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All Journal Bioscientia Medicina : Journal of Biomedicine and Translational Research Bioscientia Medicina : Journal of Biomedicine and Translational Research
Didik Hariyanto
Department of Pediatrics, Faculty of Medicine, Universitas Andalas, Padang, Indonesia
Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Neuroscience

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Correlation of Neutrophil to Lymphocyte Ratio (NLR) Values to Ejection Fraction, Fraction Shortening, and E/A Ratio in Children with Rheumatic Heart Disease (RHD) at Dr. M. Djamil General Hospital, Padang, Indonesia Farid I Hussein; Didik Hariyanto; Amirah Zatil Izzah
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 6 No. 16 (2022): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v6i16.698

Abstract

Background: Monitoring the performance of the cardiac function is a must in monitoring patients with rheumatic heart disease (RHD). Echocardiography is the main diagnostic tool that plays a role in monitoring heart function, but the existence of this tool is only in tertiary health services and generally requires special expertise. This study aims to determine the correlation between the neutrophil to lymphocyte ratio (NLR) and markers of cardiac function performance on echocardiography, namely ejection fraction, fraction shortening, and E/A ratio in children with rheumatic heart disease at Dr. M. Djamil General Hospital, Padang, Indonesia. Methods: This was an analytical observational study with a cross-sectional approach. A total of 34 subjects were included in this study. Data analysis using SPSS was univariate and bivariate, with p<0.05. Results: There was a correlation between the NLR value and the echocardiographic ejection fraction (EF) parameter (p>0.05) with a very weak correlation strength, while the correlation between the NLR value and the FS echocardiography parameter (p<0.05), the direction of the correlation formed is positive with a strong correlation weak (r=0.388). As for the correlation of NLR values with echocardiographic parameters E/A (p<0.05), the direction of the correlation formed was positive with a weak correlation strength (r=0.353). Conclusion: There is a weak correlation between NLR values with FS and E/A echocardiographic parameters and no correlation between NLR and EF echocardiographic parameters in rheumatic heart disease patients at Dr. M. Djamil General Hospital, Padang, Indonesia.
Correlation of Neutrophil to Lymphocyte Ratio (NLR) Values to Ejection Fraction, Fraction Shortening, and E/A Ratio in Children with Rheumatic Heart Disease (RHD) at Dr. M. Djamil General Hospital, Padang, Indonesia Farid I Hussein; Didik Hariyanto; Amirah Zatil Izzah
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 6 No. 16 (2022): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v6i16.698

Abstract

Background: Monitoring the performance of the cardiac function is a must in monitoring patients with rheumatic heart disease (RHD). Echocardiography is the main diagnostic tool that plays a role in monitoring heart function, but the existence of this tool is only in tertiary health services and generally requires special expertise. This study aims to determine the correlation between the neutrophil to lymphocyte ratio (NLR) and markers of cardiac function performance on echocardiography, namely ejection fraction, fraction shortening, and E/A ratio in children with rheumatic heart disease at Dr. M. Djamil General Hospital, Padang, Indonesia. Methods: This was an analytical observational study with a cross-sectional approach. A total of 34 subjects were included in this study. Data analysis using SPSS was univariate and bivariate, with p<0.05. Results: There was a correlation between the NLR value and the echocardiographic ejection fraction (EF) parameter (p>0.05) with a very weak correlation strength, while the correlation between the NLR value and the FS echocardiography parameter (p<0.05), the direction of the correlation formed is positive with a strong correlation weak (r=0.388). As for the correlation of NLR values with echocardiographic parameters E/A (p<0.05), the direction of the correlation formed was positive with a weak correlation strength (r=0.353). Conclusion: There is a weak correlation between NLR values with FS and E/A echocardiographic parameters and no correlation between NLR and EF echocardiographic parameters in rheumatic heart disease patients at Dr. M. Djamil General Hospital, Padang, Indonesia.
Overview of Risk Factors for Toddlers with Congenital Heart Disease Suffering from Pneumonia at Dr. M. Djamil General Hospital, Padang, Indonesia Ricco Azali; Didik Hariyanto; Finny Fitry Yani
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 6 No. 17 (2023): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v6i17.717

Abstract

Background: Congenital heart disease (CHD) includes structural and non-structural abnormalities that arise from birth. Disorders of the circulatory system can also affect the respiratory system, causing symptoms and disturbances that similar to primary respiratory disease. This study aimed to describe the risk factors for toddlers with congenital heart disease who suffer from pneumonia at Dr. M. Djamil General Hospital, Padang, Indonesia. Methods: Descriptive observational study using secondary data. A total of 58 research subjects participated in the study. The research subjects met the inclusion criteria in the form of patients who had been diagnosed with congenital heart disease, aged 29 days – 60 months, and were treated at Dr. M. Djamil General Hospital, Padang, Indonesia. Data analysis was performed using SPSS software univariately. Results: The majority of patients with various age levels have a cured outcome. The majority of subjects with medium and high parental education had a greater recovery percentage than subjects with low parental education. Subjects with medium and high socioeconomic status had a greater percentage of recovery outcomes than subjects with low socioeconomic status. The majority of subjects with normal nutritional status and normal birth weight had a higher percentage of recovered outcomes than those who died. The history of DPT immunization and the type of congenital heart disease did not show a large percentage difference between patients who recovered and died. History of measles immunization and leukocytosis showed a greater percentage of patients with cured outcomes than death outcomes. Conclusion: CHD patients with pneumonia are under 1 year old, male, come from families with low-medium socioeconomic status, low-medium educational level, and malnutrition status have worse patient outcomes.
Overview of Risk Factors for Toddlers with Congenital Heart Disease Suffering from Pneumonia at Dr. M. Djamil General Hospital, Padang, Indonesia Ricco Azali; Didik Hariyanto; Finny Fitry Yani
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 6 No. 17 (2023): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v6i17.717

Abstract

Background: Congenital heart disease (CHD) includes structural and non-structural abnormalities that arise from birth. Disorders of the circulatory system can also affect the respiratory system, causing symptoms and disturbances that similar to primary respiratory disease. This study aimed to describe the risk factors for toddlers with congenital heart disease who suffer from pneumonia at Dr. M. Djamil General Hospital, Padang, Indonesia. Methods: Descriptive observational study using secondary data. A total of 58 research subjects participated in the study. The research subjects met the inclusion criteria in the form of patients who had been diagnosed with congenital heart disease, aged 29 days – 60 months, and were treated at Dr. M. Djamil General Hospital, Padang, Indonesia. Data analysis was performed using SPSS software univariately. Results: The majority of patients with various age levels have a cured outcome. The majority of subjects with medium and high parental education had a greater recovery percentage than subjects with low parental education. Subjects with medium and high socioeconomic status had a greater percentage of recovery outcomes than subjects with low socioeconomic status. The majority of subjects with normal nutritional status and normal birth weight had a higher percentage of recovered outcomes than those who died. The history of DPT immunization and the type of congenital heart disease did not show a large percentage difference between patients who recovered and died. History of measles immunization and leukocytosis showed a greater percentage of patients with cured outcomes than death outcomes. Conclusion: CHD patients with pneumonia are under 1 year old, male, come from families with low-medium socioeconomic status, low-medium educational level, and malnutrition status have worse patient outcomes.
Co-Authors Amirah Zatil Izzah Farid I Hussein Finny Fitry Yani Ricco Azali