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All Journal Jurnal Farmasi Sains dan Komunitas
Muthi Ikawati
Macromolecular Engineering Laboratory, Department of Pharmacy Chemistry, Faculty of Pharmacy, Universitas Gadjah Mada, Yogyakarta 55281
Medicine & Pharmacology

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The Epigenetic Impact of Vegetables-Derived Dietary Compounds in Neurodegenerative Conditions : A Review Vania Amanda Samor; Yurida Ni'ma Annisa; Muthi Ikawati; Nunung Yuniarti
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 19, No 2 (2022)
Publisher : Sanata Dharma University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (506.281 KB) | DOI: 10.24071/jpsc.004490

Abstract

Dietary compounds from the foods we eat on a daily basis offer several benefits; they help prevent disease and preserve health. The epigenetic advantages of the vegetables we eat every day are one of the benefits that have not been well-reported. Epigenetic pathways involving histone modification, DNA methylation, and alterations caused by miRNAs are extensively engaged in signal transmission, cell development, and death in various disease states, including brain cells. Through this narrative review collected from multiple studies available on reputable online databases until March 2022 shows the epigenetic advantages of various vegetables' content such as gallic acid, quercetin, kaempferol, apigenin, luteolin, resveratrol, genistein, sulforaphane, and diallyl disulfide in neurodegenerative conditions are summarized. However, in-depth investigations are still required to clarify these epigenetic mechanisms before these compounds are ready to be used in the future, as several studies still provide contradictory results
Co-Authors Nunung Yuniarti Vania Amanda Samor Yurida Ni'ma Annisa