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Ylang Flower Gel Antifungal Effectiveness Ariyanti Ariyanti; Eni Masruriati; Dwi Setyowati; Filza Mazaya Nurulita
Indonesian Journal of Global Health Research Vol 4 No 2 (2022): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Ylang flower (Cananga odorata) has effectiveness as an antibacterial and antifungal because the ylang flower plant contains the main compounds, namely -linalool (12.8%), -caryophyllene (8.99%), farsenol (6.8%), germacren- D (5.35%), -bergamotene (8.45%), and benzyl benzoate (5.9%). The substances contained in ylang flower essential oil are alcohol (53% - 65%) with methylbenzoate esters, linalool esters, and terpineol esters, sesquiterpenes which have anti-inflammatory, antimicrobial, antioxidant properties, and also prevent bacteria and germs and have anti-inflammatory activity. local anesthetic. The essential oil of ylang flower has antibacterial properties because the substances contained therein are in the form of an active component called kariofilen. This karyophylene compound has anti-inflammatory, antimicrobial and germ-preventing properties. This study was conducted to determine the effectiveness of the antifungal contained in the gel from ylang flower (Cananga odorata) using the disc diffusion method, which is the method used in microbial testing, and to determine the concentration of hydroxy propyl methyl cellulose (HPMC) with the addition of propylene glycol used. as a humectant in order to maintain the stability of the gel preparation on physical properties and the effectiveness of ylang flower essential oil as an antifungal by making a gel preparation. The essential oil gel from ylang flower was used as a test of the physical properties of the gel (pH, viscosity, homogeneity, dispersion and adhesion). The results of the research that have been carried out prove that the gel formula from ylang flower extraction using HPMC base with a concentration of 5% has good physical properties of the gel because it is seen in the organoleptic test, pH test, viscosity, homogeneity, dispersion and adhesion meet the specified requirements. in stock. It can be concluded in this study that the gel preparation of ylang flower has antifungal activity or can inhibit the presence of M.furfur fungus from a gel based on HPMC with a concentration of 5% has good gel physical properties and better antifungal activity compared to gel which has a better concentration 10% and 15%.

Dissolution Effectiveness of Moringa Leaf Pills (Moringa Oleifera L.) and Aloe Vera (Aloe Barbadensis Miller) Ariyanti Ariyanti; Eni Masruriati; Dwi Setyowati; Filza Mazaya Nurulita
Proceedings of the International Conference on Nursing and Health Sciences Vol 3 No 2 (2022): July-December 2022
Publisher : Global Health Science Group

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/picnhs.v3i2.1377

Oral preparations with level solubility tall so speed dissolution substance active from form preparations Becomes more fast, anyway with preparations with speed dissolution low so speed dissolution substance active from form preparations Becomes slow, so rate absorption drug more slow as well as produce bioavailability low. Materials potion drug traditional for example from ingredient plant natural around which not yet experience processing whatever. Ingredient nature used _ as drug traditional in study this is plant leaf moringa and tongue crocodile. Leaf Moringa (Moringa oleifera L.) has various type effect therapy like antimicrobial, anticancer, anti-inflammatory, effect antidiabetic as well as as antioxidants. Compound chemical in the leaves _ moringa that is there is polyphenols, acids phenolics, flavonoids, glucosinolates, alkaloids, vitamins, acids phenolics, isothiocyanates, tannins and saponins. Plant tongue crocodile (Aloe barbadensis Miller). kindly chemistry, tongue crocodile consists over 90% water and 4% carbohydrates, the rest consists of minerals, 17 kinds amino acids. Gel found on the tongue crocodile there is content substance antibacterial as well as possible antifungal _ stimulate tiroblast . Study this aim for knowing effectiveness dissolution pill from leaf moringa and tongue crocodile with use method study experimental. Result of study this yield extract leaf moringa and tongue crocodile obtained on the leaves moringa by 6.38% and tongue crocodile 6.268%. Assessment test preparations pill Fulfill condition uniformity weight and fulfill dissolution test conditions because time the required crush for 30 minutes.

The Effectiveness of Tomato Fruit Antioxidant Handbody Lotion Ariyanti Ariyanti; Eni Masruriati; Dwi Setyowati; Filza Mazaya Nurulita
Indonesian Journal of Global Health Research Vol 4 No 3 (2022): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Antioxidants are found in various types of fruits and vegetables, one of which is tomatoes ( Licopersicon esculentum Mill ). Tomatoes contain lycopene, flavonoids and vitamin C compounds as antioxidants. Tomato fruit is made into juice by using the extraction method. Tomatoes with direct use are less effective, so they are made in the form of pharmaceutical preparations in the form of hand body lotion gel using tomato juice. The purpose of this study was to determine the effectiveness of tomatoes as antioxidants in handbody lotion gel preparations using the DPPH method. This research used experimental research method with 3 concentration formulas of tomato juice handbody lotion, namely 5%, 10% and 15%. The physical evaluation test showed that the results had met the physical requirements of the handbody lotion (organoleptic, homogeneity, spreadability, adhesion, viscosity, pH, lotion type and hedonic test). The results showed that tomatoes have effectiveness as antioxidants. This test was carried out using the DPPH method on the preparation of handbody lotion gel tomato juice formula II, the IC50 was 6,620 g/mL, which was greater than formulas I and III. The smallest IC50 value was obtained from formula III, which was 5,205 g/mL. The smaller the IC50 value, the stronger the antioxidant power.

