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All Journal JFL : Jurnal Farmasi Lampung
Novita Tri Wahyuni
Program Studi Farmasi Universitas Tulang Bawang
Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology Public Health

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POTENSI INTERAKSI OBAT PADA PASIEN GASTRITIS DI PUSKESMAS RAWAT INAP WAY KANDIS BANDAR LAMPUNG TAHUN 2020 Lilik Koernia Wahidah; Novita Tri Wahyuni; Cahya Rizky Amaliana
JFL : Jurnal Farmasi Lampung Vol. 10 No. 2 (2021): JFL : Jurnal Farmasi Lampung
Publisher : Program Studi Farmasi Universitas Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v10i2.702

Abstract

ABSTRACT Gastritis is an inflammatory process in the mucous and sub-mucous layers of the stomach. The use of several drugs simultaneously facilitates the occurrence of drug interactions that are part of the Drug Related Problem (DRPs). This study aims to determine the potential for drug interactions in gastritis patients at the Puskesmas Rawat Inap Way Kandis Bandar Lampung in 2020. The research method carried out is observational research with a descriptive design taken retrospectively. The results of the study based on gender showed that there were 34 male patients (40.5%) and 50 female patients (59.5%). Then, based on the age group of 17-25 years, there were 26 patients (31%), aged 26-35 years as many as 16 patients (19%), aged 36-45 as many as 19 patients (22.6%), aged 46-55 as many as 13 patients (15.5%), aged 56-65 as many as 5 patients (6%), and aged >65 years as many as 5 patients (6%). The most use of gastritis drugs are antacids (92.8%), omeprazole (21.4%), ranitidine (15.1%). Drug interactions based on pharmacokinetic mechanisms were 20 cases (58.8%), and pharmacodynamic mechanisms were 14 cases (41.1%). Severity, 18 cases (52.9%) minor, 14 cases (41.1%) moderate, and 2 cases (5.8%) major. It was concluded that the potential drug interactions that experienced the incidence of drug interactions were 27 samples (32.1%) and 57 samples (67.8%) did not experience drug interactions.  Keywords : Antacids, DRPs, Drug Interactions, Gastritis, Omeprazole, Ranitidine
IDENTIFIKASI DRUG RELATED PROBLEMS (DRPs) PENGGUNAAN ANTIHIPERTENSI PASIEN HIPERTENSI DI RSU AZZAHRA KALIREJO LAMPUNG TENGAH Lilik Koernia Wahidah; Novita Tri Wahyuni; Desiamti Ughfiroh
JFL : Jurnal Farmasi Lampung Vol. 11 No. 1 (2022): JFL : Jurnal Farmasi Lampung
Publisher : Program Studi Farmasi Universitas Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v11i1.715

Abstract

A person is diagnosed with hypertension if there is an increase in systolic blood 140 mmHg and diastolic blood pressure 90 mmHg. Treatment of hypertension aims to reduce morbidity and mortality. Hypertensive patients receiving polypharmacy pharmacological therapy are at risk of developing DRPs. The purpose of this study was to identify the incidence of Drug Related Problems (DRPs) in the use of antihypertensives in hypertensive patients at Azzahra Kalirejo General Hospital, Central Lampung in 2021. This study was non-experimental with a retrospective descriptive design, then identified using the classification of DRPs according to Robert J. Cipolle EL. Pharmaceutical Care Practice and Medscape and Drug Interaction Chacker applications to identify drug interactions, and use the Medication Possession Ratio (MPR) formula to identify patient non-compliance. Based on the results of research at Azzahra Kalirejo General Hospital, Central Lampung, of the 135 samples that met the inclusion criteria, 80% of the samples experienced DRPs. Based on gender characteristics, there were 50.37% male and 49.62% female with 0% of patients aged <25 years, age 26-45 years 30.3%, age 46-65 years 57.8% and age > 65 years 11.8%. The most widely prescribed antihypertensive drug was furosemide as much as 42.2%, the most antihypertensive combination was a combination of two drugs as much as 57%. The most use of non antihypertensive drugs is PPI and analgesics as much as 12.8%. Cases of DRPs requiring additional therapy were 1.9%, drug therapy was not necessary 7.4% cases, inappropriate drugs 4.6% cases, doses too low and high in 0% cases, drug interactions were 77.8% with major severity 11.7%, minor 34.5% cases and moderate as many as 53.7%, patient non-compliance with DRPs occurred in 51.9% cases.  Keywords:  Antihipertensive, DRPs, Furosemide, Hypertension
STUDI FARMAKOVIGILAN OBAT ANTIHIPERTENSI PADA PASIEN HIPERTENSI RAWAT JALAN DI DR. A. DADI TJOKRODIPO BANDAR LAMPUNG PERIODE OKTOBER–NOVEMBER 2021 Lilik Koernia Wahidah; Novita Tri Wahyuni; Dion Yongtama
JFL : Jurnal Farmasi Lampung Vol. 11 No. 2 (2022): JFL : Jurnal Farmasi Lampung
Publisher : Program Studi Farmasi Universitas Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v11i2.814

