Article Per Year (5 Year)
p-Index From 2020 - 2025
0
P-Index
This Author published in this journals
All Journal International Journal of Agriculture System
Hanapi Usman
Chemistry Department of Mathematic and Natural Science Faculty, Hasanuddin University, South Sulawesi, 90245
Agriculture, Biological Sciences & Forestry

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

 1 
Structural Elucidation of Secondary Metabolites in Sponge (Callyspongia pseudoreticulata) with N-Hexane Extract M. Nurdin; Hanapi Usman; Ambo Ala; Baharuddin Baharuddin
International Journal of Agriculture System VOLUME 2 ISSUE 1, JUNE 2014
Publisher : Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (616.293 KB) | DOI: 10.20956/ijas.v1i1.23

Abstract

Sponge is one of the marine species that has a high bioactivity and contains secondary metabobolite compound which can be used as antibiotic and medicine. Terpenoid compound derivatives have been successfully isolated from sponge Callyspongia pseudoretilulata by a method in which the n-hexane extract weighing 11.28 g was fractionated using vacuum column chromatography with a non-polar eluent, n-hexane. The polarity of this eluent was improved by ethyl acetic resulting in fairly polar eluent, methanol. A total of 27 fractions were obtained and one of the compounds from n-hexane extract was structurally elucidated by NMR spectroscopy and two dimensions of homonuclear and heteronuclear (1H, 13C, DEPT, H-H COSY, HMQC, and HMBC). The identified compound was a hydrocarbon (1-ethyl cyclo hex cosana-1-amin) that indicated LC50 of 60.58 against A. salina and has a great potential as antitumor or anticancer.
Co-Authors Ambo Ala Baharuddin Baharuddin M. Nurdin