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Comparison of Effectiveness of Hydropobic Cutimed Sorbact Versus Cadexomer Iodine 0.9% on Healing of Diabetic Foot Ulcer: A Randomized Control Trial Septian Mixrova Sebayang; Asmat Burhan
Journal of Wound Research and Technology Vol. 1 No. 1 (2024): November - May 2024
Publisher : Indonesian Science Media

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70196/jwrt.v1i1.5

Abstract

Background: Diabetic foot ulcers have risen with DM. The IDF reports 15-25% of diabetics get foot ulcers, rising to 25% over time. Due to biofilm and bacteria growth, diabetic ulcers need advanced wound therapy using antimicrobial dressings. Modern antibacterial treatments include sorbact hydrophobic and 0.9% cadexomer iodine. Purpose: Analyse the effectiveness of cutimed sorbact hydrophobic with cadexomer iodine 0.9% on diabetic ulcer infection. Methods: A single-blind, fold-over, randomised controlled study. Patients with diabetes who developed foot ulcers between September 1 and December 1, 2023. One hundred sixty-two participants were randomly assigned to receive cutimed sorbact hydrophobic or cadexomer iodine 0.9%.  After 120 days, both groups. Results: It was found that the two groups had similar body mass index (0.364), wound size (0.317), and baseline age (p=0.432). The mean difference in confidence value of -0.16 (OR -2.54 to 1.29; p=0.058) showed that diabetic foot ulcers in both groups had similar wound size on the thirtyth day. On day 60 of treatment, Sorbact Hydropobic showed a difference of 22.56±9.87 compared to Cadexomer Iodine 0.9%, with an MD-CI value of -6.75 (OR 5.19 to -0.34; p=0.039 At 90 days of treatment, cadexomer iodine showed a significant difference from sorbact hydropobic (9.73±2.14), with an MD-CI value of -12.29 (OR -9.19 to -4.26; p=0.016; R2=-0.417). Conclusion: Sorbact Hydropobic reduces wound size, infection, and bacterial resistance, speeding chronic wound healing. On chronic wounds, hydropobic sorbact can be used as a primary dressing.
Analysis of Risk Factors for the Occurrence of Diabetic Foot Ulcers in Patients with Type II Diabetes Mellitus Kaylan Wesle Elian; André Athrison; Stephany Daleska Cielo; FIrolella Camia Angelo; Barbara Cathrine Nichole; Asmat Burhan; Indah Susanti
Journal of Wound Research and Technology Vol. 1 No. 2 (2024): June - October 2024
Publisher : Indonesian Science Media

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70196/jwrt.v1i2.24

Abstract

Background: Diabetes Mellitus (DM) has become a prevalent disease, imposing a significant burden on public health due to its widespread occurrence and association with numerous disabilities and fatalities. Uncontrolled DM can lead to severe metabolic complications and long-term vascular issues, including microangiopathy and macroangiopathy. Additionally, individuals with DM are highly susceptible to foot infections, which can escalate into gangrene if not properly managed. Purpose: This study aimed to determine the risk factors for diabetic foot ulcers in patients with Type II Diabetes Mellitus at the Hospital Infatil e Maternidade Jardim Amalia Methods: The research employed an analytical survey method with a case-control study design. Purposive sampling was utilized to select a total of 134 participants, comprising 67 individuals in the case group (those with diabetic foot ulcers) and 67 in the control group (those without diabetic foot ulcers). Data collection was conducted using a structured questionnaire, and the results were analyzed using the Odds Ratio (OR) test to identify significant risk factors. Findings: The findings of the study indicated that age is a risk factor for developing diabetic foot ulcers in patients with Type II DM, with an OR of 3.15 (95% CI: 0.43-17.216). The duration of diabetes also emerged as a significant risk factor, with an OR of 3.13 (95% CI: 0.62-14.12). Furthermore, foot care practices were identified as a crucial risk factor, with an OR of 4.13 (95% CI: 0.72-12.45). Conclusion: this study demonstrates that age, the length of time a patient has had diabetes, and their foot care routines are significant risk factors for the development of diabetic foot ulcers in patients with Type II Diabetes Mellitus at Hospital Infatil e Maternidade Jardim Amalia. These findings underscore the importance of early intervention and targeted patient education to mitigate these risks and improve patient outcome
Efficacy of Bioactive Dressings Compared to Passive Dressings in Promoting Wound Healing in Diabetic Foot Ulcers: A Randomized Controlled Trial Supansa Srisawat; Nattay Kittipong; Rungnapa Pimchanok; Nur Aisyah binti Hassan; Ain Syuhada binti Salleh; Indah Susanti; Asmat Burhan
Journal of Wound Research and Technology Vol. 2 No. 1 (2025): November - May 2025
Publisher : Indonesian Science Media

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70196/jwrt.v2i1.43

Abstract

Background: Diabetic foot ulcers (DFU) are a major complication of diabetes, leading to significant morbidity, increased healthcare costs, and a higher risk of amputations. Traditional wound care methods, such as passive dressings, have limitations in promoting faster healing and infection control. Bioactive dressings, which include antimicrobial and regenerative components, have shown promise in improving wound healing outcomes in DFU patients, but robust evidence comparing their efficacy to passive dressings in clinical practice remains scarce. Purpose: To evaluate the efficacy of bioactive dressings compared to passive dressings in promoting wound healing in patients with diabetic foot ulcers. Method: A randomized controlled trial was conducted in a single center, enrolling 90 adults with chronic DFUs. Participants were randomly assigned to receive either bioactive dressings (n=45) or passive dressings (n=45) for a 3-month treatment period. Inclusion criteria included adults aged 18–75 years with DFUs of at least 6 weeks duration and Wagner grade 2 or higher ulcers. The primary outcome was wound size reduction, assessed at baseline, 1 month, 2 months, and 3 months. Secondary outcomes included wound depth, infection control, epithelialization, and granulation. Results: At 1 month, the bioactive dressing group showed a significantly greater reduction in wound size compared to the passive dressing group (mean reduction 45% vs. 30%, p=0.003). Bioactive dressings also demonstrated superior infection control (p<0.001) and promoted faster epithelialization (p=0.022) and granulation (p=0.015). The control group exhibited slower healing rates and less pronounced improvements in secondary outcomes. Conclusions: Bioactive dressings significantly improve wound healing, infection control, and tissue regeneration in patients with diabetic foot ulcers compared to passive dressings. These findings support the integration of bioactive dressings as an effective treatment option in DFU management, particularly in the early stages of wound healing. Further studies with longer follow-up are needed to assess long-term outcomes