Garuda - Garba Rujukan Digital

Evaluasi Penggunaan Antibiotik Empirik dan Profil Antibiotik Pasien Multi-Drug Resistant Acinetobacter baumannii di RSUP Dr. Soeradji Tirtonegoro Klaten Avanilla Fany Septyasari; Titik Nuryastuti; Ika Puspitasari
Majalah Farmaseutik Vol 16, No 2 (2020)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Resistensi antibiotik menjadi salah satu masalah yang dihadapi pada penyakit infeksi saat ini, dan salah satu bakteri yang mengalami resistensi adalah Acinetobacter baumannii. Bakteri Acinetobacter baumannii merupakan bakteri yang banyak dijumpai pada infeksi nosokomial. Penelitian ini dilakukan bertujuan untuk mengetahui antibiotik yang poten terhadap infeksi MDR Acinetobacter baumannii pada pasien rawat inap di RSUP Dr. Soeradji Tirtonegoro Klaten tahun 2016 – 2018, secara observasional dan metode penelitian yang digunakan adalah cross sectional dengan pengambilan data secara retrospective. Penggunaan antibiotik empiris pada pasien dievaluasi kesesuaiannya, kemudian antibiotik yang sesuai dianalisis prediksi kadar antibiotik, untuk mengetahui apakah antibiotik yang diberikan memenuhi kadar minimal dalam tubuh. Analisis dilakukan dengan membandingkan prediksi kadar antibiotik empiris dengan MIC antibiotik literatur (di bawah MIC atau di atas MIC) terhadap outcome klinis pasien menggunakan analisis Chi-square. Hasil penelitian menunjukkan bahwa profil antibiotik yang poten yaitu amikasin (62,9%), meropenem (56,9%), cotrimoksazol (42,5%), ampisilin-sulbaktam (29%), levofloksasin (20,7%), dan gentamisin (20,5%). Hubungan antara prediksi kadar antibiotik empiris di atas MIC terhadap outcome klinik tidak berbeda signifikan dengan di bawah MIC dibandingkan dengan outcome klinik (nilai p: 0,337).

Formulation and Physical Properties of Anti Foot Odor Spray from Lemon (Citrus limon Burm. F.) Nurul Hidayati; Maulida Kurniasari; Avanilla Fany Septyasari
Urecol Journal. Part G: Multidisciplinary Research Vol. 1 No. 1 (2021): January - June
Publisher : Konsorsium LPPM Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

Lemon (Citrus limon Burm. F.) contains essential oil in the form of limonene which has antibacterial activity against Staphylococcus epidermidis which causes foot odor. To facilitate the application, it is made in the form of a spray, because the spray has a fast-drying profile so it is easy to use. This study aims to determine the effect of variations in the concentration of lemon essential oil on the physical properties of foot odor spray and to determine the concentration of lemon essential oil which produces an anti-foot odor spray with good physical properties. Spray made with variations in the concentration of essential oils 5%, 10%, and 15%. The spray was then tested for its physical properties including organoleptic, homogeneity, pH, and viscosity tests. The results of the organoleptic test and the homogeneity test were analyzed descriptively, while the results of the pH test and viscosity test were analyzed by one-way ANOVA with a 95% confidence level. The results showed that the increase in the concentration of lemon essential oil affected the organoleptics and increased the viscosity value. The 5% concentration spray produced the best physical properties with a liquid form, cloudy white color, distinctive lemon aroma, homogeneous with a pH value of 6 ± 0, and a viscosity value of 0.53 ± 0.06 dPas.

