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Seroepidemiology and risk factors of Hepatitis B and C virus infections among drug users in Jakarta, Indonesia Gani, Rino A.; Budihusodo, Unggul; Waspodo, Agus; Lesmana, L. A.; Hasan, Irsan; Akbar, Nurul; Noer, H. M.S.
Medical Journal of Indonesia Vol 11, No 1 (2002): January-March
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (845.285 KB) | DOI: 10.13181/mji.v11i1.51

Abstract

The number of drug users is markedly increased in recent times. Data were collected consecutively in Cipto Mangunkusumo Hospital and Mitra Menteng Abadi Hospital in Jakarta. HBsAg were examined using reverse passive hemaglutination assay (RPHA) and anti-HCV with dipstick method; both were from the laboratoium Hepatika, Mataram, Indonesia. In a 5 month period (March - August 1999) there were 203 cases of drug users. Most of them were male ( 185 cases or 91.1%) with a mean age of 21.2 ± 4.3 years. Mean age in starting to use the drug was 18.8 ± 4.0 years. The prevalence of anti-HCV and HBsAg positivity were 74.9% (151 cases) and 9.9% (19 cases), respectively. The prevalence of double infection was 7.4% (15 cases). Injection drug users (IDU) were 168 cases (84%). Extramarital sex was done by 62 cases (30.5%), but only 16 cases (8%) with more than one partner. Tattoo was found in 32 cases ( 15.8%). Multivariate analysis revealed that lDU and tattoo were the risk factors for anti-HCV positivity, with the OR of 9.15 (95% CI 3.28-5.53) and 13.24 (96% CI 1.6 - 109.55), respectively. No significant medical risk factor could be identified for HBsAg positivity. Double infection of HBV and HCV was found in 15 cases (7.4%). We concluded that the prevalence of HBV, HCV infection and double infection of HBV - HCV in drug users were high, with tattoo and injection drug usage as risk factors for hepatitis C virus infection. (Med J Indones 2002; 11: 48-55)Keywords: HBsAg, Anti-HCV, tattoo, injection drug users
Choline-deficient High-fat Diet-induced Steatohepatitis in BALB/c Mice Saut Horas Hatoguan Nababan; Seruni Tyas Khairunissa; Erni Erfan; Nafrialdi Nafrialdi; Ening Krisnuhoni; Irsan Hasan; Rino Alvani Gani
Molecular and Cellular Biomedical Sciences Vol 5, No 2 (2021)
Publisher : Cell and BioPharmaceutical Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21705/mcbs.v5i2.193

Abstract

Background: Non-alcoholic steatohepatitis (NASH) is an expanding cause of chronic liver disease worldwide, including Indonesia, with higher risk progression to cirrhosis and hepatocellular carcinoma. Preclinical experiments using several mice models have been conducted to clarify its complex pathogenesis. This study was designed to investigate whether BALB/c mice on a choline-deficient high-fat diet can be used as a model for NASH. Materials and Methods: BALB/c male mice were fed choline-deficient L-amino acid-defined high-fat diet (CDAHFD) or a standard diet for six weeks. The body and liver weights, liver histology, and plasma biochemistry were analyzed. The relative expression levels of tumor necrosis factor (TNF)α, transforming growth factor (TGF)β1, collagen-1α1 (COL1α1), glutathione peroxidase 1 (GPx1), and uncoupling protein 2 (UCP2) genes in the livers were analyzed using a two-step real time-polymerase chain reaction. Liver fatty acids composition was analyzed using gas chromatography with flame ionization detector (GC-FID). Results: CDAHFD induced steatohepatitis in BALB/c mice with increased plasma levels of alanine aminotransferase. The liver of CDAHFD-fed BALB/c mice showed upregulated relative expression levels of TNFα, TGFβ1, COL1α1, GPx1, and UCP2 genes. The liver fatty acid analysis showed a significant accumulation of saturated fatty acids (SFAs) and an increased ratio of n-6/n-3 polyunsaturated fatty acids (PUFAs) in the livers of CDAHFD-fed BALB/c mice. Conclusion: This study suggests that CDAHFD can induce steatohepatitis in BALB/c mice and therefore may be used as NASH mice model.Keywords: steatohepatitis, fatty liver, choline-deficient high fat diet, BALB/c 
Kekuatan genggam tangan, skor Child Pugh, dan massa otot pada pasien dengan sirosis hati Amanda Trixie Hardigaloeh; Rino Alvani Gani; Irsan Hasan; Andri Sanityoso Sulaiman
Jurnal Gizi Klinik Indonesia Vol 14, No 3 (2018): Januari
Publisher : Minat S2 Gizi dan Kesehatan, Prodi S2 IKM, FK-KMK UGM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijcn.34302

