Cikra Ikhda Nur Hamida Safitri
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AKTIVITAS ANTIDIABETES KOMBINASI EKSTRAK LABU KUNING DAN BROTOWALI SECARA IN VIVO Cikra Ikhda Nur Hamida Safitri; Misbahatul Khoiriyah
Jurnal Medical Laboratory Vol. 3 No. 1 (2024): Januari: Jurnal MedLab
Publisher : Sekolah Tinggi Ilmu Kesehatan Kesetiakawanan Sosial Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/medlab.v3i1.223

Abstract

Cucurbita Moschata are rich in polyphenolic antioxidants such as flavonoids which can be used to lower blood sugar levels. Cucurbita Moschata can be formulated into biscuits. The aim is to determine the activity of cucurbita moschata and tinospora crispa extracts on reducing blood sugar in mice (Mus muculus). The research aims to create a Cucurbita Moschata biscuit formula that contains high levels of resistant starch and beta carotene but has the lowest impact on increasing blood sugar levels. This research method is experimental by making an antidiabetic formulation in mice. Mice were divided into normal groups, K groups (CMC NA 1%), groups with varying doses of 100 mg/kg, 300 mg/kg and 600 mg/kg, and positive groups (glibenclamide 0.65 mg/kg). Using the two way anova analysis method. The results showed the effect of reducing blood sugar levels in mice at doses of 100mg/kg (17.3%), 300mg/kg (29.3%), 600 mg/kg (35.2%) and the positive group (44.3%). The 600mg/kg group (35.2%) provided the highest reduction in blood sugar levels, which was close to positive (44.3%) compared to doses of 100mg/kg (17.3%), 300 mg/kg (29.3%). The conclusion of this study is that anti-diabetes biscuits, a combination cucurbita moschata and tinospora crispa , have antihyperglycemic activity in vivo.
Formulasi Dan Uji Mutu Fisik Masker Gel Peel Off Kombinasi Sisik Ikan Bandeng Dan Kulit Jeruk Nipis Cikra Ikhda Nur Hamida Safitri; Elly Purwati; Khoirunnisa Fibrianti
An-Najat Vol. 2 No. 2 (2024): MEI : An-Najat: Jurnal Ilmu Farmasi dan Kesehatan
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/an-najat.v2i2.1088

Abstract

Lime contains flavonoids which have antioxidant properties by inhibiting free radicals. Meanwhile, milkfish scales contain 0,3% collagen which can be used as anti-aging for skin. Bot function as skon care products with an alternative formulation into a peel off gel mask. The aim of this research is to determine whether a combination of milkfish scale powder and lime peel can be formulated into a peel off gel mask. The method used is an experimental method by immersion extraction in 70% ethanol solvent. The formulation of milkfish scales is 1%, 3%, and 5%. Lime extract uses 0,6%; 1,2%; and 1,8%. Evaluation of physical quality in accordance with SNI masks 16-6070-1999. The results showed that the three formulations were not homogeneous due to the presence of insoluble fish scale powder, there was no changes in the organoleptic test parameters, the pH test range (4 -6), the test range spreadability of (3,7 – 7,5 cm), dry time (15 minutes), and viscosity test (1189 mPa.S-3598 mPa.S). The conclusion of this research is that lime peel and milkfish scales can be formulated as active ingredients for peel off gel masks and the physical quality test of peel off gel mask preparations meet the requirements.
Aktivitas Sedatif Nutrasetikal Jelly Drink Kombinasi Ekstrak Putri Malu (Mimosa Pudica Linn.) dan Ekstrak Secang (Caesalpinia Sappan L.) Sebagai Pencegah Mental Illness Cikra Ikhda Nur Hamida Safitri; Vania Angel
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 2 (2024): March : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v2i2.326

Abstract

Insomnia is a sleep disorder that often occurs in teenagers. Insomnia can be treated using sedative hypnotic drugs but this can cause dangerous effects. Therefore, alternative natural ingredients are needed, such as Putri Malu and Secang, which are formulated in the form of jelly drinks as nutrasetikals. This research used 20 female mice as test animals which were divided randomly into 5 grups. The method used was the Traction Test and the data collected was the length of time the mice turned and the time the mice fell. In the positive control grup, Diazepam, distilled water and agar, the average time for mice to fall was 62.5 seconds and the time to turn around was 62.9 seconds. In the negative control grup, Jelly Drink combination of Putri Malu and Secang 0.68 g/kgBW, showed that the time for mice to fall was 106.6 seconds and the time to turn around was 128.5 seconds. In conclusion, the Jelly drink combination of Putri Malu and Secang has a sedative effect and has the potential to prevent insomnia as seen by the need for mice in the Jelly drink grup who had less time to fall and turn around.