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All Journal Aesculapius Medical Journal Journal of Global Pharma Technology
Ni Kadek Elmy Saniathi
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Education Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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The Association between Plasma Soluble ICAM-1 and Adiponectin with Over Nutrition in Pediatric Patients with Dengue Infection Ni Kadek Elmy Saniathi
Journal of Global Pharma Technology Volume 11 Issue 04.
Publisher : Journal of Global Pharma Technology

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Abstract

Introduction: Dengue Hemorrhagic Fever (DHF) is one of the urgent health problems in tropical countries, including Indonesia. On the other hand, the prevalence of overweight is also increasing among children even in developing countries. Recent studies proved that adiponectin has significant influence toward immune system. Therefore, this study aimed to provide a preliminary data about the relationship between overweight and DHF with sICAM-1 as the biomarker. Method: An analytic observational study with nested case control study design was conducted using 78 subjects. The DHF status was established using 1997 WHO criteria while the sICAM-1 and Adiponectin were assessed using ELISA technique. All of the data were statistically analyzed. Result: The baseline characteristics of the subjects between the groups were considered homogenous. The Odds ratio of overweight toward the risk of dengue shock syndrome (DSS) was found to be quite high at 2.89 (95% CI: 0.81 – 12.25) while the adiponectin level was also significantly different between overweight and normal subjects in DHF group. However, no significant difference was found in sICAM-1 level between the groups. Conclusion: It can be concluded that sICAM-1 and adiponectin level was differ between patient with over-nutrition than normal counterparts with over-nutritional patients tended to have higher sICAM-1 and lower adiponectin level. But the difference was not statistically significant.Keywords: Dengue hemorrhagic fever, Overweight, sICAM-1, Dengue shock syndrome.
Hubungan Aktivitas Fisik dan Pola Makan dengan Status Gizi pada Anak Sekolah Dasar Usia 9-13 Tahun di Sekolah Dasar Negeri 12 Dauh Puri Komang Permata Indah Sari; Ni Kadek Elmy Saniathi; Dewa Ayu Agung Alit Suka Astini
Aesculapius Medical Journal Vol 4 No 1 (2024): February
Publisher : Fakultas Ilmu Kedokteran dan Ilmu Kesehatan, Universitas Warmadewa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/amj.4.1.2024.69-74

Abstract

Indonesia kini dihadapkan pada dua permasalahan gizi, yaitu gizi kurang serta penyakit menular yang tak mampu teratasi dengan keseluruhan hingga saat ini. Kekurangan gizi akan mempengaruhi aktivitas yang diakibatkan oleh malnutrisi dan pola makan yang buruk. Penelitian bertujuan mencari tau korelasi antara aktivitas fisik serta pola makan pada status gizi anak yang sedang menempuh sekolah dasar umur 9-13 tahun pada SDN 12 Dauh Puri. Penelitian mempergunakan metode analitik kuantitatif , pendekatan cross-sectional dengan pencatatan antropometri dan pengumpulan survei melalui kuesioner. Responden penelitian berjumlah 87 orang memenuhi syarat inklusi penelitian. Data kemudian diuji korelasi dengan Rank spearman (tingkat signifikansi α=0.05). Aktivitas fisik dengan status gizi ditemukan bernilai P=0,520, pola makan dengan status gizi ditemukan bernilai P=0,013. Tak terdapat hubungan yang bermakna diantara aktivitas fisik dan status gizi di Sekolah Dasar Negeri 12 Dauh Puri namun ada korelasi signifikan diantara pola makan dan status gizi pada anak di SDN 12 Dauh Puri.
Co-Authors Dewa Ayu Agung Alit Suka Astini Komang Permata Indah Sari