Muflihatul Muniroh
Department of Physiology, Faculty of Medicine, Diponegoro University, Semarang

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Relationship of Sleep Quality with Short-Term Memory and Reaction Time in First Year Medical Students of Diponegoro University Rizki Gatot Febrian; Santoso Jaeri; Muflihatul Muniroh; Darmawati Ayu Indraswari
JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 10, No 5 (2021): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v10i5.31391

Abstract

Abstract Background: Sleep disturbance is a disorder that includes a lack of quantity and quality of sleep. Students, especially medical students, have a high risk of getting sleep disorders of poor sleep quality and quantity. Poor sleep quality can interfere with memory. Besides, poor sleep quality also results in fatigue, which can lead to increased reaction time.Aim: To determine the relationship between sleep quality and short-term memory and reaction time in first-year medical students of Diponegoro University.Methods: This Observational study used a cross-sectional design with first-year medical students of Diponegoro University as the subjects. Kolmogorov-Smirnov was applied as the normality test, then the hypothesis test between sleep quality and short-term memory used the Pearson Chi-Square test, while sleep quality and reaction time used the Mann-Whitney U test. Results: Two hundred students participated in the study. Eighty two people (41%) had good sleep quality, 118 people (59%) had poor sleep quality. The p value of the relationship between sleep quality and short-term memory showed insignificant result (p=0.791). Meanwhile, the Mann-Whitney test to measure the relationship between sleep quality and reaction time was also insignificant (p=0.270).Conclusion: There is no significant relationship between sleep quality with reaction time and short-term memory in first-year medical students of Diponegoro University.
ANTIHYPERURICEMIC EFFECT OF RED GINGER POWDER AND LIME JUICE COMBINATION IN WISTAR RATS INDUCED HYPERURICEMIA Eva Susanty Purba; Chikita Dian Rahma Saphira; Salma Yasmine Azzahara; Edwin Basyar; Muflihatul Muniroh; Ainun Rahmasari Gumay
JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 10, No 1 (2021): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v10i1.29374

Abstract

Background: Hyperuricemia is an abnormally high level of uric acid in the blood. Ginger and lime are natural ingredients that contain antioxidants and anti-inflammatory which could reduce blood uric acid levels. This study aims to prove the effect of red ginger powder and lime juice combination on uric acid levels of Wistar rats induced hyperuricemia.Methods: Experimental research with pre and post-test only control group design. Thirty Wistar male rats, aged 2-3 months, weighed 150-350 grams randomly divided into 5 groups. Group C1 was normal control group. Group C2 was induced by single intraperitoneal injection of potassium oxonate (300mg/kgBW). Group T1, T2, T3 were induced by potassium oxonate and orally administered by combination of red ginger powder (300, 600, 1200 mg/200gBW) and lime juice (2ml/150gBW). Blood samples in each group will be collected in 1 hour after treatment. Uric acid levels were measured using the TBHBA uric acid method.Results: Uric acid level in T1, T2, and T3 group was significantly lower than C2 group (p<0,05). The most effective dose to reduce uric acid levels was 1200mg/200gBW red ginger in combination with 2ml/150gBW lime juice (T3 group).Conclusion: Red ginger powder and lime juice may reduce the blood uric acid levels in Wistar rats induced hyperuricemia.
Effect of Clitoria Ternatea as Adjuvant Therapy on Serum Cortisol Levels in Leprosy Reaction Rina Purnamasari; Muflihatul Muniroh; Novi Kusumaningrum; Farmaditya EP Mundhofir; Renni Yuniati
Jurnal Aisyah : Jurnal Ilmu Kesehatan Vol 8, No 1: March 2023
Publisher : Universitas Aisyah Pringsewu

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (632.391 KB) | DOI: 10.30604/jika.v8i1.1502

Abstract

This study was to investigate the effect of using an extract from Clitoria ternatea as adjuvant therapy on the levels of blood cortisol in patient with leprosy reaction. The current investigation is an experimental study designed a single-blind randomized controlled trial comparison between two groups. The control group which received standard prednisolone therapy and the intervention group received standard prednisolone therapy and adjuvant therapy of Clitoria ternatea extract dose 2 g/day for one month. Serum levels of cortisol were measured by ELISA. The average serum level of cortisol decrease in control grup with statistically significant (p=0.008). The average serum level of cortisol increase in treatment grup with statistically significant (p=0.026) similar with average difference of both groups (p=0.02). According to the results of the study, the use of an extract from Clitoria ternatea extract 2 g / day for one month as adjuvant therapy significantly increase the serum cortisol levels in patients with leprosy reaction
Literature review: Paparan merkuri (Hg) pada anak stunting di area pertambangan emas Aisyah Aisyah; Anang M. Legowo; Muflihatul Muniroh
Jurnal SAGO Gizi dan Kesehatan Vol 5, No 3A (2024): Agustus
Publisher : Poltekkes Kemenkes Aceh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30867/gikes.v5i3A.1713

Abstract

Background: Mercury (Hg) is used by small-scale gold miners to extract gold. Mercury waste is dangerous and toxic because it pollutes the environment and living creatures. Mercury can accumulate in the body through the food chain, air and air. Children who are exposed to mercury are associated with a risk of various health problems that can result in stunting.Objective: The aim of writing this literature review is to identify exposure to mercury (Hg) in stunted children.Method: This research is in the form of descriptive analysis. This research took the form of a literature review, article synthesis was carried out in a narrative manner as recommended by the PRISMA statement in selecting the articles found. The keywords used are stunting, exposure to mercury (Hg) and gold mining areas. Literature sources were obtained from the Scopus database, Google Scholar, PubMed Central and Science Direct. Inclusion criteria are stunting, exposure to mercury (Hg) and gold mining areas, full text, published in 2013-2023. Exclusion criteria are articles in the form of books and documents, reviews, meta-analysis and systematic reviews.Results: Results from the literature show that stunted children are exposed to mercury that comes from the environment due to gold mining. Urine samples of stunted children aged 0-59 months contain mercury above 7 μg/L, which is the threshold set by Human Biomonitoring (HBM).Conclusion: Stunted children aged 0-59 months who live in gold mining areas are exposed to mercury. The risk of mercury exposure to children can come from food, water and air.KeywordsGold Mining Area, Mercury Exposure, Stunting