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All Journal Jurnal Insan Farmasi Indonesia Media Farmasi Indonesia
Eka Susanti Hanhadyanaputri
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Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology Physics Other

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PERBEDAAN AKTIVITAS ANTIOKSIDAN PADA KOLANG KALING SEGAR DAN KOLANG KALING SERBUK Eka Susanti Hanhadyanaputri; Ariani Hesti Wulan; Indah Sulistyarin; Intan Martha Cahyani
Jurnal Insan Farmasi Indonesia 2023: JIFI: Webinar & call for paper
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v6i3.1704

Abstract

Kolang kaling (Arenga pinnata) is one of the results of the palm tree. The process of processing palm fruit into and fro can affect the quality of the fruit and fro produced.  The purpose of this study was to determine the physico-chemical characteristic, IC 50 value of fresh fruit and fro, the powder was dried in the microwave at low temperature (40oC) for 5 days, medium (53oC) for 4 hours and high (78oC) for 2 hours, and to find out whether there are effect of difference in fresh fruit and fro treatment on antioxidant activity.  Fresh fruit and fro were tested for phytochemical screening and FTIR, physicochemical characteristics and antioxidant, Antioxidant testing used the DPPH (1,1-diphenyl-2-picrylhidrazyl) method. The results of phytochemical screening and FTIR showed the presence of galactomanan compounds.  The antioxidant test results obtained the IC50 value of fresh fruit and fro, the powder was dried in the microwave at low temperature, medium and high respectively 104.8488; 25.2963; 90.0155 and163.4381 ppm. The statistical test results showed a value of 0.000<0.05,  there is a difference IC50 between groups
The The Effect Of Watermelon Seed (Citrullus Lanatus (Thunb) Mansf.) Ethanol Extract Concentration And Soaking Duration On The In Vitro Dissolution Of Calcium Kidney Stones Suprijono, Agus; Eka Susanti Hanhadyanaputri; Nia Dewi Kumalasari
Media Farmasi Indonesia Vol. 20 No. 2 (2025): Media Farmasi Indonesia
Publisher : SEKOLAH TINGGI ILMU FARMASI YAYASAN PHARMASI SEMARANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53359/mfi.v20i2.346

Abstract

Kidney stones are a collection of mineral salts such as uric acid, phosphate, and calcium oxalate that form from substances that accumulate along the urinary tract. Kidney stones can cause pain in the back, waist, and lower abdomen. Therefore, efforts are needed to dissolve kidney stones, one of which is with watermelon seeds. Watermelon seeds contain flavonoids that are thought to be able to dissolve calcium kidney stones. The aims of this research was to determine whether the concentration of watermelon seed extract and the duration of soaking calcium kidney stones can dissolve calcium kidney stones in vitro. The object of the research was the concentration of calcium kidney stones dissolved after the addition of watermelon seed extract. Watermelon seed powder was extracted using a maceration method with 70% ethanol solvent, then make watermelon seed extract concentrations of 2%, 4%, and 6% and the kidney stones were soaked in the watermelon seed ethanol extract concentration for 3 and 5 hours. Analysis of the dissolved calcium kidney stones was measured used the Atomic Absorption Spectrophotometer method. Identification of the type of kidney stone was carried out used an FTIR spectrophotometer. The result research shows that watermelon seed extract with a concentration of 2%, 4%, and 6% can dissolve calcium kidney stones with a 3-hour soaking duration of 24.34 ppm, 69.87 ppm, and 137.06 ppm on average, while a 5-hour soaking duration of 31.61 ppm, 82.27 ppm, and 140.82 ppm on average. Statistical tests show that there is an effect of extract concentration and soaking time of kidney stones in dissolving calcium kidney stones in vitro and the longer the soaking time the larger the kidney stones that can be dissolved
Co-Authors Agus Suprijono Ariani Hesti Wulan Indah Sulistyarin Intan Martha Cahyani Nia Dewi Kumalasari