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All Journal ELS Journal On Interdisciplinary Studies in Humanities MEDULA Jurnal Ilmiah Fakultas Kedokteran Universitas Halu Oleo
Jumraini Tammasse
Hasanuddin University
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Public Health Social Sciences Other

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Transcranial Magnetic Stimulation Can Improve Cognitive Function and Brain-Derived Neurotrophic Peptide Levels in Post-Ischemic Stroke Patients Ulima Rahma Asri; Jumraini Tammasse; Andi Kurnia Bintang; Rina Masadah; Muhammad Akbar; David Gunawan Umbas
MEDULA: Jurnal Ilmiah Fakultas Kedokteran Universitas Halu Oleo Vol. 12 No. 1 (2024): Desember
Publisher : MEDULA: Jurnal Ilmiah Fakultas Kedokteran Universitas Halu Oleo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46496/medula.v12i1.41

Abstract

ABSTRACT Background: Stroke can cause a significant burden of morbidity, including complications of impaired cognitive function. The problem being investigated is hypothesized to be related to brain-derived neurotrophic factor (BDNF), which can be increased by repetitive transcranial magnetic stimulation (rTMS). Purpose(s): To evaluate the effect of Repetitive Transcranial Magnetic Stimulation (rTMS) on serum BDNF levels and cognitive function in ischemic stroke patients. Methods: A pre-test post-test control group, experimental study design, was applied to research conducted at Dr Wahidin Sudirohusodo Makassar and network hospitals in June 2023 until the sample size was met. All ischemic stroke patients who experienced impaired memory function were divided into control (medicamentous, n=10) and treatment (medicamentous + rTMS, n=11). Both at baseline and 14 days following therapy, their BDNF levels and MoCA-INA scores were assessed. ELISA examination is used to measure BDNF levels. The dependent T-test was used to analyze changes in MoCA-INA and BDNF scores in each group. Results: In the treatment group, the median MoCA INA score (26.00 (18.00-28.00) vs. 16.00 (13.00-21.00; p=0.001)) and BDNF levels (1.66 (0.78-3.59) vs. 1.55 (0.01-2.76); p=0.002) increased in two weeks. In contrast, the MoCA-INA score and BDNF levels in the control group did not show a statistically significant difference over a two-week period. MoCA-INA scores and BDNF levels in the treatment group showed a significant and favorable correlation, but not in the control group. Conclusion: rTMS can improve patients' cognitive function after ischemic stroke by improving BDNF levels. Keywords: Brain-derived neurotrophic factor, cognitive function, ischaemic stroke, repetitive transcranial magnetic stimulation
The Effectiveness of Using Kinect-Based Dyslexia Therapy in Improving Reading Ability in Dyslexic Children: A Linguistic Study Tammasse Tammasse; Jumraini Tammasse; Iin Fadhilah Utami; Fakhriawan Fathu Rahman
ELS Journal on Interdisciplinary Studies in Humanities Vol. 5 No. 3 (2022): September
Publisher : Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (387.715 KB) | DOI: 10.34050/elsjish.v5i3.23168

Abstract

Dyslexia is a learning disorder characterized by difficult in reading, writing, or spelling. People especially children with dyslexia have difficult to identify spoken words and converting them into letters or sentences. The aims of this study are 1) to find out the early symptoms of dyslexia in children, 2) to reveal the effectiveness of using video game media (kinect-based dyslexia therapy media) in improving reading skills in dyslexic children. This research used quantitative method. This research is an experimental longitudinal because there is an intensive observation of the subject within a certain period of time. The result of this study is to reduce the dyslexia children as much as possible to read by using the intervention “Kinect-Based Dyslexia Therapy” (LexiPal). Strong evidence of the success of the LexiPal intervention can be seen through the experimental method (calculated the difference in the position of the treatment group and the control group at the end of the experiment). Calculations are carried out through simple statistical calculations.
Co-Authors Andi Kurnia Bintang David Gunawan Umbas Fakhriawan Fathu Rahman Iin Fadhilah Utami Muhammad Akbar Rina Masadah Tammasse Tammasse Ulima Rahma Asri