Abstract

Background: Malnutrition is independent factor related to morbidity, mortality and high cost of treatment in liver cirrhosis. Hand grip strength (HGS) is one of the method use for malnutrition detection and prognosis evaluation. The correlation of HGS with liver function (Child Pugh score) and muscle mass is controversial. These important evaluation is not yet avalaible in Indonesia.Objective: Aim of this study is to assess the role of HGS measurement in malnutrition and its correlation with liver function and muscle mass.Method: This is a cross-sectional study in liver cirrhosis patients at Hepatobiliary Clinic of Cipto Mangunkusumo Hospital from February to June 2015. Nutritional status was assessed by HGS. Muscle mass was obtained from bioimpedance. Data were analyzed using Spearman correlation test.Results: There were 115 patients liver cirrhosis at Hepatobiliary Clinic of Cipto Mangunkusumo Hospital, 112 patients who fit the inclusion criteria, consisted of 79 men and 33 women with mean age 54.15±10.55 years, median Child Pugh score 6 (5-13) with median HGS 26 (11-50) kgF, mean muscle mass 44.43±8.12 kg. The median intake of energy 1334.82 (604.75-3023.7) kkal, median protein 45.87 (19-114.5) gram. Prevalence of malnutrition according HGS was 33%. Hand grip strength is not correlated with Child Pugh score (p=0.046; r=-0.19) however it is correlated with muscle mass (p<0.00; r=0.70).Conclusion: There are 33% malnutrition cases based on HGS in out patient liver cirrhosis. There is no correlation between HGS with Child Pugh score however HGS is correlated with muscle mass in liver cirrhosis.
Drug-Induced Liver Injury – Tantangan dalam Diagnosis Imelda Maria Loho; Irsan Hasan
Cermin Dunia Kedokteran Vol 41, No 3 (2014): Farmakologi
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v41i3.1152

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Jejas hati imbas obat (drug-induced liver injury, DILI), atau hepatotoksisitas imbas obat, merupakan jejas hati yang disebabkan oleh pajanan terhadap obat atau agen non-infeksius. Jejas yang ditimbulkan oleh obat bervariasi, mulai dari tidak bergejala, ringan, hingga gagal hati akut yang mengancam nyawa. Insidens hepatotoksisitas imbas obat terbilang rendah, yaitu antara 1 dari 10.000 sampai 1 dari 100.000 pasien, tampaknya karena sulitnya diagnosis dan angka pelaporan yang masih rendah. Kunci penting diagnosis DILI adalah pajanan obat harus terjadi sebelum onset jejas hati dan penyakit lain yang dapat menyebabkan jejas hati harus disingkirkan. Selain itu, jejas hati akan membaik bila penggunaan obat tertentu dihentikan dan jejas hati dapat terjadi lebih cepat dan lebih berat pada pajanan berikutnya, khususnya bila jejas hati tersebut terjadi akibat proses imunologis.Drug-induced liver injury or drug-related hepatotoxicity is injury to the liver caused by exposure to a drug or another noninfectious agent. The clinical signs could vary from very mild condition without any clinical symptoms to severe and life-threatening acute liver failure. Drug-related hepatotoxicity has a low reported incidence, ranging from 1 in 10.000 and 1 in 100.000 patients, but its true incidence may be higher because of difficulties in detection or diagnosis and underreporting. Key elements in assessing cause in the diagnosis of drug-related hepatotoxicity were : Exposure to a drug must precede the onset of liver injury. Other disease should be ruled out. Condition may improve when the drug is stopped and may recur more rapidly and severely on repeated exposure, especially if immunological process is involved. 
Effect of L-ornithine-L-aspartate Therapy on Low-Grade Hepatic Encephalopathy in Patients with Liver Cirrhosis Martha Iskandar; Irsan Hasan; Unggul Budihusodo
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 12, NUMBER 1, April 2011
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/121201138-43

