Hari Sukanto, Hari
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Susceptibility test of Griseofulvin, Ketoconazole, Itraconazole, and Terbinafine to Dermatophyte Species Using Microdilution Method Anggarini, Dyah Ratri; Sukanto, Hari; Astari, Linda; Endraswari, Pepy Dwi
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol 27, No 1 (2015): BIKKK APRIL 2015
Publisher : Faculty Of Medicine Airlangga University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (130.616 KB) | DOI: 10.20473/bikkk.V27.1.2015.55-62

Abstract

Backgroud: Dermatophytosis is common disease in tropical countries such as Indonesia. The prevalence of dermatophytosis in general population also high (20%). The dermatophyte fungi are the etiologic agents that cause this disease, some of them had already reported to be resistant to some anti-fungi. Purpose: To determine dermatophyte species causing dermatophytosis and the resistancy of griseofulvin, ketoconazole, itraconazole, dan terbinafine to dermatophyte species. Methods: Isolates of dermatophyte from patient who met the inclusion criteria in outpatient clinic of dermato-venereology Dr. Soetomo Hospital Surabaya during October until December 2014 were analyzed with respect to their susceptibility to four anti-fungal agents (griseofulvin, ketoconazole, itraconazole, and terbinafine) using microdilution methode. Results: Thirthy patients were included in inclusion criteria, with T. mentagrophytes var. Interdigitale was the most common cause of dermatophytoses. According to MIC all 30 isolates were already resistant to all anti-fungal agent, except T. rubrum that still sensitive to ketoconazole and 80,  itraconazole.  Conclusion: According to MIC 16.7% isolates sensitive to griseofulvin, 23.3% to ketoconazole, 16.7% to 80 itraconazole and 20% to terbinafine.Key word: dermatophyte species, susceptibility test of anti-fungal, microdilution.
Uji Tempel Pasien Dengan Riwayat Dermatitis Kontak Alergi Kosmetik di URJ Kesehatan Kulit Dan Kelamin RSUD Dr. Soetomo Surabaya Miftah, Antoni; Prakoeswa, Cita Rosita Sigit; Sukanto, Hari
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol 26, No 1 (2014): BIKKK APRIL 2014
Publisher : Faculty Of Medicine Airlangga University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (216.031 KB) | DOI: 10.20473/bikkk.V26.1.2014.1-7

Abstract

Latar belakang: Kasus dermatitis kontak alergi kosmetik (DKAK) relatif signifikan, diperkirakan 10% dari seluruh kasus dermatitis kontak di RSUD Dr. Soetomo Surabaya cenderung meningkat. Tahun 2008 ditemukan 24 (6%) penderita DKAK dari 267 pasien DKA, sedangkan tahun 2009 ditemukan 36 (15%) dari 230 pasien DKA yang datang berobat. Tujuan: Mengetahui bahan kosmetik penyebab dermatitis kontak akibat kosmetik dan mengetahui relevansi klinis hasil uji tempel. Metode: Penelitian retrospektif terhadap 30 sampel dengan riwayat DKAK periode November 2010 – November 2011 di Divisi Alergi Imunologi URJ Kulit dan Kelamin RSUD Dr. Soetomo. Uji tempel menggunakan 12 bahan standar alergen kosmetik. Hasil: Enam belas pasien dari 30 sampel (53,33%) didapatkan hasil positif dengan satu atau lebih alergen dan 14 pasien (46,67%) negatif terhadap alergen yang ditempelkan. Hasil uji tempel positif terbanyak dari 16 pasien tersebut adalah alergen pewarna rambut yaitu 13 pasien (43,3%), diikuti pewangi 6 pasien (20%) dan pengawet 5 pasien (16,7%). Simpulan: Uji tempel alergen standar kosmetik dapat digunakan sebagai pemeriksaan penunjang terhadap penderita dermatitis kontak alergi kosmetik di Divisi Alergi Imunologi URJ Kesehatan Kulit dan Kelamin RSUD Dr. Soetomo Surabaya. Kata kunci: dermatitis kontak alergi, alergen kosmetik, uji tempel, relevansi klinis.
Occupational Contact Dermatitis: Retrospective Study Witasari, Dinar; Sukanto, Hari
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol 26, No 3 (2014): BIKKK DESEMBER 2014
Publisher : Faculty Of Medicine Airlangga University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (112.237 KB) | DOI: 10.20473/bikkk.V26.3.2014.1-7

Abstract

Background: Occupational skin disease is the second largest occupational disease in Europe after musculoskeletal injury.Most common occupational skin disease is contact dermatitis as many as 70-90%. Determining the cause of contact dermatitis in occupational environment is very important to avoid causing substances and to establish healing as well as reducing the recurrence rate. Purpose: To evaluate the management of new patients with occupational contact dermatitis in Allergy Immunology Division, Dermatology and Venerology outpatient clinic Dr. Soetomo General Hospital Surabaya in period of 2010-2012. Methods: Retrospective study of new patients with occupational contact dermatitis in Allergy Immunology Division during 2010-2012. Results: New patient of occupational contact dermatitis during the period of 2010-2012 were 50 new persons, predominantly occured in male in reproductive age (25-44 year old), irritant contact dermatitis (ICD) occured more frequent than allergic contact dermatitis (ACD). The majority of subjects were factory workers, with the most suspected ingredients was chemicals. About 21.7% patients underwent patch test. The therapy mostly given were antihistamines and topical steroids. There were 46% of patients who did not visit outpatient clinic again. Conclusions: New patients of occupational contact dermatitis in Allergy Immunology Division during the period of 2010-2012 were as many as 50 new patients. Patch test should be performed to establish the diagnosis and determine the cause of contact dermatitis materials.Key words: occupational contact dermatitis, patch test, retrospective study.