Formulation and Physical Properties of Anti Foot Odor Spray from Lemon (Citrus limon Burm. F.) Nurul Hidayati; Maulida Kurniasari; Avanilla Fany Septyasari
Urecol Journal. Part G: Multidisciplinary Research Vol. 1 No. 1 (2021): January - June
Publisher : Konsorsium LPPM Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53017/ujmr.35

Lemon (Citrus limon Burm. F.) contains essential oil in the form of limonene which has antibacterial activity against Staphylococcus epidermidis which causes foot odor. To facilitate the application, it is made in the form of a spray, because the spray has a fast-drying profile so it is easy to use. This study aims to determine the effect of variations in the concentration of lemon essential oil on the physical properties of foot odor spray and to determine the concentration of lemon essential oil which produces an anti-foot odor spray with good physical properties. Spray made with variations in the concentration of essential oils 5%, 10%, and 15%. The spray was then tested for its physical properties including organoleptic, homogeneity, pH, and viscosity tests. The results of the organoleptic test and the homogeneity test were analyzed descriptively, while the results of the pH test and viscosity test were analyzed by one-way ANOVA with a 95% confidence level. The results showed that the increase in the concentration of lemon essential oil affected the organoleptics and increased the viscosity value. The 5% concentration spray produced the best physical properties with a liquid form, cloudy white color, distinctive lemon aroma, homogeneous with a pH value of 6 Â± 0, and a viscosity value of 0.53 Â± 0.06 dPas.

Gambaran Tingkat Pengetahuan Obat Antihipertensi Di Desa Kujon Kecamatan Ceper Kabupaten Klaten Aristhasari Putri; Avanilla Fany Septyasari; Maherawati Noni; Rheni Haryanti
CERATA Jurnal Ilmu Farmasi Vol 14 No 1 (2023)
Publisher : UNIVRSITAS MUHAMMADIYAH KLATEN

Show Abstract | Download Original | Original Source | Check in Google Scholar

Hipertensi merupakan salah satu penyebab terjadinya penyakit kardiovaskuler yang dapat menyebabkan kematian terbesar di Indonesia. Pengetahuan pasien terhadap obat antihipertensi sangat mempengaruhi pemahaman pasien sehingga menyebabkan tercapainya keberhasilan terapi. Tujuan dari penelitian ini adalah untuk mengetahui gambaran pengetahuan pasien terhadap obat antihipertensi di Desa Kujon, Ceper, Klaten. Penelitian ini merupakan penelitian deskriptif observasional, dengan teknik pengambilan data secara purposive sampling pada pasien hipertensi yang ada di Desa Kujon, Ceper, Klaten didapatkan 57 responden. Responden penelitian menerima kuisioner kemudian kuisioner tersebut dinilai, hasilnya merupakan persentase pengetahuan. Hasil penelitian menunjukkan bahwa tingkat pengetahuan responden di Desa Kujon, Ceper, Klaten terhadap hipertensi, 80,7% kategori baik, 14,04% kategori cukup; dan 5,26% kategori kurang.

A Penyuluhan PHBS (Perilaku Hidup Bersih dan Sehat) di SD Negeri 3 Kaligayam Kecamatan Wedi Kabupaten Klaten Avanilla Fany Septyasari; Nita Febriana; Norvanandhita Ardiana A.; Nur Aini Khasanah; Paramita Endang; Prima Wijayanti; Puput Kumalasari; Rini Lestari
WASATHON Jurnal Pengabdian Masyarakat Vol 1 No 02 (2023)
Publisher : Universitas Muhammadiyah Klaten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61902/wasathon.v1i02.630

Penyuluhan yang diberikan pada siswa SD Negeri 3 Kaligayam Kecamatan Wedi Kabupaten Klaten yaitu tentang Perilaku Hidup Bersih dan Sehat (PHBS). Tujuan dilakukannya penyuluhan ini yaitu meningkatkan pengetahuan dan pemahaman tentang perilaku hidup bersih dan sehat meliputi cara cuci tangan yang benar, makanan bergizi, olahraga rutin, cara menggunakan jamban dengan baik, dan membuang sampah sehingga terbentuknya perilaku hidup bersih dan sehat, sehingga dapat menurunkan angka sakit dan kematian yang disebabkan karena lingkungan yang tidak bersih dan sehat. Penyuluhan ini dilakukan dengan memberikan paparan terkait PHBS dan praktik cara cuci tangan yang baik dengan menggunakan sabun ke siswa SD Negeri 3 Kaligayam. Adapun manfaat penerapan PHBS di lingkungan sekolah yaitu terciptanya sekolah yang sehat sehingga siswa, guru, dan masyarakat lingkungan sekolah terlindungi dari berbagai gangguan dan ancaman penyakit, dapat meningkatkan semangat proses belajar mengajar yang berdampak pada prestasi belajar siswa, serta citra sekolah sebagai institusi pendidikan semakin meningkat sehingga mampu menarik minat orang tua terhadap sekolah untuk proses pembelajaran bagi anaknya.

