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All Journal The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy

Marcellus Simadibrata

Division of Gastroenterology, Department of Internal Medicine, Faculty of Medicine University of Indonesia/Dr. Cipto Mangunkusumo General National Hospital, Jakarta

Author-ID : 5436097

Medicine & Pharmacology

Published : 4 Documents Claim Missing Document

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Articles

Adult Ileocecal Intussusception: A Case Report and Review Randy Adiwinata; Sheila Adiwinata; Emerson Patulahon Simatupang; Willy Brodus Uwan; Marcellus Simadibrata
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 20, No 1 (2019): VOLUME 20, NUMBER 1, April 2019
Publisher : The Indonesian Society for Digestive Endoscopy

Intussusception is a rare cause of bowel obstruction in adult patients, it represents for five percent of all age intussusception. Several different aspects were found between adult and pediatric intussusception. We report a case of 39-year-old male with bowel obstruction due to ileocecal intussusception, which firstly diagnosed as acute appendicitis. Unlike pediatric intussusception which usually manifest as classical triad signs, unspecific symptoms of adult intussusception may become diagnostic challenge. Imaging modalities such as plain abdominal radiograph and ultrasonography may aid the preoperative diagnosis in the rural hospital setting. Prompt management which involved surgical approach is warranted to prevent further complications.

Recurrent Acute Pancreatitis as A Manifestation of Sphincter of Oddi Dysfunction Ira Laurentika; Ari Fahrial Syam; Marcellus Simadibrata
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 17, No 1 (2016): VOLUME 17, NUMBER 1, April 2016
Publisher : The Indonesian Society for Digestive Endoscopy

Recurrent acute pancreatitis (RAP) is defined as two or more occurance of acute pancreatitis with no evidence of underlying chronic pancreatitis. Prevalence of RAP varied from 10-30%. One of the postulated mechanism of this condition is sphincter of Oddi dysfunction (SOD) which is a clinical biliary pain syndrome or acute pancreatitis (AP) due to pancreatobiliary obstruction at the level of sphincter of Oddi. We reported a 29-year-old female patient who came to Cipto Mangunkusomo Hospital regarding upper quadrant abdominal pain with previously well documented history of AP in the last six months before admission. Laboratory findings showed elevated pancreatic enzyme level which was consistent with AP. The patient underwent magnetic resonance cholangio-pancreatography (MRCP) and endoscopic ultrasound (EUS) examination and both of the results showed dilatation of pancreatic duct which suggested SOD. Due to the lack of further diagnostic modality, manometry was not performed on this patient. However, after excluding other possible etiology of SOD, the patient underwent endoscopic retrograde cholangio-pamcreatograhy (ERCP) and sphincterotomy was performed. The signs and symptoms of AP was relieved after sphincterotomy and not yet recurred.

The Use of Immunochemical Fecal Occult Blood Test as Colorectal Cancer Screening Tool in Asymptomatic Population in Indonesia Murdani Abdullah; Hayatun Nufus; Ari Fahrial Syam; Dadang Makmun; Marcellus Simadibrata; Abdul Aziz Rani
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 15, No 1 (2014): VOLUME 15, NUMBER 1, April 2014
Publisher : The Indonesian Society for Digestive Endoscopy

Background: Colorectal cancer is the fourth leading cause of cancer-related mortality worldwide. Earlydetection of colorectal cancer is necessary in term of increasing survival. Immunochemical fecal occult bloodtest (I-FOBT) is one of the simple and inexpensive screening modality that can be used widely. No data has been available yet regarding the usage of I-FOBT in Indonesia. This study is a prevalence study of I-FOBT in asymptomatic population in Indonesia. Method: A cross sectional study was conducted in asymptomatic population visiting five public health service centers in Depok district, West Java, Indonesia. This study was performed from January to March 2012. Casereport form and I-FOBT kit were used to assess and screen the patients. Statistic analysis was performed usingChi-square test. Results: The prevalence of positive I-FOBT was almost equally distributed among age group. Femaledominated whole patients 202 (72.7%). Most of them had middle to low education level 116 (41.7%). As manyas 50.7% patients had normal body mass index. We had 11 (4%) patients with positive result of I-FOBT. Conclusion: Prevalence of positive result of I-FOBT in asymptomatic population in Indonesia was 4%.Further studies were needed to confirm sensitivity and specifity of I-FOBT in Indonesia.Keywords: colorectal cancer, immunochemical fecal occult blood test (I-FOBT), early detection

The Effect of Zinc Supplementation in Adult Patients with Acute Diarrhea Deskian Kostermans; Marcellus Simadibrata; Irsan Hasan
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 15, No 2 (2014): VOLUME 15, NUMBER 2, August 2014
Publisher : The Indonesian Society for Digestive Endoscopy

Background: Acute diarrhea is a common problem in developing country such as Indonesia with quite high morbidity andmortality rate. It was revealed that the level of zinc deficiency in adult acute diarrhea patients in several hospitals in Jakarta was 69.3%. Although zinc has been proven to be beneficial in the treatment of acute diarrhea in pediatric patients, the effect of zinc supplementation is not fully understood. The objective of this study was to discover the effectiveness of zinc supplementation as an adjuvant therapy in acute diarrhea for adult patients.Method: A double blind randomized controlled trial was done to discover the effect of zinc supplementation to the duration, signs and symptoms on acute diarrhea in hospitalized adults patients in Pertamina Central Hospital, Jakarta from January to December 2013. The data was analyzed using Chi-square test to compare the duration of diarrhea and general linear model (GLM) to assess changes of the symptoms accompanying diarrhea.Results: Data analysis from 84 patients, 30 males (19 zinc, 11 placebo) and 54 females (23 zinc, 31 placebo) with p = 0.111 showed that zinc supplementation significantly reduced the duration of acute diarrhea (p = 0.027) and nausea (p = 0.032). In addition there is a tendency of improvement in several acute diarrhea associated symptoms.Conclusion: Zinc supplementation significantly reduces the duration of diarrhea, nausea, as well as improving some symptoms accompanying acute diarrhea. Keywords: zinc supplementation, acute diarrhea, adult patient

Co-Authors Abdul Aziz Rani Ari Fahrial Syam Dadang Makmun Deskian Kostermans Emerson Patulahon Simatupang Hayatun Nufus Ira Laurentika Irsan Hasan Murdani Abdullah Randy Adiwinata Sheila Adiwinata Willy Brodus Uwan

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