Nuniek Nizmah Fajriyah
Universitas Muhammadiyah Pekajangan Pekalongan, Indonesia

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Test of ?-Amylase Inhibition Activity in Ethanol Extract of Fennel Leaves (Foeniculum vulgare Mill.) Using Elisa Reader Dwi Bagus Pambudi; Nuniek Nizmah Fajriyah; Retno Aulia Maharisti
Urecol Journal. Part C: Health Sciences Vol. 1 No. 1 (2021): January - June
Publisher : Konsorsium LPPM Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (191.263 KB) | DOI: 10.53017/ujhs.1

Abstract

Fennel has been cultivated in Indonesia as a spice and medicinal plant. Fennel can produce fennel oil, which is the result of distillation from dry and ripe fennel fruit powder, while fennel leaves are mainly cooked to make vegetables. The ?-amylase enzyme plays an important role in the breakdown of oligosaccharides and disaccharides into monosaccharides so that they are ready for absorption. Inhibition of the ?-amylase enzyme can delay and prolong the digestion time of carbohydrates, causing a decrease in the rate of glucose absorption and preventing an increase in postpandrial plasma glucose levels. Therefore, this study aims to investigate the ethanol extract of fennel leaves (Foeniculum vulgare Mill.) Against the inhibitory activity of the ?-amylase enzyme using Elisa Reader. The experimental research method was applied to test the ethanol extract of secondary metabolite compounds from fennel leaves against the inhibition of ?-amylase enzyme activity. The results showed that the IC50 value in the fennel leaf extract was 1.432 ?g/mL while the IC50 acarbose as a comparison was 3.340 ?g/mL. In conclusion, the ethanol extract of fennel leaves can be used to reduce blood sugar levels.
Management Of Immune Formation for Covid-19 Prevention Through Vaccination Irnawati; Benny Arief Sulistyanto; Nuniek Nizmah Fajriyah
Urecol Journal. Part C: Health Sciences Vol. 1 No. 2 (2021): August-Dec
Publisher : Konsorsium LPPM Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (321.363 KB) | DOI: 10.53017/ujhs.78

Abstract

The Covid-19 disease is still very high in transmission. The total number of confirmed Covid-19 patients on October 9, 2021 is 5615 people (Pekalongan City), 7927 people (Pekalongan Regency) and 320 people (Pekalongan City), 562 people (Pekalongan Regency) died from Covid-19. The existence of a vaccine is clearly the best hope to reduce the transmission rate of the Covid-19 virus which is getting out of control. Vaccines and health education about the benefits of the Covid-19 vaccine and Post-Immunization Adverse Events (AEFI) aims to: (1) increase knowledge about the benefits of the Covid vaccine -19 to prevent the transmission of Covid-19; (2) increase public awareness to carry out the Covid-19 vaccine and not panic if AEFIs appear. The target of this community service is consisting of students and alumni of Pekajangan Muhammadiyah University, people from Pekalongan Regency, Pekalongan City, Batang Regency, Pemalang Regency and several other communities in Central Java area. The activities include registration and verification of data, screening history and simple physical examinations, as well as conducting education on Covid-19 vaccination, implementation of vaccines, submission of vaccine certificates and health education regarding AEFI. The results of this community service activity are that 1600 people have been vaccinated, know about the benefits of vaccines and AEFI. It is hoped that people who have been vaccinated will continue to apply the 5M health protocol (wearing masks, washing hands with soap, maintaining distance, limiting mobility and staying away from crowds).
Test of ?-Amylase Inhibition Activity in Ethanol Extract of Fennel Leaves (Foeniculum vulgare Mill.) Using Elisa Reader Dwi Bagus Pambudi; Nuniek Nizmah Fajriyah; Retno Aulia Maharisti
Urecol Journal. Part C: Health Sciences Vol. 1 No. 1 (2021): January - June
Publisher : Konsorsium LPPM Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53017/ujhs.1

Abstract

Fennel has been cultivated in Indonesia as a spice and medicinal plant. Fennel can produce fennel oil, which is the result of distillation from dry and ripe fennel fruit powder, while fennel leaves are mainly cooked to make vegetables. The ?-amylase enzyme plays an important role in the breakdown of oligosaccharides and disaccharides into monosaccharides so that they are ready for absorption. Inhibition of the ?-amylase enzyme can delay and prolong the digestion time of carbohydrates, causing a decrease in the rate of glucose absorption and preventing an increase in postpandrial plasma glucose levels. Therefore, this study aims to investigate the ethanol extract of fennel leaves (Foeniculum vulgare Mill.) Against the inhibitory activity of the ?-amylase enzyme using Elisa Reader. The experimental research method was applied to test the ethanol extract of secondary metabolite compounds from fennel leaves against the inhibition of ?-amylase enzyme activity. The results showed that the IC50 value in the fennel leaf extract was 1.432 ?g/mL while the IC50 acarbose as a comparison was 3.340 ?g/mL. In conclusion, the ethanol extract of fennel leaves can be used to reduce blood sugar levels.
Management Of Immune Formation for Covid-19 Prevention Through Vaccination I Irnawati; Benny Arief Sulistyanto; Nuniek Nizmah Fajriyah
Urecol Journal. Part C: Health Sciences Vol. 1 No. 2 (2021): August-Dec
Publisher : Konsorsium LPPM Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53017/ujhs.78

Abstract

The Covid-19 disease is still very high in transmission. The total number of confirmed Covid-19 patients on October 9, 2021 is 5615 people (Pekalongan City), 7927 people (Pekalongan Regency) and 320 people (Pekalongan City), 562 people (Pekalongan Regency) died from Covid-19. The existence of a vaccine is clearly the best hope to reduce the transmission rate of the Covid-19 virus which is getting out of control. Vaccines and health education about the benefits of the Covid-19 vaccine and Post-Immunization Adverse Events (AEFI) aims to: (1) increase knowledge about the benefits of the Covid vaccine -19 to prevent the transmission of Covid-19; (2) increase public awareness to carry out the Covid-19 vaccine and not panic if AEFIs appear. The target of this community service is consisting of students and alumni of Pekajangan Muhammadiyah University, people from Pekalongan Regency, Pekalongan City, Batang Regency, Pemalang Regency and several other communities in Central Java area. The activities include registration and verification of data, screening history and simple physical examinations, as well as conducting education on Covid-19 vaccination, implementation of vaccines, submission of vaccine certificates and health education regarding AEFI. The results of this community service activity are that 1600 people have been vaccinated, know about the benefits of vaccines and AEFI. It is hoped that people who have been vaccinated will continue to apply the 5M health protocol (wearing masks, washing hands with soap, maintaining distance, limiting mobility and staying away from crowds).