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All Journal Jurnal Biologi Tropis
I Made Arya Yogiswara Mahayasa
Universitas Mataram
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Immunology & microbiology

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Prognosis Comparison of Use of Oral Anticoagulants and Vitamin K Antagonists in Patients with Intracerebral Hemorrhage I Made Arya Yogiswara Mahayasa; Puspasari Mahadewi; Luthfiyah Kamila; Ayu Santia Dewi; Muhammad Faeyza; Baiq Wanda Annisa; Arif Setyo; Shania Hafista; Bagas Ekasangga; Adinda Citra; Ulfa Ramdhani; Yusuf Alfian; Arfi Syamsun
Jurnal Biologi Tropis Vol. 22 No. 4 (2022): October - December
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v22i4.4176

Abstract

This study reviewed the literature on the incidence of Intracerebral Hemorrhage (ICH) associated with the use of oral anticoagulant drugs (OAC) and vitamin K antagonists (VKA), then compared the outcomes of using these drugs in terms of mortality, morbidity or prognosis in patients. We did a search on online databases including Pubmed, Google Scholar and Science Direct according to the specified keywords. The results obtained amounted to 935 articles. From these articles, the types of research that met the inclusion and exclusion criteria were then re-screened and the final search results were obtained as many as 10 articles. The results of this study found that of the 10 articles reviewed, 8 of them showed p value > 0.05 so that there was no significant difference between the outcomes of ICH related to OAC or VKA, where outcomes were viewed from the factors of bleeding widening, ICH volume, mortality, and functional impact. Meanwhile, from 2 articles that showed significant results, it was stated that the prognosis of the incidence of ICH related to the use of OAC was better than the use of VKA. Research on ICH, research on original article types, according to predetermined keywords, is a publication in the period 2012-2022, human studies and articles can be accessed.
Relationship of Comorbidity and Age to the Severity of Clinical Symptoms of COVID-19 at Mataram University Hospital I Made Arya Yogiswara Mahayasa; Moulid Hidayat; Prima Belia Fathana; Indana Eva Ajmala
Jurnal Biologi Tropis Vol. 23 No. 1 (2023): January - March
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v23i1.4581

Abstract

COVID-19 disease is a disease that arises due to infection with the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). The purpose of this study was to determine differences in clinical symptoms in elderly and non-elderly patients, as well as patients who had comorbidities and did not have comorbidities. This research is a type of cross-sectional study that was conducted by reviewing the medical records of COVID-19 patients undergoing treatment at Mataram University Hospital in 2021. Data was collected using a consecutive sampling technique. The statistical test used is the Chi-square comparative test. To assess the relationship of age and comorbidities to the severity of symptoms in COVID-19 patients. In this study, 86 subjects were selected based on the inclusion and exclusion criteria applied. The majority of subjects were in the 15-59 year age group, namely 66 (23.3%). With male sex 51 (60.5%) people. The majority of patients with comorbidities experienced severe/critical symptoms 16 (44.4%) and patients without comorbids experienced no symptoms or experienced mild symptoms 35 (35%). The majority of elderly patients experienced severe-critical symptoms 9 (45%) and the majority of non-elderly patients experienced no symptoms or experienced mild symptoms 42 (63.6%). The results of the bivariate analysis test showed a p-value = 0.001 for comorbids with severe symptoms, and a p-value = 0.003 for age with severe symptoms. There is a significant relationship between comorbidities and age on the severity of symptoms in COVID-19 patients.
Clipping Pada Aneurisma Intrakranial I Made Arya Yogiswara Mahayasa; Ilsa Hunaifi; Stephanie Elizabeth Gunawan; Setyawati Asih Putri
Jurnal Biologi Tropis Vol. 23 No. 3 (2023): July - September
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v23i3.5174

Abstract

An aneurysm is an abnormal formation of a blood vessel. Aneurysms are divided into 4 according to their shape (saccular, microaneurysm, giant, and fusiform). The formation of an aneurysm is caused by many factors (patient risk factors, hemodynamic stress, and involvement of cytokines and inflammatory mediators as well as macrophages, T cells, and mast cells). The diagnosis of an aneurysm is carried out with the help of tools such as MRA and CT angiography. In providing management of an unruptured aneurysm, consideration is needed by taking into account many factors, to facilitate this consideration, an assessment can be carried out first, it can be carried out using a scoring system called Unruptured Intracranial Aneurysm Treatment Score (UIATS). One of the time-proven aneurysm management is to perform aneurysm clipping. Clipping has advantages such as having a low recurrence rate and has disadvantages such as being invasive with the need to perform craniotomy. Complications that can arise from doing clipping in aneurysms such as infection, allergic reactions to anesthetic drugs, stroke, seizures, cerebral edema. Prognosis of management using the clipping method is good.
Co-Authors Adinda Citra Arfi Syamsun Arif Setyo Ayu Santia Dewi Bagas Ekasangga Baiq Wanda Annisa Ilsa Hunaifi Indana Eva Ajmala Luthfiyah Kamila Moulid Hidayat Muhammad Faeyza Prima Belia Fathana Puspasari Mahadewi Setyawati Asih Putri Shania Hafista Stephanie Elizabeth Gunawan Ulfa Ramdhani Yusuf Alfian