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All Journal Sari Pediatri Paediatrica Indonesiana Majalah Kedokteran Andalas Bioscientia Medicina : Journal of Biomedicine and Translational Research Health and Medical Journal Human Care Journal Bioscientia Medicina : Journal of Biomedicine and Translational Research
Didik Hariyanto
Universitas Andalas
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

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Profil Penyakit Jantung Bawaan di Instalasi Rawat Inap Anak RSUP Dr.M.Djamil Padang Januari 2008 – Februari 2011 Didik Hariyanto
Sari Pediatri Vol 14, No 3 (2012)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (76.059 KB) | DOI: 10.14238/sp14.3.2012.152-7

Abstract

Latar belakang. Insidens penyakit jantung bawaan (PJB) di dunia memiliki angka yang konstan, sekitar 8-10 dari 1000 kelahiran hidup. Malformasi yang terdapat tidak terdeteksi dengan mudah pada periode neonatal, beberapa diantaranya terjadi modifikasi dan menghilang selama masa bayi dan anak. Kasus PJB terbanyak diketahui saat datang dengan keluhan non kardiakTujuan. Mengetahui karakteristik pasien penyakit jantung bawaan yang dirawat di instalasi rawat inap RSUP dr. M.Djamil Padang periode Januari 2008 sampai Februari 2011, meliputi jenis penyakit jantung bawaan, umur, jenis kelamin, status gizi, dan penyakit penyerta.Metode. Penelitian deskriptif berdasarkan data rekam medis pasien yang dirawat selama periode Januari 2008 sampai dengan Februari 2011. Diagnosis ditegakkan berdasarkan, pemeriksaan ekokardiografi.Hasil. Dari 98 pasien yang dirawat, rata-rata berumur 1 bulan sampai 1 tahun, perempuan 51% dan lakilaki 49%. Kasus terbanyak VSD dan ASD, masing masing sebesar 35(35%) kasus. Status gizi terbanyak adalah gizi kurang dan 6 pasien datang dengan keadaah sudah mengalami gagal tumbuh. Bronkopneumonia (32,6%) pasien merupakan penyakit penyerta terbanyak yang membawa anak datang berobat.Tiga orang (3%) dirawat dengan gejala gagal jantung, 3 dengan kelainan hemato-onkologi, dan 41 tanpa disertai penyakit penyerta.Kesimpulan.Pasien penyakit jantung bawaan yang dirawat pada umumnya datang pada umur 1 bulan sampai 1 tahun dengan status gizi kurang. VSD dan ASD merupakan PJB terbanyak yang ditemui. Bronkopneumonia adalah penyakti penyerta dominan.
Bacterial pneumonia score to identify bacterial pneumonia Ied Imilda; Finny Fitry Yani; Didik Hariyanto; Darfioes Basir
Paediatrica Indonesiana Vol 55 No 2 (2015): March 2015
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (98.784 KB) | DOI: 10.14238/pi55.2.2015.79-82

Abstract

Background Pneumonia is caused by either bacterial or viraletiologies, with similar symptoms in children. The bacterialpneumonia score (BPS) is a clinical assessment comprised ofseveral investigations: age, assessment of axillary temperature,absolute neutrophil count, band neutrophil percentage, andinterpretation of radiological examination. The score will use todifferentiate the etiology of pneumonia.Objective To determine the sensitivity, specificity, positivepredictive value, and negative predictive value of BPS inidentifying bacterial pneumonia in children.Methods This diagnostic study was performed at Dr. M. DjamilHospital, Padang, West Sumatera where subjects were selected byconsecutive sampling. Fifty-seven patients were diagnosed withpneumonia. Three patients suffered from ventricular septal defects,8 patients refused to provide blood specimens and 3 patients’chest X-rays could not be interpreted, hence, 43 subjects wereincluded in the study. Chest X-rays were interpreted by a pediatricpulmonology consultant. Leukocyte and differential counts wereperformed by a clinical pathology consultant. Subjects’ BPS scoreswere compared to multiplex PCR examinations of blood specimens,as the gold standard.Result Of 43 subjects, 27 (62.79%) were male. Subjects’ mean age was 29.3 (SD 21.5) months. Twenty (46.51%) subjects had good nutritional status, 4 (9.31%) subjects had axillary temperature ≥39°C, and 22 (51.16%) subjects had absolute neutrophil counts ≥8.000/mm3. Bacterial pneumonia score (BPS) had 69% sensitivity, 60% specificity, 42% positive predictive value, and 81% negative predictive value.Conclusion In this study, BPS has low sensitivity and specificityfor identifying bacterial pneumonia.
Dilated Cardiomyopathy Concomitant with Acute Rheumatic Fever and Sporadic Hereditary Spherocytosis Fitrisia Amelin; Didik Hariyanto; Amizah Zatil Izzah
Health and Medical Journal Vol 2, No 2 (2020): HEME July 2020
Publisher : Universitas Baiturrahmah

