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All Journal Jurnal Ilmiah Farmasi Farmasyifa Jurnal Katalisator
Miftahur Rahmi
Universitas Perintis Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology

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EVALUASI INVITRO AKTIVITAS ANTIOKSIDAN DAN TABIR SURYA DARI EKSTRAK DAUN DAN AKAR TUMBUHAN Elephantopus mollis Kunth Verawati Verawati; Miftahur Rahmi; Intan Suci Mayasari
Jurnal Ilmiah Farmasi Farmasyifa Vol 5, No 2 (2022)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/jiff.v5i2.8361

Abstract

Solar radiation in Indonesia is quite abundant because geographically it is located at equatorial latitudes, so people are vulnerable to feel the bad effects of solar radiation. Chemical components with antioxidant properties can also act as sunscreens to prevent the negative effects of solar radiation. This study aimed to determine the antioxidant and sunscreen activity of the leaf and root extract of the Tutup Bumi (Elephantopus mollis Kunth) plant. The antioxidant activity test was examined by the DPPH radical scavenging method (2,2-diphenyl-1-picrylhydrazyl) while the sunscreen potency was determined by calculating the SPF value using the Mansur method spectrophotometrically. The results of the examination showed that the antioxidant activity was quite strong, namely the leaf extract with IC50 79.38 g/mL and root extract 78.38 g/mL. The SPF value of the leaf extract is better than that of the root extract, where at a concentration of 500 ppm, the leaf extract has an SPF of 7.661 in the Extra category while the root extract at the same concentration has an SPF value of 5.176 in the Medium category. Tutup Bumi leaf and root extracts have potential as antioxidants and sunscreens.
EFFECTIVENESS THE OINTMENT OF FOREST BETEL LEAVES EXTRACT (Piper aduncum L. ) AGAINST EXCISION WOUNDS Diza Sartika; Ria Afrianti; Rihadhatul Aisy; Miftahur Rahmi
JURNAL KATALISATOR Vol. 9 No. 1 (2024): Jurnal Katalisator Volume 9 No.1, April 2024
Publisher : LLDIKTI X Sumbar, Riau, Jambi, Kepri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62769/katalisator.v9i1.2821

Abstract

Excision wounds are included in open wounds and occupy the top three types of injuries experienced by the public. Forest betel (Piper aduncum L) is one of the plants that can be used in healing excision wounds because it contains several chemical ingredients such as flavonoids, steroids and saponins which can help speed up wound healing. This study aims to determine the effectiveness of ointment extracts of forest betel leaves (Piper aduncum L.) on the healing of excision wounds in male albino rats. Animals are divided into 5 groups there are control group (base used of vaselinflavum ointment), group of forest betel leaf extract concentration 5%, 10%, 15% and the comparison group (Ointment T®). Basting of preparation was done twice a day for 21 days. The parameters observed were the percentage of wound healing, epithelialization time and histopathology. The results showed on the average percentage of excision wound healing on the 7th, 14th and 21st days were control group ( 43.046% , 84.118%, 92.866% ), concentration 5% (45.49%, 87 608%, 94.704%), concentration of 10% (46.196%, 88.24%, 96.692%), concentration of 15% (46.572%, 91.058%, 97.886%) and the comparison group (46.572%, 90.01%, 97.372%). the control group (8 days), 5% concentration (7 days), 10% concentration (6.8 days), 15% concentration (6.4 days) and the comparison group (6.6 days).For the histopathological test, the results of epithelialization, collagen fiber, and fibroblast scores were. respectively the control group (2,2,1), 5% concentration (2,2,2), 10% concentration (2,2,2), 15% concentration (3,3,3) and the comparison group (3 ,3,3). The most effective group for excision wound healing was the 15% concentration group.
Co-Authors Intan Suci Mayasari Ria Afrianti Rihadhatul Aisy Sartika, Diza Verawati