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All Journal JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Majalah Farmaseutik
Ika Puspita Sari
Departemen Farmakologi dan Farmasi Klinik, Fakultas Farmasi, Universitas Gadjah Mada
Health Professions Medicine & Pharmacology Public Health

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Hubungan Tingkat Pengetahuan dan Kepatuhan Terhadap Luaran Klinik Pasien Diabetes Mellitus melalui Metode Brief Counseling di Puskesmas di Kabupaten Pemalang Nanang Munif Yasin; Irrene Wulan Syafitri; Ika Puspita Sari
Majalah Farmaseutik Vol 18, No 4 (2022): in press
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/farmaseutik.v18i4.74919

Abstract

Pandemi COVID-19 menyebabkan terjadinya penurunan interaksi kegiatan rutin PROLANIS pasien Diabetes Mellitus  (DM) tipe 2 di fasilitas kesehatan tingkat pertama. Tujuan dari penelitian ini adalah untuk mengetahui hubungan tingkat pengetahuan dan kepatuhan terhadap luaran klinik pasien DM tipe 2 setelah pemberian brief counseling oleh apoteker. Jenis penelitian ini adalah quasi-experimental dengan metode pretest and posttest design with control group. Penelitian ini dilakukan secara prospektif untuk menganalisis hubungan tingkat pengetahuan dan kepatuhan terhadap luaran klinik pasien Diabetes Mellitus setelah pemberian brief counseling. Tingkat pengetahuan diukur menggunakan kuesioner Diabetic Knowledge Questionnaire-24 (DKQ-24), tingkat kepatuhan diukur menggunakan kuesioner Morisky Green Levine Scale (MGLS), dan luaran klinik pasien DM tipe 2 berupa glukosa darah puasa (GDP) di Puskesmas di Kabupaten Pemalang pada periode Oktober hingga November 2021. Analisis data karakteristik subjek penelitian menggunakan metode deskriptif dan disajikan dalam bentuk presentasi dan frekuensi. Analisis untuk mengetahui hubungan antara tingkat pengetahuan dan kepatuhan terhadap luaran klinik menggunakan uji chi-square dengan tingkat kepercayaan 95% (α = 0,05). Penelitian ini terdiri dari 32 pasien pada masing-masing kelompok kontrol dan intervensi. Hasil analisis deskriptif penelitian ini menunjukkan tidak terdapat perbedaan data karakteristik subjek penelitian pada kelompok kontrol dan intervensi (p>0,05).  Hasil analisis bivariat terkait korelasi menunjukkan adanya hubungan antara tingkat pengetahuan terhadap luaran klinik (p=0,000), dan tingkat kepatuhan terhadap luaran klinik pasien DM tipe 2 (p=0,000). Berdasarkan hasil penelitian tersebut, dapat disimpulkan bahwa ada hubungan yang bermakna antara tingkat pengetahuan dan kepatuhan terhadap luaran klinik pasien DM tipe 2 setelah pemberian brief counseling oleh apoteker.
Evaluation the Rationality of Clinical Outcomes of Antibiotic Use and Patterns of Bacterial Resistance to Antibiotics in Children with Pneumonia Cindy Elvionita; Ika Puspita Sari; Titik Nuryastuti
Majalah Farmaseutik Vol 19, No 1 (2023)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/farmaseutik.v19i1.76103

