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Construction of biology magazine based on the antidiabetic test of pasak bumi roots Michelle Terrence; Ruqiah Ganda Putri Panjaitan; Afandi Afandi
JPBIO (Jurnal Pendidikan Biologi) Vol 7, No 2 (2022): November 2022
Publisher : STKIP Persada Khatulistiwa Sintang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31932/jpbio.v7i2.1754

Abstract

The enrichment program is an additional effort or activity given to students who have achieved complete learning with the aim of increasing students' understanding and insight into the material being or has been studied. In carrying out the enrichment program, teachers can use enrichment materials as learning resources, one of which is a biology magazine. This study aims to develop a biology magazine as an enrichment material to increase students' understanding and insight into the hormone system sub-material. This type of research is an R&D research that uses an adaptation of the 4D Thiagarajan model, namely define, design, and development. The data sources for this research consisted of 36 students from Christian High School Immanuel Pontianak and SMA Santo Fransiskus Asisi Pontianak, 3 biology teachers from these schools, and 3 lecturers of Biology Education FKIP UNTAN. The results of the analysis of student needs indicate that it is necessary to develop a biology magazine in order to motivate students to increase their understanding and insight. The results of the feasibility test can be seen that biological magazines are suitable for use as material for enrichment of the hormone system sub-material, this is indicated by the Aiken's V value obtained 0.79.
Antidiabetic Activity of Ethanol-Water Fraction of Longjack Root (Eurycoma longifolia Jack.) in Streptozotocin-Nicotinamide Induced Rats Wiwik Hartika; Michelle Terrence; Ikhsan Samir; Ruqiah Ganda Putri Panjaitan
Jurnal Penelitian Pendidikan IPA Vol 10 No 2 (2024): February
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v10i2.4759

Abstract

This study aims to determine the decrease in glucose levels, MDA levels, and histopathological appearance of the pancreatic organs of Wistar white rats after administration of the ethanol-water fraction of longjack root. This study used a completely randomized design with four treatment groups and six replications. The treatment consisted of normal control, negative control (Na-CMC 0.5% 5 ml/200 g body weight), positive control (glibenclamide 0.09 mg/200 g body weight), and treatment of the ethanol-water fraction of longjack root with a dose of 500 mg/kg body weight. The results showed that the ethanol-water fraction of longjack root at a dose of 500 mg/kg body weight had antidiabetic activity comparable to that of glibenclamide at a dose of 0.09/200 g body weight, namely blood glucose levels and MDA levels in white rats of 123.55 mg/dl and 2.83 nmol/ml. The results of histopathological analysis of the pancreas of white rats showed that administration of the ethanol-water fraction of longjack root could repair damage to the islets of Langerhans due to the administration of streptozotocin-nicotinamide.