Emesis gravidarum results in a decrease in appetite, this situation can cause changes in electrolyte balance with potassium, calcium and sodium which result in changes in body metabolism. Therefore, in reducing nausea and vomiting pregnant women should use complementary therapies that can be done easily at home. Pharmacological function is antiemetic (anti-vomiting). Lime has flavonoids, the flavonoid content is known to neutralize acidic digestive fluids, releasing toxins in the body. This study was conducted to determine the differences in the effectiveness of giving a combination of boiled red ginger and mint leaves and a combination of lime and honey on the intensity of nausea and vomiting in first trimester pregnant women. This study used a quasi-experimental research design with a pretest-posttest with control group design. Sampling by purposive sampling. The sample size was 28 pregnant women in the first trimester at the Cikande Public Health Center, Serang Regency. The research instrument is an observation sheet. Data analysis used Mann Whitney statistical test. The results of his research using the Mann Whitney statistical test showed a p-value of 0.498, this means that there is no significant difference in decreasing the intensity of nausea and vomiting in first trimester pregnant women at the Cikande Health Center, Serang Regency between those given boiled red ginger and mint leaves and a combination of lime. and honey for 4 days of treatment. It is hoped that health workers will provide education to pregnant women in traditional medicine or local wisdom.