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All Journal CURRENT INTERNAL MEDICINE RESEARCH AND PRACTICE SURABAYA JOURNAL International Journal of Medicine and Health
Marsha Zahrani
Universitas Airlangga
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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The Frequency of Multidrug-Resistant Tuberculosis Patient who have History of Tuberculosis, HIV, and Diabetes Mellitus at Dr. Soetomo General Academic Hospital Marsha Zahrani; Rebekah J. Setiabudi; Helmia Hasan; Manik Retno Wahyunitisari
Current Internal Medicine Research and Practice Surabaya Journal Vol. 4 No. 1 (2023): CURRENT INTERNAL MEDICINE RESEARCH AND PRACTICE SURABAYA JOURNAL
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/cimrj.v4i1.42603

Abstract

Introduction: The main causes of MDR TB include interperson transmission and TB treatment failure. In addition to TB, HIV and diabetes mellitus may raise the risk of TB MDR. To determine the TB MDR risk factors, it's critical to understand the prevalence of TB MDR patients with TB, HIV, and diabetes mellitus histories.Methods: This study is an observational descriptive study with a retrospective design. The sample for this study was all patients from the TB and MDR-TB polyclinic at Dr. Soetomo General Academic Hospital, Surabaya, in January 2020–December 2020 who met the inclusion criteria. The data obtained were analyzed descriptively.Results: There were 72 patients who met the criteria: there were 26 patients who have a history of TB, 15 patients who only have a history of diabetes mellitus, 2 patients who only have a history of HIV, 27 patients who have a history of TB with diabetes mellitus, and 2 patients who have a history of TB with HIV.Conclusion: The data could support the theory of an association between MDR-TB with TB, HIV, and diabetes mellitus and increase the awareness of primary MDR TB cases with history of HIV and diabetes mellitus.
Association Between Ultra-Processed Food Consumption and Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) in Adults: A Systematic Review Lila Amila; Kurnia Agustina Sitompul; Maretha Primariayu; Dalilah Salsabila Salma; Siti Aria Rahmani Novianto; Marsha Zahrani; Nadia Mardiana Hudan
International Journal of Medicine and Health Vol. 5 No. 3 (2026): September: International Journal of Medicine and Health
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/ijmh.v5i3.6394

Abstract

Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most common chronic liver disease globally, but its association with ultra-processed food (UPF) consumption under the new diagnostic framework has not been systematically synthesized. We systematically searched PubMed/MEDLINE, Embase, Cochrane CENTRAL, Scopus, and Web of Science for observational studies examining habitual UPF intake (NOVA classification) and MASLD/NAFLD in general adult populations using validated outcome ascertainment. Quality was appraised via the Newcastle-Ottawa Scale (NOS) and certainty via GRADE. Eight studies comprising >350,000 adults across six countries met the eligibility criteria, with seven rated as good methodological quality. All eight studies reported a positive association between higher UPF consumption and MASLD risk, with prospective adjusted hazard ratios ranging from 1.18 to 1.50 and cross-sectional odds ratios from 1.33 to 2.50. Additionally, decreasing UPF intake significantly lowered intrahepatic fat (7.7% to 2.6%), and an exposure-response gradient was observed across several cohorts. Approximately two-thirds of the association was mediated by adiposity (attenuated after BMI adjustment), while evidence for hepatic fibrosis remained inconsistent. GRADE certainty was rated as Low for the primary association and exposure-response gradient, and Very Low for intrahepatic fat and fibrosis outcomes. In conclusion, higher habitual UPF intake is consistently associated with an increased burden of MASLD in adults, largely mediated by adiposity. Although observational nature limits direct causality, these findings support restricting UPF consumption while awaiting further prospective studies using explicit MASLD criteria.
Co-Authors Dalilah Salsabila Salma Hasan, Helmia Kurnia Agustina Sitompul Lila Amila ManikRetno Wahyunitisari Maretha Primariayu Nadia Mardiana Hudan Rebekah Setiabudi, Rebekah Siti Aria Rahmani Novianto