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All Journal Jurnal Riset Kefarmasian Indonesia SITAWA : Jurnal Farmasi Sains dan Obat Tradisional
Mega Yulia
Akademi Farmasi Imam Bonjol Bukittinggi
Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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PENGARUH PERBEDAAN SUHU PENGERINGAN TERHADAP AKTIVITAS ANTIOKSIDAN DAUN JARAK PAGAR (Jatropha curcas L) rahmayulis; Mega Yulia; Riflyani
SITAWA : Jurnal Farmasi Sains dan Obat Tradisional Vol. 3 No. 1 (2024): SITAWA : Jurnal Farmasi Sains dan Obat Tradisional
Publisher : LPPM Akademi Farmasi Imam Bonjol Bukittinggi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62018/sitawa.v3i1.86

Abstract

Jatropha plant is a plant that contains secondary metabolites, including steroids, phenolics, flavonoids and saponins. Jatropha plants are also known to have antioxidant activity. This study aims to determine the best drying temperature for the antioxidant activity test of jatropha leaves. The antioxidant activity test was carried out by drying test jatripha leaves using ovens with different temperatures, namely temperatures of 40oC, 50oC and 60oC wich was then tested for antioxidant activity using the DPPH method (2-2 diphenyl-picrylhydrazil) using a UV-Vis Spectrophotometer. The results of antioxidant activity testing in Jatropha were obtained, at drying temperature 40oC IC50 value of 1,868.87 ppm, temperature 50oC IC50 value of 1,116.97 ppm and temperature 60oC IC50 value of 319,90 ppm. From the results of the study, it can be concluded that drying samples using an oven at 60oC has a better IC50 value than drying at 40oC and 50oC, which is 319,90 ppm and classified as weak antioxidants.
UJI AKTIVITAS SITOTOKSIK EKSTRAK METANOL BUAH KETUMBAR (Coriandrum sativum Linn) TERHADAP ARTEMIA SALINA LEACH DENGAN UJI BSLT (Brine Shrimp Lethality Test) Mega Yulia; Rani Anggraini; Farizal Farizal
Jurnal Riset Kefarmasian Indonesia Vol. 2 No. 3 (2020): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v2i3.72

Abstract

Coriander is a common herb can be used as traditional medicine. One of the expected benefits of Coriander fruits is an anti-cancer. This study aims to determine the cytotoxic activity of Coriander extract (Coriandrum sativum Linn) on shrimp larvae (Artemia salina Leach) with the BSLT (Brine Shrimp Lethality Test) method. Coriander fruits was extracted using methanol solvent and maceration method, then concentrated it with a rotary evaporator until a thick extract. Cytotoxic activity test used methanol extract with several concentration : 1,000 ppm, 100 ppm, 10 ppm, and 1 ppm. The result of this research reveal that methanol extract of Coriander fruits has cytotoxic activity with LC50 value is 32.35 ppm.
Co-Authors Farizal Farizal Rahmayulis Rani Anggraini Riflyani