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All Journal Sriwijaya Journal of Dentistry
Siti Rusdiana Puspa Dewi
Dentistry Program, Faculty of Medicine, Sriwijaya University, Palembang, Indonesia
Dentistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Public Health

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Acute Pseudomembran Candidiasis In A Patient With Osteogenic Sarcoma And Anemia Zara Alviometha; Ade Puspa Sari; Siti Rusdiana Puspa Dewi
Sriwijaya Journal of Dentistry Vol. 2 No. 1 (2021): Sriwijaya Journal of Dentistry
Publisher : Dentistry Study Program, Faculty of Medicine Universitas Sriwijaya 

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (272.341 KB) | DOI: 10.32539/sjd.v2i1.588

Abstract

Introduction: Acute pseudomembranous candidiasis is an opportunistic infection caused by the overgrowth of Candida spp. Candida spp can become pathogenic in a weak immune response. There is a clear relationship between oral candidiasis and patients with malignant disease (cancer) and hematological disorders, such as anemia. Anemia is a complication that often occurs in patients with malignancy. Purpose: This paper reports a case of acute pseudomembtane candidasis caused by osteogenic sarcoma and secondary anemia. Case presentation: A 12-year-old male patient was hospitalized for osteogenic sarcoma and anemia. Intraoral examination showed white plaque that could be wiped out on the tongue dorsum. Candida albicans was identified by oral microbial tests. Antifungal therapy was applied for 14 days and it showed improvement. Conclusion: The successful management of this patient involves control of predisposing factors, plaque control, and DHE.
The Effect of Antibacterial Agent of Pangasius sutchi Bone Extract Against Porphyromonas gingivalis Muhammad Rizky Pratama; Siti Rusdiana Puspa Dewi; Hema Awalia
Sriwijaya Journal of Dentistry Vol. 4 No. 1 (2023): Sriwijaya Journal of Dentistry
Publisher : Dentistry Study Program, Faculty of Medicine Universitas Sriwijaya 

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/sjd.v4i1.39

Abstract

Introduction: Periodontal disease is the most common dental problem mainly due to bacterial infection. The highest virulence bacteria found in periodontal disease is Porphyromonas gingivalis. Pangasius sutchi bone extract contains bioactive peptides which have the potential effect to inhibit the growth of Gram-negative bacteria such as P. gingivalis. Purpose: This study aimed to determine the effect of an antibacterial agent of Pangasius sutchi bone extract against Porphyromonas gingivalis. Methods: This research was in vitro laboratory experimental study with a post-test-only control group design. The treatment groups consisted of Pangasius sutchi bone extract using concentrations of 10%, 20%, 40%, 60%, and 100%, positive control (cefixime) and negative control (placebo). Results: The results showed that each concentration of Pangasius sutchi bone extract had antibacterial properties. The largest diameter of the inhibitory zone was at 100% concentration. The minimum Bactericidal Concentration (MBC) was at a concentration of 40%, and the Minimum Inhibitory Concentration (MIC) was 20%. Conclusion: Pangasius sutchi bone extract had an antibacterial effect against Porphyromonas gingivalis.
Co-Authors Ade Puspa Sari Hema Awalia Muhammad Rizky Pratama Zara Alviometha