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All Journal Majalah Kedokteran Gigi Indonesia Jurnal Kedokteran Gigi Universitas Padjadjaran Interdental Jurnal Kedokteran Gigi (IJKG)
Eka Pramudita Ramadhany
Departement Gigi Dan Mulut, Fakultas Kedokteran, Universitas Udayana, Denpasar, Bali
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Medicine & Pharmacology Public Health

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GINGIVEKTOMI SEBAGAI TATALAKSANA GINGIVAL ENLARGEMENT PADA PASIEN PERAWATAN ORTHODONTIK CEKAT Ramadhany, Eka Pramudita
Interdental: Jurnal Kedokteran Gigi Vol 15 No 2 (2019): Interdental Jurnal Kedokteran Gigi (IJKG)
Publisher : Faculty of Dentistry, Mahasaraswati Denpasar University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46862/interdental.v15i2.597

Abstract

Gingival enlargement is an increase in gingival size which is a common feature of gingival disease. One of the treatment for gingival is gingivectomy. The purpose of deciding gingivectomy is to remove the gingival tissue which is a pocket wall to enhance visibility and accesbility for self cleaning. A 30 years old female patient presents gingiva that appear enlarged in the lower anterior region. The patient has a history of using fixed orthodontic appliances for 2 years. Gingival enlargement is in the right canine to the left canine. Gingivectomy has performed with conventional techniques using a scalpel. Two weeks control results showed satisfactory results where there was no enlargement of the gingiva. Orthodontic appliances are one of the factors that initiating gingival enlargement. Plaque increased can caused gingival enlargement. Increased pocket depth will cause plaque accumulation and this condition will continue to recur. The diagnosis of enforcement based on etiological decisions is very important in the gingival enlargement treatment requirements.
Effect of sandwich bone augmentation using hydroxyapatite and demineralized freeze- dried bone on infrabony pocket treatment Eka Pramudita Ramadhany; Al Sri Koes Soesilowati; Sri Pramestri Lastianny
Majalah Kedokteran Gigi Indonesia Vol 5, No 3 (2019): December
Publisher : Faculty of Dentistry, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/majkedgiind.37427

Abstract

Periodontitis is periodontal inflammation in response to plaque bacterial antigens, causing damage to periodontal ligament and alveolar bone resorption. Bone graft material combination i.e. demineralized freeze-dried bone allograft (DFDBA) and hydroxyapatite (HA) using sandwich bone augmentation (SBA) method will support each other and will be beneficial to be used as a scaffold. The body takes long time to resorb HA so this could complement DFDBA which is more easily dissolved. This study aimed to reveal the effect of bone graft addition using SBA method on the treatment of infrabony pocket with open flap debridement in terms of probing depth, relative attachment loss, alveolar bone height, and density. This study was carried out to 20 infrabony pockets, where 10 of them were treated using open flap debridement with HA addition, while the other 10 groups were treated using open flap debridement with DFDBA and HA using SBA method. Probing depth  and relative attachment loss were measured on days 0, 30 and 90. Bone height and density were measured using cone-beam computed tomography (images on day 0 and 90). The study showed that probing depth reduction on SBA group was greater than HA group. There were significant differences in probing depth and relative attachment loss examinations. However, bone height and bone density reduction did not show any significant difference. The conclusion from this study is open flap debridement using SBA method yields better regeneration in terms of probing depth and relative attachment loss than open flap debridement with HA addition. There is no difference in bone height and bone density between the two groups.
GINGIVEKTOMI SEBAGAI TATALAKSANA GINGIVAL ENLARGEMENT PADA PASIEN PERAWATAN ORTHODONTIK CEKAT Eka Pramudita Ramadhany
Interdental: Jurnal Kedokteran Gigi Vol. 15 No. 2 (2019): Interdental Jurnal Kedokteran Gigi (IJKG)
Publisher : Faculty of Dentistry, Mahasaraswati Denpasar University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46862/interdental.v15i2.597

Abstract

Gingival enlargement is an increase in gingival size which is a common feature of gingival disease. One of the treatment for gingival is gingivectomy. The purpose of deciding gingivectomy is to remove the gingival tissue which is a pocket wall to enhance visibility and accesbility for self cleaning. A 30 years old female patient presents gingiva that appear enlarged in the lower anterior region. The patient has a history of using fixed orthodontic appliances for 2 years. Gingival enlargement is in the right canine to the left canine. Gingivectomy has performed with conventional techniques using a scalpel. Two weeks control results showed satisfactory results where there was no enlargement of the gingiva. Orthodontic appliances are one of the factors that initiating gingival enlargement. Plaque increased can caused gingival enlargement. Increased pocket depth will cause plaque accumulation and this condition will continue to recur. The diagnosis of enforcement based on etiological decisions is very important in the gingival enlargement treatment requirements.
CHRONIC PERICORONITIS MANAGEMENT WITH OPERCULECTOMY USING SCALPEL: TATALAKSANA PERIKORONITIS KRONIS DENGAN OPERKULEKTOMI MENGGUNAKAN SCALPEL Eka Pramudita Ramadhany; Media Sukmalia Adibah; Putu Fenti Surya; Dwis Syahrul
Interdental Jurnal Kedokteran Gigi (IJKG) Vol. 18 No. 1 (2022): Interdental Jurnal Kedokteran Gigi (IJKG)
Publisher : Fakultas Kedokteran Gigi, Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46862/interdental.v18i1.2965

