The Role of Vitamin D in Inflammatory Bowel Disease Pathogenesis and Management

Randy Adiwinata (Faculty of Medicine, Atmajaya Catholic University, Jakarta)
Marcellus Simadibrata (Division of Gastroenterology, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia/Dr. Cipto Mangunkusumo General National Hospital, Jakarta)

The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy
Vol 18, No 1 (2017): VOLUME 18, NUMBER 1, April 2017

Vitamin D is widely recognized in maintaining bone metabolism and health. However, recent studies indicated that vitamin D also play important role in regulating immune system. Patients with inflammatory bowel disease (IBD) is commonly found to be vitamin D deficiency; whether it served as risk factor of IBD or as the consequence of disease activity are still debatable. Growing evidences showed that supplementation of vitamin D for IBD patients to achieve normal or optimal serum level may suppress the inflammatory process, reduce disease severity, maintaining remission status, and improving quality of life.