Ylang Flower Gel Antifungal Effectiveness Ariyanti Ariyanti; Eni Masruriati; Dwi Setyowati; Filza Mazaya Nurulita
Indonesian Journal of Global Health Research Vol 4 No 2 (2022): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Ylang flower (Cananga odorata) has effectiveness as an antibacterial and antifungal because the ylang flower plant contains the main compounds, namely -linalool (12.8%), -caryophyllene (8.99%), farsenol (6.8%), germacren- D (5.35%), -bergamotene (8.45%), and benzyl benzoate (5.9%). The substances contained in ylang flower essential oil are alcohol (53% - 65%) with methylbenzoate esters, linalool esters, and terpineol esters, sesquiterpenes which have anti-inflammatory, antimicrobial, antioxidant properties, and also prevent bacteria and germs and have anti-inflammatory activity. local anesthetic. The essential oil of ylang flower has antibacterial properties because the substances contained therein are in the form of an active component called kariofilen. This karyophylene compound has anti-inflammatory, antimicrobial and germ-preventing properties. This study was conducted to determine the effectiveness of the antifungal contained in the gel from ylang flower (Cananga odorata) using the disc diffusion method, which is the method used in microbial testing, and to determine the concentration of hydroxy propyl methyl cellulose (HPMC) with the addition of propylene glycol used. as a humectant in order to maintain the stability of the gel preparation on physical properties and the effectiveness of ylang flower essential oil as an antifungal by making a gel preparation. The essential oil gel from ylang flower was used as a test of the physical properties of the gel (pH, viscosity, homogeneity, dispersion and adhesion). The results of the research that have been carried out prove that the gel formula from ylang flower extraction using HPMC base with a concentration of 5% has good physical properties of the gel because it is seen in the organoleptic test, pH test, viscosity, homogeneity, dispersion and adhesion meet the specified requirements. in stock. It can be concluded in this study that the gel preparation of ylang flower has antifungal activity or can inhibit the presence of M.furfur fungus from a gel based on HPMC with a concentration of 5% has good gel physical properties and better antifungal activity compared to gel which has a better concentration 10% and 15%.

Effect of Using Moringa Leave (Moringa Oleifera L.) and Pineapple (Ananas Comosus) Leaf Lotion Gel Lotion on Skin Moisture Ariyanti Ariyanti; Eni Masruriati; Dwi Setyowati; Filza Mazaya Nurulita
Proceedings of the International Conference on Nursing and Health Sciences Vol 4 No 1 (2023): January-June 2023
Publisher : Global Health Science Group

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/picnhs.v4i1.1717

The compounds contained in Moringa leaves are rich in phenolic acids, flavonoids, alkaloids, tannins, glucosinolates and isothiocyanates, all of which are antioxidants. Moringa leaves contain B2 which is useful for treating and maintaining skin moisture. Pineapple fruit contains vitamin C and vitamin A, the second vitamin is known to have antioxidant activity that can stop the reaction of forming free radicals. Moringa leaves and pineapple contain antioxidant compounds which are useful as skin moisturizers which are formulated in the form of a gel lotion. This study aims to determine the effect of using moringa leaf extract gel lotion and pineapple fruit on skin moisture. This study was initiated by formulating lotion preparations with the addition of concentrations of moringa leaf extract and pineapple fruit, namely concentrations of 3% (F1) 4% (F2) 5% (F3). Lotion gel was evaluated for physical stability by testing pH, viscosity, adhesion, spreadability, irritation test, specific gravity test and skin moisture test. This study uses an experimental method. The results showed that the formula concentrations of 3%, 4% and 5% all met the requirements of the physical stability test as a skin moisturizing lotion gel preparation. The higher the concentration of the extract, the wider the spreadability and viscosity value obtained, has no effect on adhesion and pH value. Lotion preparations of moringa leaf and pineapple fruit extracts with a concentration of 5% have a high ability as skin moisturizers. The results showed that the formula concentrations of 3%, 4% and 5% all met the requirements of the physical stability test as a skin moisturizing lotion gel preparation. The higher the concentration of the extract, the wider the spreadability and viscosity value obtained, has no effect on adhesion and pH value. Lotion preparations of moringa leaf and pineapple fruit extracts with a concentration of 5% have a high ability as skin moisturizers. The results showed that the formula concentrations of 3%, 4% and 5% all met the requirements of the physical stability test as a skin moisturizing lotion gel preparation. The higher the concentration of the extract, the wider the spreadability and viscosity value obtained, has no effect on adhesion and pH value. Lotion preparations of moringa leaf and pineapple fruit extracts with a concentration of 5% have a high ability as skin moisturizers.

