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All Journal Berkala Ilmu Kesehatan Kulit dan Kelamin Medical and Health Science Journal
Troef Soemarno, Troef
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Health Professions Immunology & microbiology Public Health Social Sciences

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Ki-67 Immunohistochemistry Examination in Pityriasis Rubra Pilaris Sari, Diana Kartika; Prakoeswa, Cita Rosita Sigit; Soemarno, Troef
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol 26, No 3 (2014): BIKKK DESEMBER 2014
Publisher : Faculty Of Medicine Airlangga University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (462.156 KB) | DOI: 10.20473/bikkk.V26.3.2014.1-5

Abstract

Background: Pityriasis rubra pilaris (PRP) is a papulosquamous disorder of unknown etiology. PRP is often difficult to be distinguished with psoriasis in early phase of the disease. Purpose: To deliver information about Ki-67 immunohistochemistry examination in PRP. Reviews: The diagnosis of PRP can be established by histological examinations or even immunohistochemistry. The best treatment options are retinoids, photochemotherapy (PUVA), and antimetabolites (methotrexate). Conclusion: Immunohistochemistry examination can provide complete feature to distinguish between PRP and psoriasis because of its high specifity.Key words: Ki-67 immunohistochemistry, pityriasis rubra pilaris, diagnosis.
IMUNOHISTOKIMIA PADA KONDILOMATA AKUMINATA Widyaswari, Meidyta Sinantryana; Lumintang, Hans; Soemarno, Troef
Jurnal Ilmu Kesehatan dan Kesehatan Vol 3 No 1 (2019): February
Publisher : UNUSA Press

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Abstract

Background: Condylomata Acuminata (CA) is a sexually transmitted disease caused by the Human Papilloma Virus (HPV) type-specific and may be simultaneously co-infected with other HPV types associated with malignancy. Purpose: To differentiate between CA and histopathological of malignancy by immunohistochemistry. LiteratureReview: CA refers to benign epidermal proliferation caused by the HPV types 6 and 11, but co-infection with high- risk HPV types are common. The clinical presentation of CA can’t differentiate between benign or preneoplastik diplasia lesions. Koilocytes considered pathognomonic for HPV lesions, these findings sometimes don’t appear on CA, and histopathology was not accurate, that immunohistochemistry with MIB-1 (Ki-67) and p16 can beused. Conclusion: Immunohistochemistry examination can help differentiate the diagnosis between malignancy or non- malignancy in the case of CA.
IMUNOHISTOKIMIA PADA KONDILOMATA AKUMINATA Widyaswari, Meidyta Sinantryana; Lumintang, Hans; Soemarno, Troef
Jurnal Ilmu Kesehatan dan Kesehatan Vol 3 No 1 (2019): FEBRUARY
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v3i1.926

Abstract

Background: Condylomata Acuminata (CA) is a sexually transmitted disease caused by the Human Papilloma Virus (HPV) type-specific and may be simultaneously co-infected with other HPV types associated with malignancy. Purpose: To differentiate between CA and histopathological of malignancy by immunohistochemistry. LiteratureReview: CA refers to benign epidermal proliferation caused by the HPV types 6 and 11, but co-infection with high- risk HPV types are common. The clinical presentation of CA can’t differentiate between benign or preneoplastik diplasia lesions. Koilocytes considered pathognomonic for HPV lesions, these findings sometimes don’t appear on CA, and histopathology was not accurate, that immunohistochemistry with MIB-1 (Ki-67) and p16 can beused. Conclusion: Immunohistochemistry examination can help differentiate the diagnosis between malignancy or non- malignancy in the case of CA.
Co-Authors Cita Rosita Sigit Prakoeswa Diana Kartika Sari, Diana Kartika Hans Lumintang, Hans Meidyta Sinantryana Widyaswari, Meidyta Sinantryana