Abstract

Introduction: Pericoronitis is defined as inflammation of the gingiva caused by infection of the soft tissue around a partially erupted tooth. Pericoronitis is caused by the accumulation of food debris under the operculum surrounding a partially erupted tooth, which provides a place for a wide variety of polymicrobial flora. The most common area for pericoronitis is the partially erupted lower third molar. According to the international classification, pericoronitis can be classified as acute and chronic. Case: A 23-year-old female patient came with complaints of pain in the lower left side. Clinical and radiographic examination showed 38 partially erupted teeth with vertical grade 1 A impaction. The operator decided to perform operculectomy on tooth 38. Case Treatment: The procedure was carried out under infiltration anesthesia with lidocaine HCl + epinephrine, the incision was made using a blade no.12 on the bleeding point that had been made previously, after excision of the operculum, the operating area was irrigated with saline solution and controlled bleeding with the application of a periodontal pack. Discussions: After one week of control, there was still redness and pain when palpated, then oxyfresh gel was applied. four week follow up shows, there was no redness, and pain when palpated. Wound healing after operculectomy looks good, no reccurent and inflammation sign and the patient has no complaints Conclusion and Suggestions: Operculectomy can be the main therapy in cases of pericoronitis with vertical IA and partial eruption.
Effect of 4% and 15% moringa leaf extract gel on gingival wound healing in rats Ramadhany, Eka Pramudita; Ambarawati, I Gusti Agung Dyah; Musyaffa, Muhammad Rafif
Majalah Kedokteran Gigi Indonesia Vol 8, No 3 (2022): December
Publisher : Faculty of Dentistry, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/majkedgiind.76416

Abstract

Traumatic dental procedures such as incisions and gingival flaps are the leading causes of injury to the gingival structure. One of natural ingredients that can potentially accelerate the wound healing process is Moringa leaves Moringa oleifera). Moringa leaf has several active compounds, one of which is flavonoids, which can be an antiinflammatory and antibacterial agent, and increase collagen synthesis. A randomized posttest-only control-group design was used in this study. 48 wistar rats were categorized into four groups: CMC-Na gel, hyaluronic acid, 4% Moringa leaf extract gel, and 15% Moringa leaf extract gel. The samples were then euthanized on days 1, 3, 5, and 7. The two-way ANOVA test described significant differences (p < 0.05) for all the components of the observation (neutrophils, fibroblasts, angiogenesis, and epithelial thickness). The lowest mean number of neutrophils, the highest mean number of fibroblasts, and the highest mean of angiogenesis were found in the 15% Moringa extract group on the 7th day. The highest mean epithelial thickness was found in the use of 4% Moringa extract on the 5thday. The microscopic images showed that the treatment group gained more effective wound healing processes than the control group. The microscopic image showed that, in terms of neutrophils, fibroblasts, and angiogenesis, 15% Moringa extract was more effective for wound healing compared to 4% Moringa extract.
Differences in The Effects Of 15% Moringa Leaf (Moringa oleifera) Extract Gel and 70% Kecemcem (Spondias pinnata) Tree Bark Extract Gel on The Number of Gingiva Fibroblasts In Wistar Rats Postcurettage With Periodontitis Conditions Ramadhany, Eka Pramudita; Susilahati, Ni Luh Desy Ayu; Dewi, Ni Putu Vania Amelia
Interdental Jurnal Kedokteran Gigi (IJKG) Vol. 21 No. 2 (2025): Interdental Jurnal Kedokteran Gigi (IJKG)
Publisher : Fakultas Kedokteran Gigi, Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46862/interdental.v21i2.11775

