Nena Vauziah Sary
Universitas Singaperbangsa Karawang

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ANALISIS CEMARAN LOGAM BERAT TIMBAL (Pb) PADA MAKANAN DAN MINUMAN : STUDI LITERATUR Audi Ichsani Aribowo; Bunga Nur Annisa; Nena Vauziah Sary; Lina Nurfadhila; Marsah Rahmawati Utami
Jurnal Penelitian Farmasi & Herbal Vol 5 No 1 (2022): JURNAL PENELITIAN FARMASI & HERBAL
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v5i1.1038

Abstract

Heavy metals are defined as the transition elements that have a high atomic mass, are toxic, and cannot be broken down by living organisms. Metal Lead (Pb) is one of the heavy metals which are widely distributed in the environment. Heavy metal lead is one of the causes of serious health problems because it can cause disturbances to the human body. Therefore, the aim of this literature review is to present an illustration and up-to-date data on the analytical methods used for food and beverages contaminated with lead heavy metal (Pb). The methodology of this research is a literature review study from several databases such as Science Direct, Pubmed, and Google Scholar with a limitation of publication in the last 10 years. The results of a literature review from the analysis of Pb metal contamination in food and beverages, there are several techniques that can be utilized to analyze and various factors that cause the amount of lead (Pb) levels such as the atomic absorption spectrophotometer (AAS) method.
TINJAUAN PUSTAKA EVALUASI FARMAKOVIGILANS OBAT ANTIDIABETES ORAL PADA PASIEN RAWAT JALAN DIABETES MELITUS TIPE II Nena Vauziah Sary
Jurnal Penelitian Farmasi & Herbal Vol 5 No 1 (2022): JURNAL PENELITIAN FARMASI & HERBAL
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Diabetes Mellitus can be treat with pharmacological therapy in the form of oral drug administration. This step has side effects in the form of adverse drug reactions. ADR adapts various factors that can influence the patient to adverse reactions.The purpose of this study was to determine the percentage of incidence of ADR in outpatients with type II diabetes mellitus. This research method is a literature study method searched through PubMed, Google Scholar, and Research Gate using the keywords pharmacovigilance, diabetes mellitus, and adverse drug reaction (ADR). The criteria for articles used were publish in the last 10 years, namely 2012 to 2022, the journal has a title and content that is in accordance with the research objectives. The occurrence of ADR was influence by the gender and type of drug taken. This is in accordance with the research. Oral hypoglycemic drugs that were suspect to be the cause of the onset of ADRs are metformin causing nausea effects and acarbose causing flatulence effects. The use of the Naranjo algorithm is indispensable for assessing the severity of the ADR. Keywords: Farmakovigilans., Diabetes Melitus, ADR