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Role of Radiotherapy in Gestational Trophoblastic Neoplasia: A Case Report Arie Munandar; Viona Viona
Radioterapi & Onkologi Indonesia Vol 13, No 1 (2022): Volume 13 No.1 January 2022
Publisher : Perhimpunan Dokter Spesialis Onkologi Radiasi Indonesia (PORI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32532/jori.v13i1.143

Abstract

Gestational trophoblastic neoplasia (GTN) is a placental tissues malignancy that is prone to massive bleeding. Multimodality treatment is often needed to treat GTN, such as surgery and radiotherapy. Radiotherapy has a palliative role in case of hemorrhage and/or intracranial metastases.Radiotherapy is effective in controlling bleeding by destructing malignant blood vessels by inducing endothelial damage and increasing signal transduction pathway leading to apoptosis and increasing adhesion of thrombocytes to vascular endothelia resulting fibrosis. No dose and fractionation schemes are proven more effective than others, but longer fractions scheme (>5 fractions) and BED10 > 39 Gy show no additional benefit in hemostatic control or in reduction of re-bleeding rate.Brain metastatic lesions are prone to bleeding that might need craniotomy for blood evacuation or brain decompression. WBRT can be given concurrently with chemotherapy in brain metastatic GTN cases. Higher WBRT total dose (>22 Gy) associated with higher 5-year local control rates.
PENGEMBANGAN KOMIK DIGITAL SEBAGAI MEDIA PEMBELAJARAN AGAMA BUDDHA DI VIHARA GRHA BUDDHA MANGGALA BATAM Pratama, Jimmy; Viona Viona; Wibowo, Tony
TEKNIMEDIA: Teknologi Informasi dan Multimedia Vol. 5 No. 1 (2024): Juni 2024
Publisher : Badan Penelitian dan Pengabdian Masyarakat (BP2M) STMIK Syaikh Zainuddin NW Anjani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46764/teknimedia.v5i1.163

Abstract

Vihara Grha Buddha Manggala is one of the places of worship for Buddhists in Batam, this monastery also held the Buddhist Sunday School. Buddhist Sunday School is a non-formal learning activity that are held every Sunday and is aimed for Buddhist children. With the sophistication of technology that had developed rapidly, it also impacted the diversity of forms and types of learning media, such as webtoon digital comic. By utilizing webtoon digital comic, Buddhist Sunday School students can understand the learning material better rather than through discussions and usual lectures. The aim of this research is to develop a more interesting learning media to maximize the learning activities. The result of this research is a webtoon digital comic that are designed and developed using ADDIE (Analyze, Design, Develop, Implement, Evaluate) model.