Abstract

Introduction: Periodontitis is a prevalent global oral disease leading to increased dental tourism, including to Indonesia. One treatment for periodontitis is gingival curettage with adjuvant therapy to speed up wound healing. Studies suggest that moringa leaf extract and kecemcem tree bark contain active compounds with anti-inflammatory and antioxidant properties. This study compares the effects of 15% moringa leaf extract gel and 70% kecemcem tree bark extract gel on the number of gingival fibroblasts in Wistar rats after curettage under periodontitis conditions. Material and Methods: Wistar rats were divided into four groups: positive control (hyaluronic acid), negative control (CMC-Na), 15% moringa leaf treatment, and 70% kecemcem tree bark treatment. Periodontitis was induced by tying a silk thread to the mandibular side, followed by curettage with a Sub-Zero (Osung) curette. The rats were euthanized on days 3, 5, and 7. Histological preparations were made, and fibroblast counts were taken from three fields of view using a light microscope at 400x magnification. Results and Discussion: The average number of fibroblasts in the kecemcem tree bark treatment group was higher than in the moringa leaf treatment group. The Least Significant Difference Post Hoc test showed a significant difference (p < 0.05). Flavonoids, phenols, and β-sitosterol in kecemcem tree bark were more effective in increasing fibroblast numbers compared to moringa leaf extract, as indicated by the higher average fibroblast count. Conclusion: 70% kecemcem tree bark extract gel had a more significant effect than 15% moringa leaf extract gel in increasing gingival fibroblasts in Wistar rats after curettage with periodontitis.
Perbedaan efek pemberian gel kombinasi ekstrak Camellia sinensis dan kitosan terhadap jumlah sel neutrofil pasca ekstraksi gigi tikus Wistar: eksperimental laboratoris Anggayanti, Nyoman Ayu; Ramadhany, Eka Pramudita; Putu Diah Suryani, I Gusti Ayu
Jurnal Kedokteran Gigi Universitas Padjadjaran Vol 37, No 1 (2025): April 2025
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/jkg.v37i1.59224

Abstract

Pendahuluan: Neutrofil berperan penting dalam mengatur peradangan selama penyembuhan luka. Camellia sinensis (teh hijau) terbukti mengandung Epigallocatechin Gallate (EGCG) yang memiliki aktivitas anti inflamasi. Kitosan dengan kemampuannya menjaga stabilitas EGCG, berpotensi untuk meningkatkan efektivitas EGCG dalam mengurangi inflamasi. Penelitian ini bertujuan untuk menganalisis perbedaan efek pemberian gel ekstrak Camellia sinensis yang dikombinasikan dengan kitosan terhadap jumlah neutrofil sebagai indikator utama fase inflamasi pada tikus Wistar pasca ekstraksi gigi. Metode: Gigi insisivus mandibula kiri pada tikus diekstraksi setelah dilakukan anestesi. Soket pada kelompok perlakuan diberi gel kombinasi ekstrak Camellia sinensis dan kitosan, sedangkan kelompok kontrol tidak diberikan intervensi. Pemeriksaan histopatologi soket dilakukan untuk menilai keberadaan neutrofil pada hari pertama, ketiga, kelima, dan ketujuh pasca perlakuan. Data yang diperoleh dianalisis menggunakan uji Kruskal-Wallis dan Mann-Whitney berdasarkan karakteristik distribusi. Hasil: Jumlah neutrofil pada kelompok perlakuan mengalami penurunan yang signifikan disetiap hari pengamatan dibandingkan kelompok kontrol yang menunjukan proses penyembuhan yang lebih baik dengan tidak adanya inflamasi persisten (p=0.000, p<0.05). Simpulan: Kombinasi ekstrak Camellia sinensis dan kitosan berefek terhadap penurunan jumlah neutrofil pasca ekstraksi gigi tikus Wistar.The effect of gel Camellia sinensis extract in combination with chitosan on neutrophils count of Wistar rats after tooth extraction: A Laboratory Experimental StudyIntroduction: Neutrophils play a key role in regulating inflammation during wound healing. Camellia sinensis has been proven to contain Epigallocatechin Gallate (EGCG), which exhibits anti-inflammatory activity. Chitosan with its ability to maintain EGCG stability, offers the potential to enhance the effectiveness of EGCG in reducing inflammation. This research aims to analyze the effect of extract gel Camellia sinensis combined with chitosan on the number of neutrophils as the main indicator of the inflammatory phase in Wistar rats after tooth extraction. Methods: The left mandibular incisor was extracted after the rats were anesthetized. The socket in the treatment group was treated with gel combining Camellia sinensis extract and chitosan, while the control group did receive any intervention. A histopathological examination of the socket was conducted to assess the presence of neutrophil on days one, three, five, and seven after treatment. The obtained data were analyzed using Kruskal-Wallis and Mann-Whitney tests based on the distribution characteristics. Results: The number of neutrophils in the treatment group decreased significantly on each day of observation compared to the control group, indicating a more advanced healing process with the absence of persistent inflammation (p=0.000, p<0.05). Conclusion: The combination of Camellia sinensis extract and chitosan had an effect on reducing the number of neutrophils in Wistar rats after tooth extraction.
Co-Authors Al Sri Koes Soesilowati Ambarawati, I Gusti Agung Dyah Dewi, Ni Putu Vania Amelia Media Sukmalia Adibah Musyaffa, Muhammad Rafif Nyoman Ayu Anggayanti Putu Diah Suryani, I Gusti Ayu Putu Fenti Surya Sri Pramestri Lastianny, Sri Pramestri Susilahati, Ni Luh Desy Ayu Syahrul, Dwis