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Uwe Wollina
Department of Dermatology and Allergology, Städtisches Klinikum Dresden, Academic Teaching Hospital, Dresden, Germany
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Physics Public Health

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Acceptance and willingness to purchase a hypothetical COVID-19 vaccine in a region under Shariah law: A cross-sectional study in Aceh, Indonesia Muhammad A. Rayhan; Mudatsir Mudatsir; Nurjannah Nurjannah; Ichsan Ichsan; Mehrdad Amir-Behghadami; Yousef S. Khader; Ai Koyanagi; Ranjit Sah; Sandro G. Viveiros-Rosa; Mohammed A. Mamun; Yohannes K. Lemu; Assarag Bouchra; Laure SG. Linguissi; Aamer Ikram; Dina E. Sallam; Konstantinos Parperis; Uwe Wollina; Marius Rademaker; Sandro Vento; Said Usman
Narra J Vol. 2 No. 2 (2022): August 2022
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v2i2.85

Abstract

Vaccines are urgently needed to control the coronavirus disease 2019 (COVID-19) pandemic. The aim of this study was to determine the acceptance of and willingness to purchase a hypothetical COVID-19 vaccine in the general population of Aceh, a holistic Shariah law implementation province in Indonesia. An online cross-sectional study was conducted using a quota sampling technique between 1 to 24 September 2021. To determine hypothetical vaccine acceptance, respondents were asked if they were willing to accept vaccines with combinations of either 50% or 95% effectiveness and either 5% or 20% risk of adverse effects. Willingness to purchase was assessed by asking whether the participants would pay for such vaccines at certain price points. Logistic regression analysis was used to assess the associated determinants. Out of 377 respondents included in the final analysis, 86.5% were willing to accept a COVID-19 vaccine with 95% effectiveness and 5% adverse effects. The acceptance rate dropped to 45.1% if the risk of adverse effects was 20%. Vaccines with 50% effectiveness and 5% adverse effects were acceptable to 42.2% but the acceptance went down to 17.2% if the risk of adverse effects increased to 20%. Multivariate analysis found that men were twice as likely to accept a vaccine with 95% effectiveness and 5% adverse effects compared to females (aOR: 2.01; 95% CI 1.05–3.86). We found that 156/377 (41.3%) of respondents were willing to purchase a COVID-19 vaccine and of these participants 71.1% were willing to pay between Indonesian Rupiah (IDR) 50,000–150,000 (US$ 3.33–10.00). In conclusion, the acceptance rate of a hypothetical COVID-19 vaccine varied based on effectiveness and the risk of adverse effects.
Essential oils for COVID-19 management: A systematic review of randomized controlled trials Teuku F. Duta; Diva R. Rizki; Agnia Purnama; Marius Rademaker; Uwe Wollina; Yogesh Acharya; Ziad Abdeen; Sandro G. V. Rosa; Henning B. Nielsen; Kannan Subbaram
Narra X Vol. 1 No. 2 (2023): August 2023
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narrax.v1i2.84

Abstract

Essential oils can be a beneficial adjuvant therapy in managing coronavirus disease 2019 (COVID-19). This systematic review aims to evaluate the efficacy of essential oils in ameliorative COVID-19-related symptoms. Published studies reporting the efficacy of essential oils as adjuvant therapy for COVID-19 were screened on Scillit, Scopus, SciFinder, and PubMed (December 7th, 2022). Inclusion criteria include the randomized controlled trials (RCTs) participated by those diagnosed with COVID-19 and treated with essential oils as adjuvant therapy. Quality assessment was carried out using Cochrane ‘risk-of-bias’ 2.0 tool. A total of 2112 records were retrieved from the initial screening, which was reduced to four publications (n=344 individuals). The foregoing studies reported that essential oils could improve the recovery rate, alleviate post-COVID-19 fatigue, and prevent disease progression. Regarding their potential antiviral activity, better designed studies are needed. In conclusion, essential oils as adjuvant therapy are beneficial in ameliorating mild COVID-19 symptoms.
Co-Authors Aamer Ikram Agnia Purnama Ai Koyanagi Assarag Bouchra Dina E. Sallam Diva R. Rizki Henning B. Nielsen Ichsan Ichsan Kannan Subbaram Konstantinos Parperis Laure SG. Linguissi Marius Rademaker Marius Rademaker Mehrdad Amir-Behghadami Mohammed A. Mamun Mudatsir Mudatsir Muhammad A. Rayhan Nurjannah Nurjannah Ranjit Sah Said Usman Sandro G. V. Rosa Sandro G. Viveiros-Rosa Sandro Vento Teuku F. Duta Yogesh Acharya Yohannes K. Lemu Yousef S. Khader Ziad Abdeen