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All Journal The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy

Randy Adiwinata

Faculty of Medicine, Atmajaya Catholic University, Jakarta

Author-ID : 5436256

Medicine & Pharmacology

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Articles

Polycystic Liver Disease: A Case Report Randy Adiwinata; Natalin Allorerung; Jonathan Arifputra; Andrea Livina; Pearla Lasut; Bradley Jimmy Waleleng; Fandy Gosal; Luciana Rotty; Jeanne Winarta; Andrew Waleleng; Michael Tendean
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 22, No 2 (2021): VOLUME 22, NUMBER 2, August 2021
Publisher : The Indonesian Society for Digestive Endoscopy

Polycystic liver disease is characterized by multiple cystic lesions on the liver. Liver cysts are typically incidental findings, with occasional complications including cyst hemorrhage, infection and rupture. Polycystic liver disease may be part of autosomal dominant polycystic liver disease (ADPLD). Autosomal dominant polycystic liver disease is considered rare autosomal dominant disease, with prevalence of 1/100,000-1,000,000. Without family history of polycystic liver disease, ADPLD is defined as the presence of more than 20 liver cysts with no renal cysts, however up to third of ADPLD may have small number of renal cysts without kidney function impairment. This case of a 73-year-old woman with symptomatic polycystic liver disease, and we performed cyst fenestration-deroofing via laparoscopic.

Bowel Obstruction and Perforation as Emergency Presenting Sign of Colorectal Cancer with Peritoneal Carcinomatosis: A Case Report and Review Randy Adiwinata; Linda Rotty; Michael Tendean; Bradley Jimmy Waleleng; Fandy Gosal; Luciana Rotty; Jeanne Winarta; Andrew Waleleng
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 21, No 3 (2020): VOLUME 21, NUMBER 3, December 2020
Publisher : The Indonesian Society for Digestive Endoscopy

Colorectal cancer patient may present with variable clinical presentation. In few cases, colorectal cancer may present as emergency such as uncontrollable gastrointestinal bleeding, large bowel obstruction and in rarer fashion is bowel perforation. Worse prognosis is linked with emergency presenting colorectal cancer. Peritoneal carcinomatosis may occur in 10-35% of colorectal cancer patients and may develop bowel obstruction along with the primary colorectal cancer. Here, we report a-62-year-old man presented with large bowel obstruction leading to perforation without known history of colorectal cancer before. On emergency laparotomy, we found colorectal cancer and peritoneal carcinomatosis as the underlying cause. Prompt diagnosis and urgent management is warranted to improve the prognosis.

The Role of Vitamin D in Inflammatory Bowel Disease Pathogenesis and Management Randy Adiwinata; Marcellus Simadibrata
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 18, No 1 (2017): VOLUME 18, NUMBER 1, April 2017
Publisher : The Indonesian Society for Digestive Endoscopy

Vitamin D is widely recognized in maintaining bone metabolism and health. However, recent studies indicated that vitamin D also play important role in regulating immune system. Patients with inflammatory bowel disease (IBD) is commonly found to be vitamin D deficiency; whether it served as risk factor of IBD or as the consequence of disease activity are still debatable. Growing evidences showed that supplementation of vitamin D for IBD patients to achieve normal or optimal serum level may suppress the inflammatory process, reduce disease severity, maintaining remission status, and improving quality of life.

The Association between Interleukin-6 and Mean Platelet Volume Levels in Central Obesity with or without Non-Alcoholic Fatty Liver Disease Linda Rotty; Nelly Tendean; Nancy Lestari; Randy Adiwinata
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 21, No 3 (2020): VOLUME 21, NUMBER 3, December 2020
Publisher : The Indonesian Society for Digestive Endoscopy

Background: Obesity had become a global problem today. Obesity is a significant risk factor of cardiovascular and other metabolic diseases such as non-alcoholic fatty liver disease (NAFLD). It remains unclear if the increased mean platelet volume (MPV) at the steatosis state is practicable as early detection of the occurrence of fatty liver in individuals with central obesity. This study aims to determine the association of interleukin-6 (IL-6) and MPV levels in central obesity with or without NAFLD.Method: This study was descriptive-analytic with a cross-sectional approach conducted in Prof. dr. R. D. Kandou Manado general hospital from May to July 2018. Consecutive sampling was performed based on inclusion criteria, then IL-6, MPV, and abdominal ultrasound examinations were performed.Results: This study included 40 samples of men with central obesity, 28 people (70%) among them were diagnosed with NAFLD. The Fisher exact test showed an association between NAFLD and an increase in IL-6 (p = 0.039), also between MPV and NAFLD (p=0.015). Pearson correlation test showed there was no significant correlation between IL-6 and MPV in the NAFLD sample group (p = 0.084; r -0.332) and in the non-NAFLD sample group (p = 0.564; r -0.186).Conclusion: Elevated MPV and IL-6 values may be used as marker for NAFLD presence among central obesity patients.

Co-Authors Andrea Livina Andrew Waleleng Andrew Waleleng Bradley Jimmy Waleleng Bradley Jimmy Waleleng Fandy Gosal Fandy Gosal Jeanne Winarta Jeanne Winarta Jonathan Arifputra Linda Rotty Linda Rotty Luciana Rotty Luciana Rotty Marcellus Simadibrata Michael Tendean Michael Tendean Nancy Lestari Natalin Allorerung Nelly Tendean Pearla Lasut

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