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Dwiki WIjaya Rahman
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Education Health Professions Medicine & Pharmacology Neuroscience Public Health

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Diagnosis dan Tatalaksana HIV grade III dengan TB paru Benny Syahputra Gumay; Dwiki WIjaya Rahman; Risti Graharti
Medula Vol 13 No 1 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i1.607

Abstract

Human immunodeficiency virus (HIV) is an infection that attacks the immune system, specifically white blood cells called CD4+ cells. HIV continues to be a major global public health problem, claiming 40.1 million lives so far. By 2021, 650,000 people will die from HIV-related causes and 1.5 million people will contract HIV. HIV destroys CD4+ cells, thereby overcoming a person's immunity against opportunistic infections, such as tuberculosis, yeast infections, bacterial infections, and some cancers. Case report of a 29 year old man, came with complaints of shortness of breath since 3 days before entering the hospital. Complaints are accompanied by a long cough, weakness, cold sweats at night, loss of appetite, and weight loss. The serological examination showed HIV reactive results and the chest X-ray showed the impression of active pulmonary TB. The diagnosis established was HIV grade III with clinically diagnosed pulmonary TB, after which the patient was given HIV treatment with co-infected pulmonary TB.
Peningkatan Risiko infeksi Multi Drugs Resitant Tuberculosis (MDR-TB) pada Penderita Human Immunodeficiency Virus (HIV) Dwiki Wijaya Rahman; Ety Apriliana
MAJORITY Vol 9 No 2 (2020): MAJORITY
Publisher : Majority

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Abstract

HIV infection is the biggest challenge for tuberculosis control efforts. People with HIV will have a greater potential to be infected with tuberculosis as an opportunistic disease or to aggravate existing tuberculosis into active tuberculosis. MDR-TB is tuberculosis that is resistant to at least 2 types of anti-tuberculosis drugs (OAT). HIV sufferers will be more at risk of experiencing MDR-TB coinfection due to several reasons, one of which is HIV infection which can cause OAT malabsorption, such as rifampin and ethambutol, too much treatment causes patient non-compliance with treatment, and the possibility of HIV and MDR-TB sufferers who are in areas of the same prevalence, such as in hospitals and densely populated environments, cause the transmission of MDR-TB is more susceptible to HIV sufferers due to a weakened immune system.
Co-Authors Benny Syahputra Gumay Ety Apriliana Risti Graharti