Analysis of Moringa Leaf Nanoemulgel (Moringa Oleifera L.) and Aloe Vera as A Moisturizer for Male Rabbits in New Zealand Ariyanti Ariyanti; Eni Masruriati; Dwi Setyowati; Filza Mazaya Nurulita
Indonesian Journal of Global Health Research Vol 5 No 3 (2023): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v5i3.2057

Moisturizing lotion is an emollient group that contains more water which is useful for increasing skin hydration. One of the active ingredients in the moisturizing lotion is the antioxidant compounds found in Moringa oleifera L. and aloe vera leaves. Moringa leaves contain flavonoids such as quercetin, which have strong antioxidant activity that can neutralize free radicals. Aloe vera contains vitamins A, B, C, E, calcium, amino acids, enzymes and polysaccharides which are useful as moisturizing agents. The formulation of Moringa leaf extract and aloe vera was made in the form of nanoemulgel lotion as a skin moisturizer, before being formulated into a lotion preparation, a phytochemical screening was carried out to determine the content of the extract compounds. This study aims to determine the effect of using nanoemulgel lotion of moringa leaf extract and aloe vera on skin moisture. The formulation of nanoemulgel lotion of moringa leaf extract and aloe vera uses different concentrations of active substances of 3% (F1), 6% (F2) and 9% (F3). The physical evaluation carried out included organoleptic tests, homogeneity, pH, spreadability, viscosity and skin moisture. The results showed that all formulations with concentrations of 3%, 6% and 9% met the requirements for the evaluation test for nanoemulgel lotion for skin moisturizing. The higher the concentration of the active substance, the greater the spreadability and viscosity value obtained, no effect on pH. Nanoemulgel lotion preparations of moreinga leaf extract and aloe vera with a concentration of 9% (F3) have high ability as skin moisturizers.

Sosialisasi Penggunaan Pemutih dalam Kosmetik dan Pembuatan Sabun Minyak Jelantah (MIJEL) Di Kelurahan Bumiayu Weleri Ariyanti Ariyanti; Eni Masruriati; Ika Pratiwi; Dwi Setyowati; Filza Mazaya Nurulita
Prosiding Seminar Nasional Pengabdian Kepada Masyarakat: Peduli Masyarakat Vol 2 No 2 (2022): Prosiding Seminar Nasional Pengabdian Kepada Masyarakat: Peduli Masyarakat: Oktob
Publisher : Sekolah Tinggi Ilmu Kesehatan Kendal Bekerjasama dengan CV Global Health Science Group

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/psnpkm.v2i2.1282

Kebutuhan minyak goreng di rumah tangga pada kelurahan Bumiayu Weleri menjadi cukup banyak. Minyak jelantah atau minyak bekas penggorengan setelah tidak digunakan lagi maka dibuang di tanah, selokan atau pada air mengalir yang berakibat merusak dan mencemari lingkungan. Minyak jelantah bisa dimanfaatkan lagi sesudah proses penjernihan serta dibuat sebagai olahan produk non pangan yang tentunya bermanfaat bagi kebersihan masyarakat dan keperluan dalam rumah tangga salah satunya dijadikan bahan baku sebagai pembuatan sabun cuci piring. Kegiatan pengabdian masyarakat ini melibatkan masyarakat khususnya kaum ibu rumah tangga dan para remaja di kelurahan Bumiayu Weleri. Tujuan pengabdian masyarakat ini adalah sosialisasi dahulu mengenai edukasi penggunaan pemutih dalam kosmetik yang berbahaya jika digunakan dalam jangka panjang dan dilanjut sosialisasi mengenai manfaat limbah minyak jelantah untuk menjadikan alternatif solusi dalam mengatasi banyaknya limbah dari minyak hasil penggorengan yang sudah tidak digunakan agar tidak mencemari lingkungan dan praktik pembuatan sabun cuci piring dari limbah minyak jelantah. Pengabdian masyarakat ini menggunakan metode Community Development dengan beberapa langkah yaitu pengumpulan data, perumusan masalah, perencanaan program, aksi dan komunikasi, serta evaluasi. Hasil dari kegiatan sosialisasi pengabdian masyarakat dan praktik pembuatan sabun cuci piring dari limbah minyak jelantah berjalan dengan lancar dan sesuai rencana kegiatan. Masyarakat yang mengikuti kegiatan sangat antusias karena banyak yang aktif bertanya.

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