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Background: Minimal hepatic encephalopathy (MHE) is an abnormal condition of psychometric testing before hepatic encephalopathy (HE) condition reducing quality of life and survival rate. Impractical instrument, the psychometric hepatic encephalopathy score (PHES), has been recommended in diagnosing MHE. The new critical flicker frequency (CFF) has good precision and accuracy for diagnosing MHE. Oral L-ornithine-L-aspartate (LOLA) may increase ammonia detoxification. The aim of this study was to recognize the effect of oral LOLA on low-grade HE by investigating the mean value of CFF. Method: We included 31 patients with liver cirrhosis and low-grade HE (MHE, HE grade 1 and 2) at the outpatient clinic of hepatology, Cipto Mangunkusumo hospital between November 2009 and March 2010. It was a double-blind, randomized, placebo-controlled clinical trial. Oral LOLA was administered in a dose of 18 g/day, 3 times daily for 14 consecutive days. At the end of the study, there were 27 cirrhotic patients with CFF value 38 Hz; 14 patients had received LOLA and 13 patients had placebo. Statistic analysis was performed by using the Mann-Whitney U test. Results: The mean value of CFF in LOLA group after treatment (39.3 Hz) was significantly different than the placebo group (36.04 Hz); (p = 0.027). Ammonia level decreased in LOLA group from 118.7 into 109.1 µ mol/L. In placebo group, it increased from 106.9 into 147.5 µ mol/L with p = 0.275 (before); p = 0.052 (after). Conclusion: Oral LOLA may improve the value of CFF and is likely to decrease blood ammonia level in patients with low-grade HE.   Keywords: low-grade hepatic encephalopathy, oral LOLA, CFF improvement, ammonia detoxification
Update 2013: the Role of Probiotic in Non-alcoholic Fatty Liver Disease, an Evidence Based Approach Alvin Nursalim; Irsan Hasan
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 14, NUMBER 2, August 2013
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (439.33 KB) | DOI: 10.24871/1422013103-108

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During the last two decades, non-alcoholic fatty liver disease (NAFLD) has been a topic in many discussions. The major risk factors for NAFLD is metabolic syndrome, which include obesity, insulin resistance andhypertension. Beside insulin resistance, oxidative stress has been linked with the disease. There is accumulating evidence that intestinal bacterial overgrowth plays an important role in NAFLD pathogenesis. Intestinal bacteria influence the progression of NAFLD through endogenous ethanol production and cytokine that would eventually induce hepatic oxidative stress. Probiotic intervene pathogenic intestinal flora so it is a potential treatment for NAFLD. Many animal studies documented the beneficial effect of probiotic in NAFLD. Probiotic reduce hepatic inflammation, reduce hepatic steatosis and improve insulin resistance. There is still limited human studies upon this topic. However, preliminary result showed potential role of probiotic in NAFLD treatment. Probiotic is safe, cheap and widely available therefore it is a promising new approach for NAFLD therapy. Upcoming study would hopefully provide firm foundation regarding the use of probiotic for NAFLD on human.Keywords: NAFLD, probiotic, metabolic syndrome
Conformity between Ileoscopy Appearance with Terminal Ileum Histopathology Appearance in Normal Colonoscopy Chronic Diarrhea Patients Indra Marki; Ari Fahrial Syam; Irsan Hasan
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 15, No 2 (2014): VOLUME 15, NUMBER 2, August 2014
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (122.424 KB) | DOI: 10.24871/152201488-92