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (395.324 KB) | DOI: 10.33854/heme.v2i2.460

Abstract

Background: Dilated cardiomyopathy (DCM) is a heart muscle disorder defined by the presence of a dilated and poorly functioning left ventricle in the absence of abnormal loading conditions (hypertension, valve disease) or ischaemic heart disease sufficient to cause global systolic impairment. Case report: A 5 years old and 6 months old girl with unremarkable cardiac history hospitalized for congestive heart failure due to dilated cardiomyopathy concomitant with acute rheumatic fever and sporadic hereditary spherocytosis. Acute rheumatic fever diagnosed based on the presentation of carditis, fever, high erythrocyte sedimentation rate, C-Reactive Protein (+), and antistreptolysin titer O (+). DCM was diagnosed after echocardiography. Sporadic hereditary spherocytosis was diagnosed based on anamnesis of pale and jaundice, splenomegaly on physical examination, hemolytic anemia, reticulocytosis, spherosit (+). Both parents reveals normal hematologic finding and the osmotic resistance test showed increasing of osmotic fragility. Conclusion: Prognosis of this patient remains worse because of inadequate left ventricle-right ventricle (LV-RV) function and highly increasing The N-terminal prohormone of brain natriuretic peptide (NT-proBNP) level.
DEMAM REMATIK AKUT PADA ANAK Melisha Lisman Gaya; Didik Hariyanto
HUMAN CARE JOURNAL Vol 6, No 2 (2021): Human Care Journal
Publisher : Universitas Fort De Kock

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32883/hcj.v6i2.1219

Abstract

Latar Belakang: Demam rematik akut (DRA) merupakan penyakit autoimun yang terjadi pasca infeksi Streptococcus β hemoliticus grup A yang dapat mengenai berbagai jaringan. Tatalaksana yang tidak adekuat dapat meningkatkan risiko infeksi Streptococcus β hemoliticus grup A menjadi DRA sebesar 25-75%. Pencegahan dini dan pengobatan yang tepat dapat mengehentikan atau memperlambat progresifitas penyakit.Tujuan: Tujuan penulisan kasus ini adalah untuk memaparkan mengenai manifestasi klinis dan manajemen demam rematik akut. Kasus: Seorang anak perempuan usia 14 tahun 3 bulan memenuhi kriteria Jones revisi tahun 2015 untuk penegakan diagnosis DRA dengan memiliki 2 kriteria mayor berupa nyeri sendi berpindah dan karditis klinis (kardiomegali ringan dan MR (mitral regurgitation) mild ec prolaps AML (anterior mitral leaflet), serta 2 kriteria minor berupa riwayat demam dan LED 102 mm/jam. Pemeriksaan laboratorium darah menunjukkan adanya peningkatan titer ASTO yang merupakan bukti adanya riwayat infeksi Streptococcus. Pasien ditatalaksana sebagai demam rematik akut dengan tirah baring selama 4-6 minggu, injeksi benzatin penicillin intramuscular (IM) dosis 1.200.000 IU, prednisone 2 mg/kg/hari selama 2 minggu, kemudian tapering off selama 2-4 minggu asetosal 75 mg/kg/hari pada minggu ke-3 hingga 4 kemudian tapering off selama 2-4 minggu. Pasien juga mendapat profilaksis sekunder dengan injeksi benzatin penicillin 1.200.000 IU IM setiap 28 hari.
The Relationship between Accurate Use of Antibiotics and Clinical Improvement of Sepsis in Neonates Using the Gyssens Method in the Perinatology Ward of Dr. M. Djamil General Hospital, Padang Indonesia Freidlander Pangestu; Rinang Mariko; Didik Hariyanto
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 6 No. 12 (2022): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v6i12.621

Abstract

Background: Neonatal sepsis is a major cause of neonatal morbidity and mortality in developing countries. Inappropriate use of antibiotics causes an increase in antibiotic resistance, so the Gyssens method is needed, which is a qualitative method and is used to evaluate the use of antibiotics. This study aims to determine the relationship between the accuracy of the use of antibiotics using the Gyssens method on the clinical improvement of neonates in the Perinatology Ward of Dr. M. Djamil General Hospital Padang, Indonesia. Methods: This study used a cross-sectional conducted from January 2020 to December 2020. The study subjects were 67 neonates diagnosed with sepsis in the perinatology ward of Dr. M. Djamil General Hospital, Padang Indonesia. Data analysis was performed with SPSS for univariate and bivariate analysis. Results: Most neonatal sepsis occurs in male infants who have low birth weight. Most cultures do not grow. There was an improvement in clinical and hematological parameters to the administration of first-line, second-line, and culture-appropriate antibiotics according to the Gyssens method, but statistically not significant (p-value > 0.05). The rational use of antibiotics was 89.6%. Conclusion: There is a relationship between the accuracy of antibiotic use on clinical improvement and blood parameters of neonatal sepsis patients in the Perinatology ward of Dr. M. Djamil General Hospital based on the Gyssens method, but it is not statistically significant. The use of antibiotics based on the Gyssens method at Dr. M. Djamil General Hospital is quite good.
Correlation of Neutrophil to Lymphocyte Ratio (NLR) Values to Ejection Fraction, Fraction Shortening, and E/A Ratio in Children with Rheumatic Heart Disease (RHD) at Dr. M. Djamil General Hospital, Padang, Indonesia Farid I Hussein; Didik Hariyanto; Amirah Zatil Izzah
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 6 No. 16 (2022): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v6i16.698

