Yuliani Dewi
Universitas Buana Perjuangan Karawang

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Review Artikel: Metode Teknologi Dalam Sistem Penghantaran Obat Transdermal Sediaan Patch Assyfa; Azizah Nurhabibah; Nurul Maulida; Shofia Difa Aulia; Siti Nurcahyati; Yuliani Dewi; Nia Yuniarsih
Jurnal Ilmiah PANNMED (Pharmacist, Analyst, Nurse, Nutrition, Midwivery, Environment, Dentist) Vol. 17 No. 3 (2022): Jurnal Ilmiah PANNMED Periode September- Desember 2022
Publisher : Poltekkes Kemenkes Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (348.178 KB) | DOI: 10.36911/pannmed.v17i3.1487

Abstract

Transdermal is a route of drug administration through the skin, where many lipid layers are difficult to penetrate so that transdermal preparations are needed as a place for drug entry, for example creams and gels. The mechanism of drug delivery is through diffusion of the stratum corneum layer through lipid molecules, before releasing the drug in a controlled and constant manner followed by various other benefits and aims to increase the pharmacological effect in order to reach the maximum level. However, the permeability of the drug is not strong enough to pass through the stratum corneum. So we need a transdermal preparation that can work optimally and overcome the obstacles. This study aims to demonstrate the form, evaluation, formulation, and application of transdermal preparations in new drug delivery systems. Method used literature review of the 10 most journal articles and contains related information. Based on the research results, transdermal dosage forms differ depending on the level of concentration and each technological method needs adapted to the characteristics drug and the route of drug delivery given.
Review Artikel : Pengujian Analisis Metode Kualitatif Terhadap Kandungan Bahan Kimia Obat Pada Jamu Tradisional Shofia Difa Aulia; Salma Aziz; Selviani Eka Suci; Siti Lulu Lutfiah; Yuliani Dewi; Lia Fikayuniar
Jurnal Ilmiah PANNMED (Pharmacist, Analyst, Nurse, Nutrition, Midwivery, Environment, Dentist) Vol. 17 No. 3 (2022): Jurnal Ilmiah PANNMED Periode September- Desember 2022
Publisher : Poltekkes Kemenkes Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (779.698 KB) | DOI: 10.36911/pannmed.v17i3.1491

Abstract

Indonesia is known for its biodiversity of various types, for example, plants, in Indonesia there are around 9000 species of plants that have traditional medicinal properties, 5% as phytopharmaca ingredients, and 1000s of plant species that can be used as herbal medicine. People often manage traditional medicinal herbs with medicinal chemicals so that they are not by the regulations set by the government, this is evidenced by the findings of herbal medicine with medicinal chemicals (BKO).. This review article draws from several national and international research journals released in the period 2012-2022, there are findings of herbal medicine in the Bayuwangi area, Jakarta, Banyumas, Rengel District Market, Pekalongan, Bumiayu, Central Market, Curug District and Probolinggo with herbal findings that have efficacy and chemical content of drugs Glibenclamide (Diabetes Jammu), Sildenafil (Men's Strong Herbal Medicine), Furosemide, Phenolphthalein, Sibutramine (Slimming Herbal Medicine) Dexamethasone, Cyproheftadin (Appetite Enhancement Herb), Theophylline (Shortness of Breathing Herbal Medicine), Paracetamol and Phenylbutason (Jammu) Anti-Pain) was obtained from the Qualitative methods of Thin Layer Chromatography, Spectrophotodesintometry, High Performance Liquid Chromatography, UV-Visible Spectrophotometry, and FTIR