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Background: Chronic diarrhea is one of the most common problem in gastroenterology cases. Ileoscopy is one of the modalities to determine the etiology of chronic diarrhea by normal colonoscopy appearance. Recently, there is still controversy in the need of this examination in normal macroscopic appearance. The aim of this study is to study the conformity of histopathology abnormalities with ileoscopy appearance in chronic diarrhea patients with normal colonoscopy.Methods: This study uses cross sectional study design by collecting 60 medical record data in several hospitals in Jakarta in the period of 1 January 2005 to 31 December 2011. Diagnostic test between ileoscopy and histopathology is performed by histopathology examination as a gold standard.Results: Study results revealed conformity between both examinations for 93.33%. Sensitivity value of ileoscopy examination compared to histopathology as a gold standard was 94%, specificity 90%, positive predictive value 97.9%, and negative predictive value 75%.Conclusion: Ileoscopy examination in chronic diarrhea patients and normal colonoscopy showed similar results with histopathology examination. Keywords: Ileoscopy, histopathology, conformity, chronic diarrhea
Non-endoscopic Examination as Predictor of Varices Degree in Liver Cirrhosis Patients Who have Experienced Esophageal Variceal Bleeding Paulus Kusnanto; Marcellus Simadibrata; Irsan Hasan
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 12, NUMBER 1, April 2011
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/121201115-22

Abstract

Background: Standard diagnosis for determining the degree of varices is by endoscopy. However, sometimes there are obstacles in the implementation of endoscopy. Based on the factors, we need to know the parameters of non-endoscopic examination which include ascites, splenomegaly, thrombocytopenia, Child-Pugh, portal vein diameter as a predictor of the degree of liver cirrhosis patients with varices who have experienced esophageal variceal bleeding. Method: The study design was cross-sectional study. The study was conducted on hospitalized patients in Cipto Mangunkusumo hospital, Gatot Subroto hospital, and Kraton hospital from September 2008 to November 2009. The patients were liver cirrhosis patients with history of upper gastrointestinal bleeding, no present bleeding, and hemodynamically stable. Examination of predictor factors in the patients such as ascites, splenomegaly, thrombocytopenia, Child-Pugh and portal vein diameter were done. Statistical analysis was performed with student’s t-test, Mann-Whitney test, and stepwise multivariable logistic regression. Results: The study involved 44 patients with liver cirrhosis who have esophageal variceal bleeding. Based on the results of endoscopic examination, large varices (F3) were found in 21 (47.73%) patients, small varices (F1 F2) in 23 (52.27%) patients, located on the distal esophagus extending to the medial (86.4%), with red color sign present (54.5%). Results of non-endoscopic examination such as splenomegaly, ascites, thrombocytopenia, portal vein diameter and Child-Pugh score was known not to be associated with the degree of esophageal varices (p 0.05). Conclusion: Non-endoscopic examination was not related to the degree of varices in liver cirrhosis patients who have experienced esophageal variceal bleeding. Keywords: esophageal variceal bleeding, liver cirrhosis, predictor factors, endoscopic criteria
Factors Found on the First Variceal-Bleeding Episode in Liver Cirrhosis Patients with Portal Hypertension Arnold Hasahatan Harahap; Dadang Makmun; Irsan Hasan
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 11, NUMBER 1, April 2010
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/111201015-18