Abstract

Background: Monitoring the performance of the cardiac function is a must in monitoring patients with rheumatic heart disease (RHD). Echocardiography is the main diagnostic tool that plays a role in monitoring heart function, but the existence of this tool is only in tertiary health services and generally requires special expertise. This study aims to determine the correlation between the neutrophil to lymphocyte ratio (NLR) and markers of cardiac function performance on echocardiography, namely ejection fraction, fraction shortening, and E/A ratio in children with rheumatic heart disease at Dr. M. Djamil General Hospital, Padang, Indonesia. Methods: This was an analytical observational study with a cross-sectional approach. A total of 34 subjects were included in this study. Data analysis using SPSS was univariate and bivariate, with p<0.05. Results: There was a correlation between the NLR value and the echocardiographic ejection fraction (EF) parameter (p>0.05) with a very weak correlation strength, while the correlation between the NLR value and the FS echocardiography parameter (p<0.05), the direction of the correlation formed is positive with a strong correlation weak (r=0.388). As for the correlation of NLR values with echocardiographic parameters E/A (p<0.05), the direction of the correlation formed was positive with a weak correlation strength (r=0.353). Conclusion: There is a weak correlation between NLR values with FS and E/A echocardiographic parameters and no correlation between NLR and EF echocardiographic parameters in rheumatic heart disease patients at Dr. M. Djamil General Hospital, Padang, Indonesia.
The Relationship between Accurate Use of Antibiotics and Clinical Improvement of Sepsis in Neonates Using the Gyssens Method in the Perinatology Ward of Dr. M. Djamil General Hospital, Padang Indonesia Freidlander Pangestu; Rinang Mariko; Didik Hariyanto
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 6 No. 12 (2022): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v6i12.621

Abstract

Background: Neonatal sepsis is a major cause of neonatal morbidity and mortality in developing countries. Inappropriate use of antibiotics causes an increase in antibiotic resistance, so the Gyssens method is needed, which is a qualitative method and is used to evaluate the use of antibiotics. This study aims to determine the relationship between the accuracy of the use of antibiotics using the Gyssens method on the clinical improvement of neonates in the Perinatology Ward of Dr. M. Djamil General Hospital Padang, Indonesia. Methods: This study used a cross-sectional conducted from January 2020 to December 2020. The study subjects were 67 neonates diagnosed with sepsis in the perinatology ward of Dr. M. Djamil General Hospital, Padang Indonesia. Data analysis was performed with SPSS for univariate and bivariate analysis. Results: Most neonatal sepsis occurs in male infants who have low birth weight. Most cultures do not grow. There was an improvement in clinical and hematological parameters to the administration of first-line, second-line, and culture-appropriate antibiotics according to the Gyssens method, but statistically not significant (p-value > 0.05). The rational use of antibiotics was 89.6%. Conclusion: There is a relationship between the accuracy of antibiotic use on clinical improvement and blood parameters of neonatal sepsis patients in the Perinatology ward of Dr. M. Djamil General Hospital based on the Gyssens method, but it is not statistically significant. The use of antibiotics based on the Gyssens method at Dr. M. Djamil General Hospital is quite good.
Correlation of Neutrophil to Lymphocyte Ratio (NLR) Values to Ejection Fraction, Fraction Shortening, and E/A Ratio in Children with Rheumatic Heart Disease (RHD) at Dr. M. Djamil General Hospital, Padang, Indonesia Farid I Hussein; Didik Hariyanto; Amirah Zatil Izzah
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 6 No. 16 (2022): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v6i16.698

