Article Per Year (5 Year)
p-Index From 2021 - 2026
0.23
P-Index
This Author published in this journals
All Journal Hang Tuah Medical Journal
CHOESNAN EFFENDI
Fakultas Kedokteran Universitas Hang Tuah Surabaya
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Medicine & Pharmacology Nursing Public Health

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
Efek Analgesik Ekstrak Etanolik Daun Mangrove Api-Api Putih (Avicennia alba) terhadap Mencit (Mus musculus L.) Jantan yang Diinduksi Asam Asetat 0,7% ANDREW THEO WILLIAM CHRIS PURMATA; LESTARI DEWI; CHOESNAN EFFENDI
HANG TUAH MEDICAL JOURNAL Vol 18 No 1 (2020): Hang Tuah Medical Journal
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

ABSTRACT Background : Avicennia alba or known as mangrove api-api putih is a type of mangrove species which has many benefits and often to be used by the local Indonesians as traditional medicine. The alcaloid and flavonoid substances derived from Avicennia alba leaves could inhibit pain. This study aims to determine the analgesic effect of Avicennia alba leaves extract in male mice (Mus musculus L.) induced by acetic acid 0,7%. Method :25 mice were divided into 5 groups that were given different therapies. The therapy are 10 mL/kg bw of water, 150 mg/kg bw of acetosal, 250 mg/kg bw; 500mg/kg bw; 1000 mg/kg bw of Avicennia alba leaves extract. 0,7% acetic acid with dose of 10 mL/kg bw is given to each subject intraperitoneally 30 minutes after the therapy to induce pain. The pain is manifested as writhes in mice, the writhes then are counted repeatedly each 10 minutes for 30 minutes. Result:: mean of writhes in group treated with Avicennia alba leaves extract in 250 mg/kg bw and 500 mg/kg bw with each value 6,20 and 9,40 are less than mean of writhes in negative control group with value 31,40. %inhibition of Avicennia alba leaves extract with dose of 250 mg/kg bw and 500 mg/kg bw respectively are 80,25% and 70,06%. Conclusion : Avicennia alba leaves extract in 250 mg/kg bw and 500 mg/kg bw dosage showed analgesic effect in male mice (Mus musculus L.) induced with 0,7% acetic acid.
Pengaruh Pemberian Ekstrak Biji Jintan Hitam terhadap Kadar Kolesterol HDL dan LDL Rattus Norvegicus Jantan Galur Wistar yang Diberi Diet Tinggi Lemak RETNO SETYA KEMALA; CHOESNAN EFFENDI; ASAMI RIETTA KUMALA
HANG TUAH MEDICAL JOURNAL Vol 18 No 2 (2021): Hang Tuah Medical Journal
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

ABTRACT Background: There are a lot of various kinds of plants such as Black Cumin (Nigella sativa L.) which is believed by the people to increase HDL and decrease LDL levels in the blood. The purpose of this experiment to know the effect of extract black cumin seeds (Nigella sativa L.)can increase HDL and decrease LDL cholesterol levels of white rats (Rattus norvegicus). Method: This experiment using 24 of rats which divided into 4 groups, namely the negative control group, positive control group, the treatment group one dosage 126 mg/KgBWand the treatment group two dosage 252 mg/KgBW. This research was carried out for 28 days and continued by termination. Result :In the One way ANOVA test, HDL levels obtained significant values of 0.134 and LDL levels of 0.070 which means p> 0.05 and showed that black cumin seed extract (Nigella sativa L.) there’s no different. Conclusion: black cumin seed extract (Nigella sativa L.) had no effect for increasing HDL and decreasing LDL cholesterol levels of white rats (Rattus norvegicus)
Co-Authors ANDREW THEO WILLIAM CHRIS PURMATA Lestari Dewi RETNO SETYA KEMALA