-appropriate results on any of the WISC-R subtests (cognitive impairment) and associated factors. Results A total of 46 subjects were included in this study, with a mean age of 12.8 (SD 3.4) years. There were 27 (58.7%) girls and 19 (41.3%) boys. Subjects’ mean full-scale IQ (FSIQ) was 91.35 (SD 11.43). A moderate negative correlation was found between FSIQ and mean HbA1c levels (r=-0.43; P<0.01). Children with mothers who had university degrees had significantly higher IQs (mean difference 7.39; 95%CI 3.10 to 13.66; P=0.02) than those with mothers without degrees. Failure of any WISC-R subtest was noted in 34 subjects, consisting of 17 verbal, 1 performance, and 34 verbal and performance subtests. A higher proportion of those with cognitive impairment had mean HbA1c >10%. However, compared to those with mean HbA1c ?10, the difference did not reach a statistical significance (OR 5.0; 95%CI 0.95 to 26.31; P=0.50) Conclusion Glycemic control and maternal educational attainment are associated with cognitive function in Indonesian children with T1DM. Poor glycemic control is also associated with a higher risk of cognitive impairment.

Nerve conduction parameters in children with severe acute malnutrition treated with standard nutritional therapy Khalid, Naman; Dewi, Msy Rita; Indra, RM; Anzar, Julius; Nova, Ria; Indrayadi, Indrayadi; Hasanah, Yulisnawati; Fauzi, Moretta Damayanti
Paediatrica Indonesiana Vol. 65 No. 1 (2025): January 2025
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi65.1.2025.54-60

Background Nerve damage has been found in malnourished patients due to deficiencies in micronutrients and macronutrients. Studies on nerve conduction in malnourished children are scarce, specifically those comparing nerve conduction parameters before and after nutritional intervention, are few. Objective To identify nerve conduction changes in children with severe acute malnutrition (SAM) treated with standard nutritional therapy. Methods This was a one-group pretest-posttest quasi-experimental study on children with SAM aged 1 month to 18 years who received standard nutritional therapy for 3 months. We recorded anthropometric data and measured motor and sensory nerve conduction velocity (NCV) of the upper and lower limb nerves before and after the nutritional intervention. Results Thirty participants were included in the study; only 27 underwent post-treatment follow-up nerve conduction testing. All anthropometric indices increased after the intervention, except for body length/height. Moderate correlations were observed between pre-intervention weight and NCVs of the right sural sensory (r=0.496; P=0.005) and left median motor (r=-0.502; P=0.024) nerves. After intervention, conduction velocities of the left median sensory nerve (r=0.750; P=<0.001), right median motor nerves (r=0.521; P=0.015), left ulnar motor nerves (r=0.628; P=0.005), and left tibial motor nerves (r=0.419; P=0.047), had moderate to strong correlations with weight. There were moderate post-treatment correlations between BMI and NCV in the right ulnar (r=0.534; P=0.013) and right fibular (r=0.441; P=0.031) motor NCVs. Conclusion There are significant correlations between weight and some motor and sensory NCVs, as well as between BMI and motor NCVs, after 3 months of receiving nutritional therapy.

Stress levels and menstrual cycles in high school adolescents Saldinar, Alena Briliantyas; Athiah, Medina; Hasanah, Yulisnawati; Nurwanny, Raissa; Aditiawati, Aditiawati
Paediatrica Indonesiana Vol. 65 No. 4 (2025): July 2025
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi65.4.2025.325-30

Background Around 15.5 million (34.9%) adolescents in Indonesia experience stress. Most of the stress in adolescents comes from internal and external academic demands. One of the negative impacts of stress is the disruption of hormonal mechanisms in the female reproductive system, which can affect the menstrual cycle. Objective To analyze the relationship between stress level and menstrual cycle in adolescent girls aged 15 - 17 years who have menses ≥ 2 years. Methods This study used primary data from instruments such as the Depression Anxiety Stress Scale (DASS 42) questionnaire modified by Damanik and the menstrual cycle questionnaire by Aldiba filled on Google forms by 1,565 adolescents from four high schools in Palembang City. We also excluded adolescents with conditions that could potentially bias the study, such as endocrine diseases (pituitary tumors and Cushing's syndrome), athletes with intensive physical activity, use of hormonal drugs, and abnormalities in nutritional status. Results A total of 281 of 961 respondents who met the inclusion criteria were randomly selected through a stratified proportional random sampling method. Of those who reported experiencing stress, 27% experienced moderate stress. The majority of subjects experienced menstrual cycle disorders (55.5%). Adolescents with moderate stress level and above had a greater percentage of menstrual cycle disorders compared to adolescents who did not experience stress (P=0.039). Severe levels of stress were significantly associated with menstrual cycle irregularities (P=0.025) Conclusion Stress levels are significantly associated with menstrual cycle irregularities among high school adolescents in Palembang City.

Title

Found 6 Documents
Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title Search

Found 6 Documents Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title

Found 6 Documents
Search