Abstract

Pneumonia is a respiratory infection that attacks the lungs in the lung parenchyma tissue or alveoli. Pneumonia is one of the leading causes of death in children worldwide. Rational use of antibiotics can reduce the risk of antibiotic resistance. This study used observational analytics with a retrospective cohort design. The research subjects were pediatric patients with a diagnosis of pneumonia who were hospitalized at Dr. Sardjito Yogyakarta period 1 January – 31 December 2020. The rationality of the use of antibiotics was evaluated using the Gyssens method. The clinical outcome observed was the patient's condition improving or not improving after 3 to 5 days of antibiotic administration. Chi-Square test to see the relationship of antibiotic rationality to clinical outcomes and multiple logistic regression analysis to analyze the relationship of confounding variables to clinical outcomes. From 141 patients, 211 antibiotic regimens were obtained, with details of 186 empiric antibiotics and 25 definitive antibiotics. The rational use of antibiotics in empirical and definitive antibiotics was 140 regimens (75.27%) and 22 regimens (88%). Total irrational antibiotics (category I-VI) from empirical and definitive antibiotics were 24.73% and 12%, respectively. There is a significant relationship between the rationality of antibiotics with clinical outcomes both empirical and definitive antibiotics (p<0.05). Meanwhile, for confounding variables, there was no significant relationship to the clinical outcome (p>0.05). The most common bacteria were Klebsiella pneumoniae and Acinetobacter baumanii. Klebsiella pneumoniae was the most resistant to ampicillin, ampicillin sulbactam and ceftriaxone antibiotics and Acinetobacter baumanii was the most resistant ampicillin.
Pengaruh Edukasi oleh Apoteker dengan Metode Brief Counseling terhadap Pengetahuan, Kepatuhan dan Glukosa Darah Pasien DM Tipe 2 di Puskesmas Kabupaten Pemalang Irrene Wulan Syafitri; Nanang Munif Yasin; Ika Puspita Sari
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 13, No 1
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.74821

Abstract

The problem currently encountered by Diabetes Mellitus (DM) patients is a decrease interaction in routine activities carried out at first-level health facilities due to the Covid-19 pandemic. This study is to determine the effect of education by pharmacists with media brief counseling on the knowledge, compliance, and clinical outcomes of DM patients. This type of research is a quasi-experimental method with a pretest and posttest design with the control group. This study was conducted prospectively to analyze the effect of brief counseling-based pharmaceutical services by pharmacists on the level of knowledge measured using the Diabetic Knowledge Questionnaire-24 (DKQ-24), the level of compliance was measured using the Morisky Green Levine Scale (MGLS) questionnaire, and the clinical outcomes of type 2 DM patients at the Puskesmas in Pemalang Regency from October to November 2021. The analysis to measure the bivariate differences in one group used the paired sample t-test, and the bivariate differences between groups were measured using the independent sample t-test. This study consisted of 32 patients in each control and intervention groups. The descriptive analysis of this study showed no differences in data on patient characteristics in the control and intervention groups (p>0.05). The results showed that there was an increase in patient knowledge from 12,66±2,43 to 21,75±1,81 (p=0,000) and an increase in patient compliance from 2,03±0,96 to 0,25±0,51 (p=0,000) after being given brief counseling. The clinical outcomes of DM patients showed that there was an improvement from 177,63±82,4 to 159±58,1 (p=0,002). Based on these results, it can be concluded that there is an effect of education by a pharmacist using the brief counseling method on the level of knowledge, compliance, and clinical outcome of type 2 DM patients.
Perbandingan Luaran Klinis Favipiravir dan Remdesivir pada Pasien Covid-19 Derajat Sedang di RS Akademik UGM Yogyakarta Hadiatussalamah Hadiatussalamah; Tri Murti Andayani; Ika Puspita Sari
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 13, No 3
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.84815

Abstract

Research on effective antivirals for COVID-19 is still ongoing. Favipiravir and remdesivir are antivirals that have been recommended in Indonesia. This study aimed to compare the clinical outcomes of favipiravir and remdesivir in moderate COVID-19 patients. This research is a retrospective cohort study conducted at the UGM Academic Hospital Yogyakarta using electronic medical records of moderate COVID-19 who were hospitalized from June 2021 to March 2022. Each therapy group consisted of 88 subjects. Clinical outcomes in the form of improved and not-improved conditions were assessed using a 7-point ordinal scale of progressivity and recovery of COVID-19 from WHO. Chi-square analysis and multiple logistic regression were performed to determine the relationship between the research variables. The highest percentage of research subjects were aged 18 – 59 years (70,5%), male (53,4%), and not obese (64,2%). The most common comorbidities were diabetes mellitus (33%) and hypertension (30%). The favipiravir group had a better clinical outcome than remdesivir. The proportion of patients improving in the favipiravir group was 50,0% and 35,3% in the remdesivir group (p-value=0,048). There was no significant difference in the number of adverse events between both study groups (p-value > 0,05). The most common adverse drug events were nausea (35,2%), vomiting (14,2%), and heartburn (11,4%).  
Co-Authors Cindy Elvionita Hadiatussalamah Hadiatussalamah Irrene Wulan Syafitri Nanang Munif Yasin Titik Nuryastuti Tri Murti Andayani