Gambaran Tingkat Pengetahuan Obat Antihipertensi Di Desa Kujon Kecamatan Ceper Kabupaten Klaten Aristhasari Putri; Avanilla Fany Septyasari; Maherawati Noni; Rheni Haryanti
CERATA Jurnal Ilmu Farmasi Vol 14 No 1 (2023): Cerata Jurnal Ilmu Farmasi
Publisher : Universitas Muhammadiyah Klaten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61902/cerata.v14i1.761

Hipertensi merupakan salah satu penyebab terjadinya penyakit kardiovaskuler yang dapat menyebabkan kematian terbesar di Indonesia. Pengetahuan pasien terhadap obat antihipertensi sangat mempengaruhi pemahaman pasien sehingga menyebabkan tercapainya keberhasilan terapi. Tujuan dari penelitian ini adalah untuk mengetahui gambaran pengetahuan pasien terhadap obat antihipertensi di Desa Kujon, Ceper, Klaten. Penelitian ini merupakan penelitian deskriptif observasional, dengan teknik pengambilan data secara purposive sampling pada pasien hipertensi yang ada di Desa Kujon, Ceper, Klaten didapatkan 57 responden. Responden penelitian menerima kuisioner kemudian kuisioner tersebut dinilai, hasilnya merupakan persentase pengetahuan. Hasil penelitian menunjukkan bahwa tingkat pengetahuan responden di Desa Kujon, Ceper, Klaten terhadap hipertensi, 80,7% kategori baik, 14,04% kategori cukup; dan 5,26% kategori kurang.

Gambaran Pengetahuan terhadap Penggunaan Obat Tanpa Resep di Desa Karangduren Kecamatan Kebonarum Kabupaten Klaten Septyasari, Avanilla Fany; Putri, Aristhasari; Nurhaini, Rahmi; Hastikanuari, Anis Anggiara
CERATA Jurnal Ilmu Farmasi Vol 15 No 1 (2024): Cerata Jurnal Ilmu Farmasi
Publisher : Universitas Muhammadiyah Klaten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61902/cerata.v15i1.1077

Self-medication is an attempt to treat a condition or complaint based on self-diagnosed symptoms. The drugs used are non-prescription drugs, such as over-the-counter (OTC) drugs. Self-medication is one of the causes of medication errors. One of the factors in the occurrence of problems in self-medication is the lack of knowledge and understanding of the community regarding drugs and their indications. The purpose of this study was to determine the level of knowledge of the use of non-prescription drugs in the community of Karangduren Village, Kebonarum District, Klaten Regency. This research is an observational descriptive research. The sampling technique used simple random sampling method, and a questionnaire containing 15 questions including the name and content of the drug, drug efficacy, drug dosage, drug administration, and drug side effects. There were 67 respondents involved in this study. The results showed that most respondents (50.7%) had a good level of knowledge in using non-prescription drugs.