Abstract

Background: The dietary protein restriction that was commonly recommended to hepatic encephalopathy (HE) patients, often leads to malnutrition, whereas malnutrition can deteriorate cirrhosis prognosis. The aims of this study were to find out encephalopathy improvement that was measured by critical flicker frequency (CFF) test and nutritional status by measuring prealbumin level after L-Ornithine L-Aspartate (LOLA) treatment with adequate calories and protein intake in patients with HE. Method: Patients with liver cirrosis who visited Cipto Mangunkusumo hospital on June-October 2009 was evaluated by CFF test using HEPAtonormTM device. Encephalopathy was defined when CFF 39 Hz. Nutritional status was measured by the mid-arm muscle circumference (MAMC) and was stated as malnutrition when the MAMC was below the 15th percentile. Patients had been treated by 3 x 6 mg LOLA granules for 2 weeks, and adequate calories and protein intake with branched-chain amino acid (BCAAs) substitution. The change of encephalopaty was evaluated by the CFF test and the nutritional status by measuring prealbumin blood level. Results: There were 17 patients with liver cirrhosis who fulfilled the inclusion criteria. The mean CFF Result increased from 34.1 ± 2.5 Hz to 36.5 ± 2.9 Hz after LOLA treatment with the adequate calories and protein intake including BCAAs substitution, which was statistically significant (p 0.001) compared to before treatment. The prealbumin level also increased significantly compared before treatment, i.e. from 5.4 ± 2.1 mg/dL to 6.4 ± 2.6 mg/dL, p = 0.008. Conclusion: HE patients with malnutrition could be given adequate calorie and protein with BCAAs substitution to improve their nutritional  status,  and  LOLA  granules for the improvement of HE. Keywords: minimal hepatic encephalopathy, malnutrition, CFF, LOLA, prealbumin, BCAAs
Efficacy of Combination Sofosbuvir, Pegylated-Interferon, and Ribavirin for Treatment of Hepatitis C Virus Genotype 1 Infection in Indonesia Andri Sanityoso Sulaiman; Rino Alvani Gani; Irsan Hasan; Cosmas Rinaldi A Lesmana; Juferdy Kurniawan; Chyntia Olivia Maurine Jasirwan; Kemal Fariz Kalista; Muhammad Yusuf Hanif
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 19, No 2 (2018): VOLUME 19, NUMBER 2, August 2018
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (475.176 KB) | DOI: 10.24871/192201874-78