Abstract

Hypertension, also known as high blood pressure, is systolic pressure140 and diastolic pressure 80 mmHg. The more blood pressure is pumped by the heart and the narrower the arteries, the higher the blood pressure. This study aims to determine the occurrence of adverse drug reactions in hypertensive patients in RSD DR. A. Dadi Tjokrodipo Bandar Lampung. This research is a descriptive research with total sampling method. Collecting data by looking at the patient's medical record data. The results showed that the female sex was more dominant in suffering from hypertension, namely 20 female patients (62.5%) and 12 male patients (37.5%). The highest age characteristics were found in the age range of 46-55 years as many as 14 patients (43.75%). The most characteristic of hypertension was in the case of stage 2 hypertension with a total of 17 patients (53.12%). The highest pattern of drug use was amlodipine (37.5%). The incidence of drug interactions was 10 cases (31.25%) with minor severity. The highest incidence of ADR was in the "moderately probable" 1-4 with a total of 15 cases (46.87%). Keywords: ADR, hypertension, drug interactions, antihypertensive drugs
HUBUNGAN PENGETAHUAN DAN PERILAKU IBU DENGAN KEJADIAN ISPA PADA BALITA DI PUSKESMAS KALIREJO KECAMATAN NEGERI KATON KABUPATEN PESAWARAN Akhmad Rokiban; Novita Tri Wahyuni; Anita Purnama Sari
JFL : Jurnal Farmasi Lampung Vol. 12 No. 1 (2023): JFL : Jurnal Farmasi Lampung
Publisher : Program Studi Farmasi Universitas Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v12i1.980

Abstract

Acute Respiratory Infection (ARI) is an upper or lower respiratory tract disease, where an acute infection process that lasts for 14 days, is caused by microorganisms that attack one or more parts of the respiratory tract, from the nose to the alveoli. This study aims to determine the relationship between knowledge and behavior of mothers with the incidence of ARI in children under five at the Kalirejo Public Health Center Negeri Katon District Pesawaran Regency. This type of research is descriptive observational. This research was conducted in June. The sample in this study was 100 respondents, the sampling technique in this study was accidental sampling, in this study the validity and reliabilitas Based on the chi-square results between knowledge and maternal behavior, a value (p value = 0.020) was obtained, maternal knowledge with the incidence of ARI was obtained (p value = 0.000), maternal behavior with ARI incidence was obtained (p value = 0.041). From this study, it can be concluded that the significance value < 0.05 indicates that there is a relationship between knowledge and maternal behavior, knowledge relationship with the incidence of ARI, and behavior with the incidence of ARI. Keywords: Incidence of ARI, Knowledge, Behavior
EVALUASI PENGGUNAAN OBAT HIPERTENSI PADA PASIEN RAWAT JALAN DI RUMAH SAKIT BHAYANGKARA POLDA LAMPUNG TAHUN 2020 Lilik Koernia Wahida; Novita Tri Wahyuni; Niluh Suastini
JFL : Jurnal Farmasi Lampung Vol. 12 No. 1 (2023): JFL : Jurnal Farmasi Lampung
Publisher : Program Studi Farmasi Universitas Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v12i1.999

Abstract

ABSTRACT Hypertension is a condition in which a person experiences an increase in blood pressure above normal, which is higher than 140 mmHg systolic or 90 mmHg diastolic. Hypertension plays a very important role in causing the death of thousands of people, due to its dangerous side-effects, such as stroke, heart attack, heart failure, and kidney failure. The purpose of this study is to evaluate the use of hypertension drugs in outpatient hypertension patients at Bhayangkara Polda Hospital Lampung. Evaluation of drug use is a quality assurance process in the use of drugs in hospitals aimed at ensuring the drugs used are appropriate, safe and effective. The data collection technique in this study began with the selection process of outpatient medical records who had a primary diagnosis of hypertension. The population in this study were all patient medical records at the Bhayangkara Polda Lampung Hospital in the period of 2020, the use of hypertension drugs based on the right patient was 103 patients, which was 100% correct, the use of Antihypertensive drugs based on the right indication was 103 patients, which was 100% correct. the use of antihypertensive drugs based on the right drug was 82 patients with a percentage (79.61%) of the right drug and as many as 21 patients (20.39%) the wrong drug because the drug given was not in accordance with the standard used, the use of antihypertensive drug was based on the right dose as much as 103 patients were 100% on the right dose, because the dose given was in accordance with the range of antihypertensive drug therapy based on JNC VIII. Keywords: hypertension, drug evaluation, drug use.
Co-Authors Anita Purnama Sari Cahya Rizky Amaliana Desiamti Ughfiroh Dion Yongtama Lilik Koernia Wahidah Niluh Suastini Rokiban, Akhmad