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Karakteristik penderita Gangguan Kecemasan Menyeluruh Pada Grave’s Disease dengan gambaran EKG Sick Sinus Syndrome (SSS) R. Mohamad Javier; Andisa Fadhila Rialdi; Syarif Syamsi Ahyandi; Ericko Julian Limanto; Ehwanul Handika; Badrul Munir; Pertiwi Febriana Chandrawati; Andi Abdillah; Maisuri T. Chalid; Himawan Wicaksono; A. Rusli Budi Ansyah; I Nyoman Mudana
Syntax Idea 137-156
Publisher : Ridwan Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/syntax-idea.v5i2.2135

Abstract

Sekitar 60%-80% kasus hipertiroidisme diakibatkan oleh Graves’ disease dimana wanita pada usia 20-50th lebih dominan dibandingkan laki-laki. Graves’ disease adalah suatu kelainan autoimun, adanya thyroid stimulating immunoglobulin (TSI), atau bisa disebut dengan thyroid stimulating antibody (TSAb) yang disekresikan di kelenjar tiroid berikatan dengan reseptor thyroid stimulating hormone (TSH) di kelenjar tiroid. Sehingga merangsang kelenjar tiroid untuk bekerja memproduksi hormon tiroksin berdasarkan rangsangan dari reseptor TSH. Rangsangan terus menerus dari TSAb mengakibatkan keadaan hipertiroidisme dan tiromegaly. Keadaan hipertiroidisme menyebabkan denyut jantung melemah dan gambaran pola EKG yang menunjukkan sindrom sinus sakit termasuk bradikardia sinus (denyut jantung <40 bpm), jeda sinus (jeda tiba-tiba nodus sinus lebih pendek dari 2-3 detik), dan henti sinus. Tujuan, Mengetahui karakteristik penderita gangguan kecemasan menyeluruh pada graves disease dengan gambaran EKG sick sinus syndrome (SSS). Metode, Penelitian ini merupakan Systematic Review dengan menggunakan metode Preferred Reporting Items for Systematic Reviews and Meta-analyses atau biasa disebut PRISMA, metode ini dilakukan secara sistematis dengan mengikuti tahapan atau protokol penelitian yang benar. Sumber diambil dari situs PubMed dan situs Google Scholar dengan jurnal terbitan tahun 2017-2022 lalu dilakukan screening didapatkan hasil 15.486. Hasil, Dilakukan klasterisasi jurnal dan didapatkan jumlah jurnal terindex scopus Q1 sejumlah 2 jurnal, Q2 2 jurnal, terindeks Sinta S1 1 jurnal, sehingga terdapat 5 jurnal yang diekstraksi. Kesimpulan, Mayoritas jurnal membahas mengenai usia dan gaya hidup yang berkaitan dengan karakteristik terjadinya grave disease serta faktor risiko grave disease ditentukan berdasarkan usia serta grave disease berhubungan dengan gangguan kecemasan, gambaran EKG sick sinus syndrome (SSS).
Effect of Snakebite on Osteomyelitis and Cardiac Shock in Pediatric and Adult Patients R. Mohamad Javier; Laksmitha Saktiono Safitri; Andisa Fadhila Rialdi; Ehwanul Handika; Ericko Julian Limanto; Budi Prakoso; Bambang Widiwanto; Himawan Wicaksono; Zainuddin Hamidi; Djanuar Fitriadi; Sukirman Sukirman
Journal of Social Research Vol. 2 No. 4 (2023): Journal of Social Research
Publisher : International Journal Labs

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55324/josr.v2i4.778

Abstract

Snakebite is a defense mechanism of snakes and can be a medical emergency. Snake venom contains a mixture of protein components that affect the functional activity of the target physiology. The structure of the poison in snake venom has different variations for different snake species. As for snakebite, it can be life-threatening if it has neurotoxic, cytotoxic, or hemotoxic toxic effects. The purpose of this study is to determine the relationship between snakebite incidence to osteomyelitis and cardiogenic shock. The results of this study can be used as a source of information and an objective correlation reference regarding the relationship between snakebite and osteomyelitis and cardiogenic shock. This research is a Systematic Review using the Preferred Reporting Items for Systematic Reviews and Meta-analyses method or commonly called PRISMA, this method is carried out systematically by following the correct research stages or protocols. Antivenom neutralizes toxins in fixed quantities. Both children and adults are given the same amount of antivenom because snakes inject the same amount of poison into both adults and children. Antivenom can be effective as long as the poison is still active in the patient's body causing symptoms of systemic intoxication. It can last for several days or even weeks after the bite. After a series of processes have been passed, based on the results of research in the Scopus-indexed journal on the systematic "The Relationship of Snakebite with Osteomyelitis and Cardiac shock in Pediatric and Adult Patients" a conclusion can be drawn, namely that the majority of journals discuss heart disorders and infections, necrosis of muscles and bones related to poisonous snake bites.
Pengaruh Kejadian Tetralogy of Fallot pada Anak dengan Riwayat Diabetes Mellitus Tipe II dengan Labiopalatochiszis Afif Ferdian; R. Mohamad Javier; Himawan Wicaksono; Budi Prakoso; Ananingati Ananingati; Akhmad Rusli Budi Ansyah
Syntax Idea 508-524
Publisher : Ridwan Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/syntax-idea.v5i5.2189

Abstract

There is a suspicion that the condition of the cleft lip and palate has something to do with labiopalatochiszis with COL1A2 heterozygous mutations and DNA formation accompanied by Tetralogy of Fallot in children and history of type II diabetes mellitus in mothers. Then, it is also found in infants with labiopalatochiszis usually accompanied by frequent occurrences of TOF due to the genetic influence of the event. This has led to speculation that there are links between the above variables and cleft lip and palate. Therefore, this study tries to find the relationship between these variables. Objective: Determine the effect of tetralogy of fallot events on children with a history of type II diabetes mellitus and Labiopalatochiszis. This research is a Systematic Review using the Preferred Reporting Items for Systematic Reviews and Meta-analyses method or commonly called PRISMA, this method is carried out systematically by following the correct research stages or protocols. Sources taken from the Google Scholar site with journals published in 2017-2023 and then screened 1,870 journals. Journal clustering was carried out and obtained the number of journals indexed Q1 amounting to 4 journals, Q3 amounting to 1 journal, and Q4 amounting to 1 journal so that there were 6 journals extracted. The entire journal does not discuss directly the relationship between research variables, but only provides an overview of the influence that TOF occurs on mothers with type 2 diabetes mellitus conditions and the occurrence of labiopalatochiszis.