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THE CORRELATION OF JOINT SPACE WIDTH WITH SYNOVIAL FLUID CARTILAGE OLIGOMERIC MATRIX PROTEIN LEVEL IN KNEE OSTEOARTHRITIS PATIENTS Halimah Sa'diyah; Faridin HP
Alami Journal (Alauddin Islamic Medical) Journal Vol 6 No 1 (2022): JANUARY
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/alami.v6i1.28965

Abstract

Osteoarthritis (OA) was a degenerative joint disease associated with joint cartilage damage, where the most commonly affected joints are vertebrae, pelvis, knee, and ankle. Pathomechanism of OA includes various etiologies that play a role in the balance destruction and synthesis of cartilage. Radiology examination was the most common method used to monitor the progression of OA but can not show changes in knee OA except in the advanced phase of the disease. Conventional radiology can estimate the thickness of the cartilage through measurement joint space width (JSW). One alternative method that can detect changes in the joint at an early stage of the disease is a measurement of the synthesis and degradation markers of the tissue. Cartilage oligomeric matrix protein (COMP) was one of the cartilage destruction markers of non-aggrecan and non-collagen groups, found in cartilage and other tissues. Several studies have reported the correlation between serum or synovial fluid COMP level with the radiographic progression of knee OA patients. This study aimed to assess the correlation between joint space width and synovial fluid COMP level in knee OA subjects. The study was a descriptive-analytic method with a cross-sectional design in 69 knee OA subjects. It was conducted in the rheumatology outpatient clinic of Wahidin Sudirohusodo Hospital Makassar and its networks on March-June 2015. In this study, we found a correlation between joint space width (JSW) and synovial fluid COMP level, where synovial fluid COMP levels were higher in knee OA subjects with more severe joint space width narrowing, and it was not influenced by age and obesity
Deteksi Dini dan Edukasi Komponen Sindrom Metabolik pada Masyarakat Desa Topejawa Kabupaten Takalar Sulawesi Selatan Rahma, Andi Sitti; Rahim, Rosdianah; Fitriani, Rini; Delima, Alifia Ayu; Sa'diyah, Halimah
Shihatuna : Jurnal Pengabdian Kesehatan Masyarakat Vol 3 No 1 (2023) : Juni
Publisher : FKM UIN Sumatera Utara Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30829/shihatuna.v3i1.13515

Abstract

Kejadian sindrom metabolik dengan segala efek negatifnya bagi kesehatan masih tinggi di Indonesia. Masyarakat belum sepenuhnya menyadari tentang bahaya, gejala dan penyebab sindrom metabolik. Tujuan kegiatan ini adalah mendeteksi secara dini kejadian sindrom metabolik dan memberikan edukasi kepada masyarakat tentang sindrom metabolik. Kegiatan ini dilakukan di Desa Topejawa Sulawesi Selatan. Kegiatan ini diikuti oleh 60 peserta dengan kelompok usia terbanyak adalah 41-50 tahun dan 51-60 tahun. Pada kegiatan ini ditemukan sebanyak 51,67% mengalami sindrom metabolik dengan obesitas sentral sebagai komponen sindrom metabolik terbanyak (70%). Edukasi yang diberikan bertujuan meningkatkan pengetahuan masyarakat tentang gejala, bahaya, dan penyebab sindrom metabolik, sehingga diharapkan masyarakat memperbaiki pola makan dan meningkatkan aktifitas fisik guna mencegah terjadinya sindrom metabolik beserta komplikasinya.
Hubungan Pengetahuan dan Tingkat Kecemasan Orang Tua terhadap Vaksinasi Covid-19 pada Anak Siti Khodijah Nur'Aini Jusuf; Azizah Nurdin; Andi Irhamnia Sakinah; Halimah Sa’diyah
Majalah Kedokteran Indonesia Vol 73 No 6 (2023): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.73.6-2024-987

Abstract

Introduction: The COVID-19 vaccine is crucial as a preventive measure against infection with the SARS-CoV-2 virus. The Indonesian Pediatric Association (IDAI) has approved the vaccination for children under 12 years, allowing them to receive up to the second dose. However, a lack of knowledge about the vaccine has led to hesitancy among parents, fueled by misinformation and concerns about potential side effects on their children. This study aims to explore the correlation between parental knowledge and their anxiety levels concerning the COVID-19 vaccination for their children.Methods: We conducted a cross-sectional survey with 207 parents of students from SDIT Nurul Fikri in Makassar City. The research instrument was a structured questionnaire. Data were analyzed through univariate analysis, followed by bivariate comparisons using the Chi-square test and multivariate regression.Results: Among the respondents, a majority (58%) exhibited limited knowledge of COVID-19, with 50.2% reporting varying degrees of anxiety about the vaccination for their children. Of the children, 46.3% had received the complete vaccination series. Statistical analysis revealed a significant correlation between parental knowledge and anxiety levels regarding their child’s COVID-19 vaccination (α less than 0.05; p=0.007).Conclusion: There is a significant correlation between knowledge and anxiety concerning children's COVID-19 vaccination, with knowledge being the most significant predictor of anxiety levels.