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All Journal Jurnal Penelitian Pendidikan IPA (JPPIPA) Science Midwifery Indonesian Journal of Global Health research
Kelvin Kelvin
Tarumanagara University
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Dentistry Education Health Professions Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Nursing Physics Public Health Veterinary

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The Role of Essential Oils on Improving Elderly Skin Hydration Linda Julianti Wijayadi; Kelvin Kelvin
Science Midwifery Vol 10 No 4 (2022): October: Science Midwifery
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v10i4.769

Abstract

Skin hydration has an important role in various diseases of the elderly. Skin hydration is determined by two factors, namely the ability of the stratum corneum (SC) to retain water due to natural moisturizing factors and the barrier function of the intercellular lipid lamellar structure and tight junctions. Several parameters are usually used for skin hydration, such as surface water content (SWC) and trans-epidermal water loss (TEWL). With age, several changes in the skin affect hydration, including changes in the cellular and intercellular lipid matrix, skin pH, SC protease enzymes, decreased sebaceous and sweat gland activity, and decreased estrogen levels in women. Therefore, a moisturizer is needed to minimize the unwanted effects of some of these changes. Selection of the type of moisturizer is very important for the elderly, especially moisturizers with antiseptic, antibacterial, and antioxidant effects are highly recommended. The ability of essential oils as components of moisturizers has been proven in various studies. Essential oils can improve the function of the epidermal barrier and help prevent transepidermal water loss. Therefore, this literature review discusses the role of various essential oils, namely green tea oils (Camellia sinensis or Camellia assamica), virgin coconut oils (Cocos nucifera L.), evening primrose oils (Oenothera paradoxa), grape seed oils (Vitis vinifera L.) .), rosemary oils (Rosmarinus officinalis L.), immortelle oils (Helichrysum italicum), and cannabis seeds oils (Cannabis sativa L.) on improving skin hydration in the elderly.
Effects of Stem Cell Therapy on Keloid Treatment: A Literature Review Eric Eric; Maria Olivia Angeline; Belinda Layrenshia; Kelvin Kelvin; Louis Rianto; Nadya Nainggolan; Cindy Willyana; Shamyra Radiance; Rizka Saffana Alinda Putri
Jurnal Penelitian Pendidikan IPA Vol 10 No 6 (2024): June
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v10i6.3865

Abstract

Fibroblasts that produce excess collagen and growth factors play a role in the pathogenesis of keloid formation. In general, keloids are treated with intralesional corticosteroids alone or with a combination of other modalities, but the recurrence rate is still relatively high, so alternative treatments such as stem cells are being investigated, one of which is Mesenchymal Stem Cells (MSC), which have proven to be useful in healing keloids. Therefore, this literature review aims to discuss the effects of stem cell therapy in the treatment of keloids. In this literature review, 36 journals were used that discussed stem cell therapy in the treatment of keloids taken from various journal sources, namely Google Scholar, Pubmed, Medline, Ebsco, Hindawi, and Cochrane which were published within the last 10 years. According to the source, MSC is divided into 2 types, namely Adipose Mesenchymal Stem Cells (AMSC) and Bone Marrow Mesenchymal Stem Cells (BMMSC). In several studies, AMSC is known to reduce the expression of TGF-β1, COL-1, and COL-2 proteins, and has been shown to inhibit the proliferation of fibroblasts in keloid patients. Whereas in the BMMSC study that was applied with Hydroxybutyl chitosan (HBC) and Arg-Gly-Asp (RGD) hydrogels for 7 days, it was shown to significantly reduce nodular collagen fibers (p<0.05). Keloids occur due to excessive production of collagen and are influenced by various factors such as age, gender, skin color, and genetics. Stem cell therapy, such as MSC, has been proven in various studies to be an alternative treatment for keloids
Management of Cutaneous Wounds with Herbal Essential Oils Linda Julianti Wijayadi; Kelvin Kelvin; Evan Dionesia Gravianto; Fransisca Nathalia Cindy Kartawijaya
Indonesian Journal of Global Health Research Vol 6 No 6 (2024): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v6i6.4323

Abstract

In order to improve the effectiveness of cutaneous wound healing, various efforts have been made. Multiresistant bacteria are one of the challenges of wound healing treatment. Herbal essential oil is one of the alternatives that can be used, because of its broad-spectrum antimicrobial effects. The purpose of this literature review is to discuss in more depth the role of herbal essential oils in wound healing. Articles were retrieved from several databases such as Google Scholar, Sciencedirect, Cochrane, and Pubmed. Articles were searched using predetermined keywords, which were then screened from 2014-2024, resulting in 11 articles that met the inclusion criteria. The herbal essential oils discussed, namely immortelle essential oil, lavender essential oil, tea tree essential oil, chamomile essential oil, calendula essential oil, and castor essential oil, have been shown to be significantly beneficial in wound healing in studies on mice. The herbal essential oils are expected to be an alternative treatment in wound healing, especially in humans.
Co-Authors Belinda Layrenshia Cindy Willyana Eric Eric Evan Dionesia Gravianto Fransisca Nathalia Cindy Kartawijaya Louis Rianto Maria Olivia Angeline Nadya Nainggolan Rizka Saffana Alinda Putri Shamyra Radiance Wijayadi, Linda Julianti