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All Journal Althea Medical Journal Biomedical Journal of Indonesia
Nursiah Nasution, Nursiah
Department of Anatomy and Cell Biology Faculty of Medicine Universitas Padjadjaran
Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology

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Characteristics and Predisposing Factors of Bacterial Corneal Ulcer in the National Eye Center, Cicendo Eye Hospital, Bandung from January to December 2011 Putri, Astrid Maharani; Heryati, Susi; Nasution, Nursiah
Althea Medical Journal Vol 2, No 3 (2015)
Publisher : Althea Medical Journal

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Background: Corneal ulcer is an emergency condition in ophthalmology, causing visual impairment, mostly by bacterial infection with rapid pathogenesis. The aim of this study was to discover the characteristics of bacterial corneal ulcer patients in the National Eye Center, Cicendo Eye Hospital, Bandung.Methods: A total of 99 medical records consisted of patients diagnosed with bacterial corneal ulcer were selected in this descriptive study. The clinical patterns and predisposing factors of the patients were analyzed. The study also identified the pathogenic bacteria of the cases. This study was carried out in the National Eye Center, Cicendo Eye Hospital, Bandung from January to December 2011 Clinical patterns. The collected data were analyzed and presented in frequency tabulation.Results: The male to female ratio was 2:1, with the average age of 44.4 years. The most common presenting symptom was eye pain (70.7%). Most patients came with decreased visual acuity that was categorized as (near-) blindness (78.8%) and the location of the ulcer was in central area of the cornea (56.5%). The most common predisposing factor was ocular trauma (74.7%) that was caused by exposed to plants. Single-bacterial infection (67.7%) was predominant, with 56 cases (56.6%) of Gram-positive cocci infection.Conclusions:  Bacterial corneal ulcer contributes to 48.8% of all microbial corneal ulcers. Most patients came with mild condition, centralized location, and poor visual function. The common predisposing factor was trauma associated with exposed to plants. DOI: 10.15850/amj.v2n3.505
Profile of Head and Neck Cancer Patients at Department of Otorhinolaringology-Head and Neck Surgery Dr. Hasan Sadikin General Hospital Bandung Rakhmawulan, Inez Aulia; Dewi, Yussy Afriani; Nasution, Nursiah
Althea Medical Journal Vol 2, No 4 (2015)
Publisher : Althea Medical Journal

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Background: Head and neck cancer is a health problem with a high mortality rate. Head and neck cancer are increasing and effect many individuals from diverse backgrounds. Usually patients come with advanced stages, therefore these conditions could lead to decrease their quality of life. Aim of this study was to describe the profile of head and neck cancer patients at the Otorhinolaringology-Head and Neck Surgery Department, Dr. Hasan Sadikin General Hospital Bandung.Methods: A descriptive cross-sectional method was used from medical records of head neck cancer patients at Department of Otorhinolaringology-Head and Neck Surgery, Dr. Hasan Sadikin General Hospital Bandung from 2008 to 2012 that used the total sampling method.Results: There were 665 patients included in this study, which men who participated were 388 and women were 277. Most of them were elementary educated (44.96%), housewives (32.03%), and those aged 46–55 years old (28.33%). There were nasopharyngeal (38.20%), sinonasal (17.29%), larnyx (13.08%), oropharnyx (6.32%), thyroid gland (6.17%), oral cavity (3.91%), hypopharynx (2.41%), and parotid gland (2.26%) cancer. The major histopathological findings were undifferentiated carcinoma (45.41%) and squamous cell carcinoma (22.26%), those were presented with stage I (7.4%), II (13.5%), III (24.4%), and IV (54.7%).Conclusions: Nasopharyngeal carcinoma was the most predominant cases which majority were presented in advanced stage and major histopathology features was undifferentiated carcinoma, while demografic characteristic mostly were in middle aged and older, men with low education background. [AMJ.2015;2(4):474–9] DOI: 10.15850/amj.v2n4.630
Pengaruh Latihan Fisik Intensitas Ringan Dan Sedang Terhadap Perubahan Kadar Hormon Beta–Endorphin Mencit (Mus Musculus L.) Hamil Monica, Ricca; Irfannuddin, Irfannuddin; Nasution, Nursiah
Biomedical Journal of Indonesia: Jurnal Biomedik Fakultas Kedokteran Universitas Sriwijaya Vol 3, No 2 (2017)
Publisher : Fakultas Kedokteran Universitas Sriwijaya

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Wanita hamil sangat dianjurkan untuk tetap melakukan kegiatan sehari-hari secara rutin, termasuk olahraga.  Olahraga atau latihan fisik dapat menghasilkan hormon endorphin. Beta-endorphin merupakan salah satu dari kelompok alami opiat yang salah satu manfaatnya dapat mengurangi rasa nyeri dan mengendalikan perasaan frustasi /stress.  Tujuan dari penelitian ini untuk melihat pengaruh latihan fisik intensitas ringan dan sedang terhadap perubahan kadar hormon beta- endorphin mencit (Mus musculus L.) hamil. Penelitian ini merupakan penelitian eksperimental. Pelaksanaan penelitian dengan pemeriksaan di Laboratorium Terpadu Biologi Molekuler Fakultas Kedokteran Universitas Sriwijaya dengan total 30 sampel. Terdiri dari 2 kelompok perlakuan dan 1 kelompok kontrol. Dari uji ANOVA Nilai Sig. (Signifikasi) kelompok sebesar 0,117 (p value  ? 0,05 ini membuktikan bahwa  tidak ada pengaruh pada latihan fisik intensitas ringan dan juga sedang terhadap perubahan kadar hormon beta–endorphin mencit hamil. Kesimpulan dari uji Post Hoc pada kelompok perlakuan latihan fisik intensitas ringan dan sedang tidak terdapat perbedaan / pengaruh yang bermakna terhadap kadar beta–endorphin 0,630 (p value > 0,05). Disimpulkan bahwa tidak ada pengaruh latihan fisik intensitas ringan dan latihan fisik intensitas sedang terhadap perubahan kadar hormon beta–endorphin pada mencit (Mus musculus L.) hamil.
Co-Authors Astrid Maharani Putri, Astrid Maharani Inez Aulia Rakhmawulan, Inez Aulia Irfannuddin Irfannuddin Monica, Ricca Susi Heryati, Susi Yussy Afriani Dewi