Abstract

Background: The presence of direct-acting antiviral (DAA) has improved the treatment of HCV infection and making it more preferable than Pegylated-interferon (PegIFN) and Ribavirin (RBV) based treatment. However, treatment with all DAA combination regimen is limited and expensive in low health care affordability country including Indonesia. The appearance of generic sofosbuvir (SOF) facilitate the utilization of SOF plus PegINF with or withour RBV combination. Therefore, in this study we assessed the efficacy of SOF+RBV and SOF+RBV+PegINF combination for treatment of chronic hepatitis C infections patient with genotype 1 in Indonesia.Method: We performed retrospective study comprising 128 patients in Cipto Mangunkusumo Hospital with chronic hepatitis C, genotype 1, infection. 36 patients was treated with PegINF+SOF+RBV and 92 patients was treated with SOF+RBV with the duration of therapy was 12 and 24 weeks in both arms. The primary endpoint was sustained virologic response after treatment completion (SVR12).Results: In the end of treatment, 99.2% patients achieved undetected HCV RNA in 12 weeks and 24 weeks duration of therapy (100% in PegINF+SOF+RBV group and 98.9% in SOF+RBV group). The SVR12 of PegINF+SOF+RBV reach 100% meanwhile The SVR12 of SOF+RBV reach 88%.  No different in SVR12 between cirrhotic and non-cirrhotic patient in PegINF+SOF+RBV group while in SOF+RBV group, the SVR12 was lower in cirrhotic patients (82.9%) compared to non-cirrhotic patients (92.2%). In multivariate analysis, HIV co-infection is associated with lower SVR12 in SOF+RBV group.Conclusion: 12 weeks and 24 weeks of PegINF+SOF+RBV and SOF+RBV is effective in the treatment of genotype 1 chronic hepatitis C infection.
Co-Authors -, Gunawan - -, Gunawan - Abdul Aziz Rani Abdul Aziz Rani Abdul Rahman M Aditama, Humala Prika Agus Sudiro Waspodo Agus Waspodo Agustinus, Taolin Alessa Fahira Ali Sulaiman Ali Sulaiman Alvin Nursalim Alvin Nursalim Amanda Trixie Hardigaloeh Anandhara Indriani Khumaedi Anandhara Indriani Khumaedi, Anandhara Indriani ANDI UTAMA Andi Utama Andri Sanityoso Andri Sanityoso Andri Sanityoso Sulaeman Andri Sanityoso Sulaiman Aprilicia, Gita Ari Fahrial Syam Arnold Hasahatan Harahap Asep Saepul Rohmat Asep Saepul Rohmat, Asep Saepul Aulia Rizka, Aulia Azzaki Abubakar Azzaki Abubakar, Azzaki Baiq Kirana DN Mandasari Bambang Sutopo C Rinaldi A Lesmana C. Martin Rumende C. Martin Rumende, C. Martin Chyntia Olivia M. Jasirwan Chyntia Olivia Maurine Jasirwan, Chyntia Olivia Maurine Cleopas Martin Rumende Dadang Makmun Danang Agung Yunaidi Deskian Kostermans Deskian Kostermans, Deskian Diah Iskandriati E Mudjadid E. Mudjaddid A. Siswanto Deddy N.W.Achadiono Hamzah Shatri Edi Mulyana Edi Mulyana, Edi Edy Rizal Wahyudi Ening Krisnuhoni Eric Daniel Tenda Erni Erfan, Erni Esthika Dewiasty, Esthika Evy Yunihastuti Felix F Widjaja, Felix F FX Pridady Gita Aprilicia Gita Aprilicia Griscalia Christine Griskalia Christine Gunawan - - Guntur Darmawan H. M.S. Noer Hamzah Shatri Hamzah Shatri Hanif, Muhammad Yusuf Hardigaloeh, Amanda Trixie Hendra Koncoro Hilman Zulkifli Amin Idrus Alwi Idrus Alwi Idrus Alwi Ignatius Bima Prasetya, Ignatius Bima Iman Firmansyah Iman Firmansyah Imelda Maria Loho Imelda Maria Loho, Imelda Maria Indra Marki Indra Marki Jasirwan, Chyntia Olivia M Jeffry Beta Tenggara Juferdy Kurniawan Karmel Tambunan Kartika, Ronald Winardi Kemal F Calista Kemal Fariz Kalista Kemal Fariz Kalista Kemal Fariz Kalista Kemal Fariz Kalista, Kemal Fariz L A Lesmana L. A. Lesmana Laniyati Hamijoyo, Laniyati Laurentius A Lesmana Laurentius A Lesmana, Laurentius A Laurentius Lesmana Laurentius Lesmana Leonard Nainggolan Liana W. Susanto Lianda Siregar Lies Luthariana Lies Luthariana Lutfie Lutfie, Lutfie Marcellus Simadibrata Marcellus Simadibrata Marcellus Simadibrata Marcellus Simadibrata Marcellus Simadibrata Marcellus Simadibrata Martha Iskandar Maryati Surya Maulana Suryamin, Maulana Mondrowinduro, Prionggo Muhammad Sjaifoellah Noer Muhammad Yamin Lubis Muhammad Yamin Lubis, Muhammad Yamin Muhammad Yusuf Hanif Murdani Abdullah Murdani Abdullah Murdani Abdullah Murdani Abdullah Nababan, Saut Horas H. Nafrialdi Nafrialdi Nurul Akbar Nurul Akbar Paramita Khairan, Paramita Paulus Kusnanto Prionggo Mondrowinduro Pudji Rahardjo Pudji Rahardjo Raymond R. Tjandrawinata Rino A Gani Rino A Gani Rino A. Gani Rino Alvani Gani Rino Alvani Gani Rino Alvani Gani Rino Alvani Gani Rino Alvani Gani Rino Alvani Gani Rino Alvani Gani Rino Alvani Gani Rino Alvani Gani Rino Alvani Gani Rino Alvani Gani Ruswhandi - Ruswhandi -, Ruswhandi Salius Silih Sartika, Katarina Dewi Saut HH Nababan Saut Horas H. Nababan Saut Horas Hatoguan Nababan Saut Horas Hatoguan Nababan Saut Horas Hatoguan Nababan Seruni Tyas Khairunissa Silmi Mariya Siti Setiati Sjaifoellah Noer Soemarno Soemarno Soemarno Soemarno Suhendro Suhendro Suhendro Suwarto Suhendro Suwarto, Suhendro Sulaeman, Andri Sanityoso Suradji, Eka Widrian Susan Tai Suzanna Ndraha Syahrizal Syarif Taolin Agustinus Teguh H. Karjadi Teguh H. Karjadi, Teguh H. Telly Kamelia Tendean, Marcel Teng, Wei Teressa, Maria THARIQAH SALAMAH, THARIQAH Unggul Budihusodo Wiguna, Candra Wijaya, Indra Wismandari Wisnu Yaldiera Utami Yaldiera Utami, Yaldiera Yong, Bernard Jonathan Christian Zulkifly, Steven