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Gambaran Rasionalitas Penggunaan Obat Antihipertensi pada Pasien Hipertensi di Instalasi Rawat Jalan RSUD Sultan Syarif Mohamad Alkadrie Pontianak Tahun 2020 Muhammad Akib Yuswar; Nera Umilia Purwanti; Umi Khairiyah
Jurnal Pharmascience Vol 10, No 1 (2023): Jurnal Pharmascience
Publisher : Program Studi Farmasi FMIPA Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v10i1.14041

Abstract

Hipertensi adalah keadaan peningkatan tekanan darah di atas ambang batas normal yaitu 120/80 mmHg. Penggunaan obat yang rasional merupakan langkah untuk mendapatkan pelayanan kesehatan yang baik. Tujuan dari penelitian ini adalah menggambarkan rasionalitas dan distribusi pola penggunaan obat pada pasien hipertensi tanpa dan dengan penyakit penyerta di instalasi rawat jalan RSUD Sultan Syarif Mohamad Alkadrie Pontianak berdasarkan kriteria tepat indikasi, tepat obat, tepat dosis, dan tepat pasien. Metode yang digunakan adalah metode observasional deskriptif dengan rancangan cross sectional. Pengumpulan data dilakukan secara retrospektif melalui penelusuran data rekam medis dan data resep pasien periode Januari- Desember 2020. Hasil penelitian menunjukkan bahwa pasien hipertensi paling banyak berusia 56-65 tahun (41,24%), jenis kelamin terbanyak yaitu perempuan (51,55%), tekanan darah paling banyak yang diderita adalah hipertensi stage 2 (63,23%) dan pasien hipertensi paling banyak menderita hipertensi dengan penyakit penyerta (75,74%). Hasil analisis rasionalitas penggunaan obat antihipertensi pada pasien hipertensi tanpa penyakit penyerta berdasarkan tepat indikasi sebanyak 93,94%, tepat obat sebanyak 72,73%, tepat dosis sebanyak 100%, serta tepat pasien sebanyak 100% dan dengan penyakit penyerta berdasarkan tepat indikasi sebanyak 100%, tepat obat sebanyak 80,58%, tepat dosis sebanyak 100%, dan tepat pasien sebanyak 42,72%. Distribusi pola penggunaan obat antihipertensi yang paling sering digunakan dalam pengobatan hipertensi adalah amlodipin. Kata Kunci: Hipertensi, Amlodipin, Evaluasi, Penyakit Penyerta, Pola Penggunaan Hypertension is a condition where there is an increase in blood pressure above the normal threshold of 120/80 mmHg. Rational use of drugs is a step to get good health services. The purpose of this study was to describe the rationality and distribution of drug use patterns in hypertensive patients without and with comorbidities in the outpatient installation of RSUD Sultan Syarif Mohamad Alkadrie in Pontianak based on the criteria for the right indication, the right drug, the right dose, and the right patient. The method used is descriptive observational method with a cross sectional design. Data collection was carried out retrospectively through searching medical record data and patient prescription data for the period January-December 2020. The results showed that the majority of hypertensive patients were aged 56-65 years (41.24%), the most gender was female (51.55%), the highest blood pressure suffered was stage 2 hypertension (63.23%) and hypertension patients suffered the most from hypertension with comorbidities (75.74%). The results show the rationality of the use of antihypertensive drugs in hypertensive patients without comorbidities based on the right indication by 93.94%, the right drug by 72.73%, the right dose by 100%, and the right patient by 100% and with comorbidities based on the right indication by 100%, the right drug by 80.58%, the right dose by 100%, and the right patient by 42.72%. The distribution of the pattern of use of the most commonly used antihypertensive drug  is amlodipine.
The Relationship Between The Rationality Of Prescribing And The Quality Of Life Of Hypertension Patients At The Central Siantan Health Center In Pontianak Muhammad Akib Yuswar
Media Farmasi Indonesia Vol. 19 No. 1 (2024): Media Farmasi Indonesia
Publisher : SEKOLAH TINGGI ILMU FARMASI YAYASAN PHARMASI SEMARANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53359/mfi.v19i1.251

Abstract

Hypertension is a silent killer disease that can affect the patient's quality of life. There is a need for rational treatment to achieve the success of therapy and the desired quality of life. This study aims to determine the relationship between the rationality of prescribing and the quality of life of hypertensive patients. The study design was an observational cohort. Data were obtained from hypertensive patients at the Puskesmas Siantan Tengah Pontianak who met the inclusion criteria in June-July 2021 using a prospective purposive sampling and collected from medical records, EQ5D5L and VAS questionnaires. The results of the study on 101 samples were obtained; the rationality of prescribing antihypertensive drugs was rational, with the percentage of rationality being the appropriate indication 87,12%; appropriate drug 87.12%; appropriate patient 88.11%; and appropriate dose 88.11%. In addition, 28 patients (27.72%) did not have a problem with the five dimensions with the highest EQ5D5L index of 1,000, while the quality of life, as measured by VAS, had a median value of 60. The results of the Pearson chi-square test showed that there was a relationship between the rationality of prescription and quality of life for hypertensive patients with a significance value ≥ 0.05 using the EQ5D5L (p = 0.688) and VAS (p = 0.583) questionnaires. Conclusion: there is no significant relationship between the rationality of prescribing and the quality of life of hypertensive patients, both using the EQ5D5L and VAS questionnaires.
IDENTIFIKASI DAMPAK INTERAKSI OBAT ANTIHIPERTENSI TERHADAP TEKANAN DARAH PADA PASIEN GERIATRI HIPERTENSI YANG DIRAWAT INAP DI RSUD DR SOEDARSO PONTIANAK Muhammad Akib Yuswar; Egida Rachmadani; Eka Kartika Untari
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 8 No. 1 (2022): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v8i1.524

Abstract

Hypertension is one of cardiovascular diseases in geriatrics. Hypertensive geriatric patients require a combination of more antihypertensives to achieve blood pressure targets, it can cause high risk of polypharmacy. Polypharmacy in hypertensive geriatric patients is at high risk of drug interactions that can affect their blood pressure. This study aims to identify the interactions of antihypertensives based on mechanism and severity and also to determine whether there is a change in blood pressure caused by drug interactions in geriatric hypertensive inpatients at RSUD Dr Soedarso on January – June 2019. Data were collected retrospectively from 38 patients’ medical records, using total sampling technique. Data were analyzed descriptively using E-book Stockley’s Drug Interaction and Drug Interaction Checker on medscape.com, drugs.com. There were 28 patients (73%) who may experience drug interactions with a total of 85 cases. Drug interactions with moderate severity and pharmacodynamic interaction mechanism often occur in a row were 61 cases (72%) and 79 cases (93%). There were a decrease and increase blood pressure, which in a row were 23 and 4 patients. The decrease of patients’ blood pressure estimated caused by synergistic drug interactions of antihypertensives and adjustment of each drug dose that has potential to increase blood pressure.