Formulasi dan Uji Sifat Fisik Krim Ekstrak Biji Lengkeng (Euphoria longan (Lour) Steud) Muchson Arrosyid; Hardhani, Salsabila Nur; Mustofa, Choiril Hana; Putri, Aristhasari; Septyasari, Avanilla Fany
CERATA Jurnal Ilmu Farmasi Vol 16 No 1 (2025): Cerata Jurnal Ilmu Farmasi
Publisher : Universitas Muhammadiyah Klaten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61902/cerata.v16i1.1673

Lengkeng termasuk kedalam tumbuhan tropis yang memiliki kandungan kimia yang salah satunya berfungsi sebagai antihiperpigmentasi kulit. Bagian tumbuhan yang belum banyak dimanfaatkan adalah bagian biji. Tujuan penelitian ini yaitu untuk mengetahui sifat fisik formula krim biji lengkeng dengan variasi konsentrasi 1%, 2%, dan 3%. Metode pengujian yang dilakukan meliputi uji organoleptis, uji tipe krim, uji pH, uji homogenitas, uji daya sebar, dan uji viskositas. Hasil menunjukkan bahwa ketiga formula ekstrak biji lengkeng menghasilkan uji organoleptik dengan hasil krim kental berwarna coklat, uji pH yang memenuhi standar, uji tipe emulsi M/A, uji homogenitas krim homogen, uji daya sebar memenuhi standar, dan uji viskositas juga memenuhi standar.

Patient adherence and factors associated with short-term oral antibiotic use for acute respiratory infections (ISPA) in Wedi primary health care Putri, Aristhasari; Septyasari, Avanilla Fany; Ridhwan, Adib Muhammad
Borobudur Pharmacy Review Vol. 5 No. 2 (2025): August-Dec
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/bphr.v5i2.14513

Upper respiratory tract infection (URTI) is a common illness in Indonesia caused by microorganisms, caused by microorganisms that affect the upper respiratory tract. Short-term antibiotic therapy is frequently prescribed, but many patients do not adhere to this treatment. Non-compliance often occurs because patients feel better, forget to take their medication, or do not follow the prescribed regimen properly. This can lead to poor clinical outcomes and an increased risk of bacterial resistance. This study was conducted to to assess the level of adherence and contributing factor among URTI patients to short-term oral antibiotic therapy. A cross-sectional research design was employed, utilizing a structured questionnaire for data collection. The sampling method applied was purposive sampling, which included a cohort of 31 patients with URTI who were prescribed short term antibiotics. The results showed that 77.4% of respondents were compliant, while 22.6% were non-compliant. Factors that significantly associated with adherence included educational level and occupation (p < 0.05), while age did not show a significant relationship (p > 0.05). Another factors influencing non-adherence included inadequate information provided by healthcare professionals, busy schedules, premature discontinuation of therapy due to perceived recovery, lack of family support, and difficulty swallowing medication. Pharmacists can play a significant role in improving compliance by providing clear information and utilizing reminder tools to assist patients in taking their medication as prescribed.

Evaluasi Komparatif Asam Sitrat Pada Beberapa Kultivar Mangga Lokal (Mangifera indica L.) dengan Metode Titrasi Alkalimetri Choiril Hana Mustofa; Elsa Epilia Duri; Avanilla Fany Septyasari; Aristhasari Putri
CERATA Jurnal Ilmu Farmasi Vol 17 No 1 (2026): Cerata Jurnal Ilmu Farmasi
Publisher : Universitas Muhammadiyah Klaten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61902/cerata.v17i1.2449

Citric acid is an organic secondary metabolite found in fruit and is important in determining the sensory profile and biochemical stability of mango (Mangifera indica L.). This observational study aimed to quantitatively measure the prevalence of citric acid in three local mango varieties: Harumanis, Indramayu, and Manalagi. The methodology employed included qualitative identification through a precipitation reaction with calcium chloride (CaCl₂) and quantitative determination using an alkalimetric method. Qualitative test results on all three samples confirmed the presence of citric acid in all samples through the formation of calcium citrate precipitates. Quantitative analysis showed that the average citric acid content in Harumanis mangoes was 0.69%, Indramayu mangoes 0.98%, and Manalagi mangoes 0.92%. These findings indicate that the Indramayu variety has the highest citric acid content, which implies a potential longer shelf life compared to other varieties.

Title

Found 14 Documents
Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title Search

Found 14 Documents Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title

Found 14 Documents
Search