Claim Missing Document
Check
Articles

Found 2 Documents
Search

Pengaruh Stretching Exercise Terhadap Kualitas Hidup dan Status Fungsional Lansia Penderita Diabetes Mellitus Tipe 2 Isni Hijriana; Yusnita Yusnita
Ners Jurnal Keperawatan Vol 18, No 2 (2022)
Publisher : Fakultas Keperawatan Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/njk.18.2.68-75.2022

Abstract

Elderly, chronic disease, depression, health perception, dependency level, which affect the quality of life of the elderly. Various interventions are needed by the elderly to overcome the decline in mobility related to age. The purpose of this study is to identify the effectiveness of stretching exercise on the quality of life and functional status of the elderly with type 2 diabetes mellitus. test group design with one intervention group. The total sample in this study was 30 elderly with type 2 diabetes. The sample was taken using a consecutive sampling technique. The intervention given was stretching exercise for 4 weeks. The Wilcoxon Signed Ranks Test statistical test showed that there was a difference between before and after the stretching exercise intervention on the functional status of the elderly, quality of life, general health dimensions, physical health, and social with a p-value (p=0.00), but there is no relationship on the  psychological health and environmental dimension. Based on the results of the study, it can be concluded that stretching exercises can improve physical fitness, muscle mass and joint flexibility which have an impact on functional status and quality of life of the elderly. It is hoped that stretching exercise can be used as one nursing independent treatment to improve the quality of life of and  increasing the independence of the elderly through the provision of education and regular physical exercise. 
Ekspresi Cox-2 Sel Kanker Kolon WiDr Oleh Fraksi n-Heksana Bunga Pepaya Jantan (Carica papaya L.) Yusnita Yusnita
JIFS: JURNAL ILMIAH FARMASI SIMPLISIA Vol. 1 No. 2 (2021): Desember 2021
Publisher : Jurusan Farmasi, Politeknik Kesehatan Kementerian Kesehatan Aceh

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Kanker kolon merupakan salah satu penyebab kematian tertinggi di seluruh dunia. Terdapat lebih dari 1,2 juta kasus tiap tahunnya menempatkan jenis kanker kolon sebagai urutan ketiga yang sering terjadi di dunia maupun di Indonesia. Sehingga dikembangkanlah produk bahan alam yang lebih aman. Namun berkhasiat Salah satu bahan alam yang dapat digunakan sebagai alternatif agent antikanker adalah bunga pepaya jantan (Carica papaya L.). Penelitian ini bertujuan mengetahui aktivitas antikanker fraksi n-heksana bunga pepaya jantan terhadap penekanan ekpresi COX-2 pada sel WiDr secara in Vitro. Pembuatan ekstrak dilakukan dengan cara perkolasi dengan pelarut etanol kemudian di fraksinasi dengan pelarut n-heksana. Fraksi n-heksana bunga pepaya jantan (FnHBPJ) diuji sitotoksiknya terhadap sel WiDr dengan menggunakan metode MTT (3-(4,5-Dimetiltiazol-2-il)-2,5 Difeniltetrazolium Bromida]), uji penekanan ekspresi COX-2 secara imunositokimia. Hasil penelitian menunjukkan bahwa nilai IC50 FnHBPJ pada sel kanker kolon WiDr sebesar 64,105 µg/mL. sehingga mampu menekan ekpresi COX-2