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All Journal Pharmaceutical Sciences and Research (PSR) Makara Journal of Science
Juheini, Juheini
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Pengaruh Kandungan Pati Singkong Terpregelatinasi Terhadap Karakteristik Fisik Tablet Lepas Terkontrol Teofilin Juheini, Juheini; Iskandarsyah, Iskandarsyah; J.A, Animar; Jenny, Jenny
Majalah Ilmu Kefarmasian Vol. 1, No. 1
Publisher : UI Scholars Hub

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In order to make use of pregelatinized Manihot starch in controlled release tablet, the research was done by heating the starch suspension up to its gelatinized temperatur, then dried. The particle size of pregelatinized Manihot starch used were (100-150 mesh) : (150-250 mesh) : smaller than 200 mesh = 3,5 : 1 : 1. The effect of pregelatinized Manihot starch on physical characteristic of Theophyllin controlled relase tablet was known by using 4 formulas containing variety of pregelatinized starch as follows: 30%, 40%, 50%, and 60%. Evaluation on the tablet results including tablet mass and size uniformity, hardness and friability. The result showed that pregelatinized Manihot starch in variable content on these tablet formulas fulfilled the requirement of tablet physical characteristics.
PEMANFAATAN HERBA SELEDRI (Apium graveolens L.) UNTUK MENURUNKAN KOLESTEROL DAN LIPID DALAM DARAH TIKUS PUTIH YANG DIBERI DIIT TINGGI KOLESTEROL DAN LEMAK Juheini, Juheini
Makara Journal of Science Vol. 6, No. 2
Publisher : UI Scholars Hub

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It has been known that celery herbs (Apium graveolens L) contain unsaturated fatty acid, so it could be used as hypocholesterolemia and hypolipidemia agents. A study about the effect of celery herbs juice to cholesterole and lipid blood concentration high feeding cholesterol and lipid diet white rat, has been carried out. In this observation, 30 (thirty) male white rats with 150 to 200 g of weight and 4 months of age were used and divided into five groups randomly. The first group was as a normal control, the second group was given high cholesterol and lipid diet 2,5 g/200 g bow (body weight)/day as a treatment control. For the third, the fourth and the fifth groups, each of them was given with high cholesterol and lipid diet in the same quantity with the second group and get celery herb juice with 0,14 g/200 g bow/day; 0,72 g/200 g bow/day; 3,6 g/200 g bow/day dosage. After six weeks of treatment, the rats were surgeried, the blood was taken out from the heart and then total cholesterol and total lipid concentration were measured. The results showed that all of dosages of celery herb juice has lowering cholesterol and lipid effects, but did not decrease the total cholesterol and total lipid concentration significantly.
Co-Authors . Iskandarsyah J.A, Animar Jenny, Jenny