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All Journal ALCHEMY Jurnal Penelitian Kimia Jurnal Perikanan
Aisyah Aisyah
Universitas Padjadjaran
Agriculture, Biological Sciences & Forestry Chemical Engineering, Chemistry & Bioengineering Chemistry Energy Environmental Science Materials Science & Nanotechnology

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PENGARUH INDUKSI PROBIOTIK Bacillus CgM22 PADA PAKAN TERHADAP PERTAMBAHAN BOBOT IKAN DAN MORFOMETRIK VILLI USUS IKAN MAS (Cyprinus carpio) Kiki Haetami; Yuniar Mulyani; Aisyah Aisyah
Jurnal Perikanan Unram Vol 12 No 3 (2022): JURNAL PERIKANAN
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jp.v12i3.342

Abstract

Ikan mas (Cyprinus carpio) merupakan jenis ikan air tawar budidaya paling penting, sehingga performa pertumbuhan diharapkan terus meningkat. Tujuan penelitian adalah untuk menganalisis induksi Bacillus CgM22 sebagai probiotik terhadap pertumbuhan mutlak dan morfometrik villi usus pada mas (Cyprinus carpio).  Penelitian terdiri dari tahapan, (1) Pengambilan mikroba usus dan uji proteolitik, (2) Pemeliharaan ikan Mas (Cyprinus carpio) dengan induksi oral melalui pakan di Laboratorium Akuakultur FPIK Unpad, dan (3) Pembuatan preparat histologi anterior usus dan pengukuran villi usus, yang dilaksanakan di Laboratorium Biosistem Fakultas Biologi Unpad. Feeding trial dilakukan secara eksperimental menggunakan Rancangan Acak Lengkap (RAL), dengan empat perlakuan induksi probiotik dari supernatan Bacillus CgM22 pada pakan dengan dosis masing-masing 0, 5, 10, dan 15 ml/kg, yang diulang sebanyak tiga kali. Berdasarkan hasil pengukuran pertambahan bobot dan morfometrik vili usus pada ikan mas didapatkan bahwa perlakuan C (induksi Bacillus CgM22 dosis 10 ml/ kg pakan) memperlihatkan kedalaman dan panjang crypta dan menghasilkan pertumbuhan bobot mutlak tertinggi 8, 8 gr, dengan bobot akhir sebesar 12,8 g.
Antibacterial Activity of Avicennia Mangrove Yeni Mulyani; Yuniar Mulyani; Aisyah Aisyah
ALCHEMY Jurnal Penelitian Kimia Vol 21, No 2 (2025): September
Publisher : UNIVERSITAS SEBELAS MARET (UNS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/alchemy.21.2.100706.180-197

Abstract

The rise of antibiotic resistance presents a major challenge, reducing the efficacy of conventional antibacterial treatments and necessitating the discovery of novel antimicrobial agents. The use of natural products has played a pivotal role in the development of antibiotics. Specifically, marine organisms, with a notable emphasis on mangroves of the genus Avicennia, have played a crucial role in this process. Avicennia marina, Avicennia officinalis, Avicennia alba, and Avicennia germinans have been found to contain secondary metabolites, including flavonoids, tannins, alkaloids, and terpenoids, which exhibit antibacterial properties against drug-resistant pathogens. The review was conducted based on literature published between 2005 and 2025. These compounds act through diverse mechanisms such as disrupting bacterial cell walls, inhibiting protein synthesis, and interfering with quorum sensing and biofilm formation. Evaluations through disk diffusion, microdilution assay, and biofilm inhibition assays have demonstrated the significant antibacterial activity of Avicennia extracts, suggesting their potential as alternative therapeutics in combating resistant bacteria. Future research should focus on enhancing these bioactive compounds’ bioavailability, stability, and large-scale production while addressing potential toxicity and navigating the complex regulatory requirements for drug approval. The continued exploration of Avicennia-derived compounds may contribute to developing novel antibiotics, offering sustainable solutions to antibiotic resistance.
Co-Authors Kiki Haetami Yeni Mulyani Yuniar Mulyani