Abstract

Background: Monitoring the performance of the cardiac function is a must in monitoring patients with rheumatic heart disease (RHD). Echocardiography is the main diagnostic tool that plays a role in monitoring heart function, but the existence of this tool is only in tertiary health services and generally requires special expertise. This study aims to determine the correlation between the neutrophil to lymphocyte ratio (NLR) and markers of cardiac function performance on echocardiography, namely ejection fraction, fraction shortening, and E/A ratio in children with rheumatic heart disease at Dr. M. Djamil General Hospital, Padang, Indonesia. Methods: This was an analytical observational study with a cross-sectional approach. A total of 34 subjects were included in this study. Data analysis using SPSS was univariate and bivariate, with p<0.05. Results: There was a correlation between the NLR value and the echocardiographic ejection fraction (EF) parameter (p>0.05) with a very weak correlation strength, while the correlation between the NLR value and the FS echocardiography parameter (p<0.05), the direction of the correlation formed is positive with a strong correlation weak (r=0.388). As for the correlation of NLR values with echocardiographic parameters E/A (p<0.05), the direction of the correlation formed was positive with a weak correlation strength (r=0.353). Conclusion: There is a weak correlation between NLR values with FS and E/A echocardiographic parameters and no correlation between NLR and EF echocardiographic parameters in rheumatic heart disease patients at Dr. M. Djamil General Hospital, Padang, Indonesia.
Overview of Risk Factors for Toddlers with Congenital Heart Disease Suffering from Pneumonia at Dr. M. Djamil General Hospital, Padang, Indonesia Ricco Azali; Didik Hariyanto; Finny Fitry Yani
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 6 No. 17 (2023): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v6i17.717

Abstract

Background: Congenital heart disease (CHD) includes structural and non-structural abnormalities that arise from birth. Disorders of the circulatory system can also affect the respiratory system, causing symptoms and disturbances that similar to primary respiratory disease. This study aimed to describe the risk factors for toddlers with congenital heart disease who suffer from pneumonia at Dr. M. Djamil General Hospital, Padang, Indonesia. Methods: Descriptive observational study using secondary data. A total of 58 research subjects participated in the study. The research subjects met the inclusion criteria in the form of patients who had been diagnosed with congenital heart disease, aged 29 days – 60 months, and were treated at Dr. M. Djamil General Hospital, Padang, Indonesia. Data analysis was performed using SPSS software univariately. Results: The majority of patients with various age levels have a cured outcome. The majority of subjects with medium and high parental education had a greater recovery percentage than subjects with low parental education. Subjects with medium and high socioeconomic status had a greater percentage of recovery outcomes than subjects with low socioeconomic status. The majority of subjects with normal nutritional status and normal birth weight had a higher percentage of recovered outcomes than those who died. The history of DPT immunization and the type of congenital heart disease did not show a large percentage difference between patients who recovered and died. History of measles immunization and leukocytosis showed a greater percentage of patients with cured outcomes than death outcomes. Conclusion: CHD patients with pneumonia are under 1 year old, male, come from families with low-medium socioeconomic status, low-medium educational level, and malnutrition status have worse patient outcomes.
Overview of Risk Factors for Toddlers with Congenital Heart Disease Suffering from Pneumonia at Dr. M. Djamil General Hospital, Padang, Indonesia Ricco Azali; Didik Hariyanto; Finny Fitry Yani
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 6 No. 17 (2023): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v6i17.717

Abstract

Background: Congenital heart disease (CHD) includes structural and non-structural abnormalities that arise from birth. Disorders of the circulatory system can also affect the respiratory system, causing symptoms and disturbances that similar to primary respiratory disease. This study aimed to describe the risk factors for toddlers with congenital heart disease who suffer from pneumonia at Dr. M. Djamil General Hospital, Padang, Indonesia. Methods: Descriptive observational study using secondary data. A total of 58 research subjects participated in the study. The research subjects met the inclusion criteria in the form of patients who had been diagnosed with congenital heart disease, aged 29 days – 60 months, and were treated at Dr. M. Djamil General Hospital, Padang, Indonesia. Data analysis was performed using SPSS software univariately. Results: The majority of patients with various age levels have a cured outcome. The majority of subjects with medium and high parental education had a greater recovery percentage than subjects with low parental education. Subjects with medium and high socioeconomic status had a greater percentage of recovery outcomes than subjects with low socioeconomic status. The majority of subjects with normal nutritional status and normal birth weight had a higher percentage of recovered outcomes than those who died. The history of DPT immunization and the type of congenital heart disease did not show a large percentage difference between patients who recovered and died. History of measles immunization and leukocytosis showed a greater percentage of patients with cured outcomes than death outcomes. Conclusion: CHD patients with pneumonia are under 1 year old, male, come from families with low-medium socioeconomic status, low-medium educational level, and malnutrition status have worse patient outcomes.
Co-Authors Amelin, Fitrisia Amirah Zatil Izzah Amizah Zatil Izzah Aulia Rahman Darfioes Basir Farid I Hussein Finny Fitry Yani Freidlander Pangestu Ied Imilda Melisha Lisman Gaya Novialdi . Ricco Azali Rinang Mariko Rismawati Yaswir Syahri Gunawan