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All Journal Media Farmasi Indonesia Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Muhammad Akib Yuswar
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Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology Nursing Public Health Other

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The Relationship Between The Rationality Of Prescribing And The Quality Of Life Of Hypertension Patients At The Central Siantan Health Center In Pontianak Muhammad Akib Yuswar
Media Farmasi Indonesia Vol. 19 No. 1 (2024): Media Farmasi Indonesia
Publisher : SEKOLAH TINGGI ILMU FARMASI YAYASAN PHARMASI SEMARANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53359/mfi.v19i1.251

Abstract

Hypertension is a silent killer disease that can affect the patient's quality of life. There is a need for rational treatment to achieve the success of therapy and the desired quality of life. This study aims to determine the relationship between the rationality of prescribing and the quality of life of hypertensive patients. The study design was an observational cohort. Data were obtained from hypertensive patients at the Puskesmas Siantan Tengah Pontianak who met the inclusion criteria in June-July 2021 using a prospective purposive sampling and collected from medical records, EQ5D5L and VAS questionnaires. The results of the study on 101 samples were obtained; the rationality of prescribing antihypertensive drugs was rational, with the percentage of rationality being the appropriate indication 87,12%; appropriate drug 87.12%; appropriate patient 88.11%; and appropriate dose 88.11%. In addition, 28 patients (27.72%) did not have a problem with the five dimensions with the highest EQ5D5L index of 1,000, while the quality of life, as measured by VAS, had a median value of 60. The results of the Pearson chi-square test showed that there was a relationship between the rationality of prescription and quality of life for hypertensive patients with a significance value ≥ 0.05 using the EQ5D5L (p = 0.688) and VAS (p = 0.583) questionnaires. Conclusion: there is no significant relationship between the rationality of prescribing and the quality of life of hypertensive patients, both using the EQ5D5L and VAS questionnaires.
IDENTIFIKASI DAMPAK INTERAKSI OBAT ANTIHIPERTENSI TERHADAP TEKANAN DARAH PADA PASIEN GERIATRI HIPERTENSI YANG DIRAWAT INAP DI RSUD DR SOEDARSO PONTIANAK Muhammad Akib Yuswar; Egida Rachmadani; Eka Kartika Untari
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 8 No. 1 (2022): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v8i1.524

Abstract

Hypertension is one of cardiovascular diseases in geriatrics. Hypertensive geriatric patients require a combination of more antihypertensives to achieve blood pressure targets, it can cause high risk of polypharmacy. Polypharmacy in hypertensive geriatric patients is at high risk of drug interactions that can affect their blood pressure. This study aims to identify the interactions of antihypertensives based on mechanism and severity and also to determine whether there is a change in blood pressure caused by drug interactions in geriatric hypertensive inpatients at RSUD Dr Soedarso on January – June 2019. Data were collected retrospectively from 38 patients’ medical records, using total sampling technique. Data were analyzed descriptively using E-book Stockley’s Drug Interaction and Drug Interaction Checker on medscape.com, drugs.com. There were 28 patients (73%) who may experience drug interactions with a total of 85 cases. Drug interactions with moderate severity and pharmacodynamic interaction mechanism often occur in a row were 61 cases (72%) and 79 cases (93%). There were a decrease and increase blood pressure, which in a row were 23 and 4 patients. The decrease of patients’ blood pressure estimated caused by synergistic drug interactions of antihypertensives and adjustment of each drug dose that has potential to increase blood pressure.
Co-Authors Egida Rachmadani Eka Kartika Untari Nera Umilia Purwanti Umi Khairiyah