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All Journal Jurnal Penelitian Pendidikan IPA (JPPIPA) Jurnal Agroekoteknologi Terapan COCOS
Adeleyda M. W. Lumingkewas
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education Environmental Science Materials Science & Nanotechnology Physics

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Inggris Adrien Jems Akiles Unitly; Adeleyda M. W. Lumingkewas
Jurnal Penelitian Pendidikan IPA Vol 12 No 5 (2026)
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v12i5.14678

Abstract

This study aims to evaluate the potential of clove syrup as an antioxidant agent to prevent the decrease in the number of Leydig cells and Sertoli cells in a rat model exposed to cigarette smoke. This study used a randomized controlled trial (CRD), where 18 rats were divided into 6 treatment groups with 3 replications, namely K(N): not given treatment, K(-): a group of rats that were given vitamin C then exposed to cigarette smoke 10 cigarettes/day for 14 days, K(+): A group of rats that were exposed to cigarette smoke 10 cigarettes/day for 14 days, and a group of rats that were given clove syrup 1.28ml (P1), clove syrup 2.56ml (P2), clove syrup 3.84ml (P3) then exposed to cigarette smoke 10 cigarettes/day for 14 days. After the rat were treated and necropsied, the testes were taken for HE staining. Leydig cells and Sertoli cells were counted, and the data were analyzed using ANOVA. The results were then further analyzed using the Duncan test (α=0.05) in SAS, followed by the smallest significant difference test. The results of the study showed that clove syrup has antioxidant activity in protecting the number of Leydig cells and Sertoli cells.
Co-Authors Adrien Jems Akiles Unitly Adrien Jems Akiles Unitly Afif Ramadhana Danie Anni E. Tarore Caroulus S. Rante Diane D. Pioh Frangky J. Paat Hendra Yusuf Jimmy Rimbing MARTHA FERA DELLASTRADA GARING Melkison Sanggel Rafli Kawulusan Ricky A. Mangudisang Risky Sekoh Selvie Tumbelaka Selvie Tumbelaka Sofia Wantasen Sriwani Lamasrin Stanley A. F. Walingkas Veronica Ester Buge Youlanda M. Udi