Article Per Year (5 Year)
p-Index From 2021 - 2026
0.61
P-Index
This Author published in this journals
All Journal Journal of Medicine and Health Journal of Medicine and Health Jurnal Kesehatan Masyarakat
Sugiarto Puradisastra
Universitas Kristen Maranatha
Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

Published : 3 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 3 Documents
Search

 1 
THE INHIBITION EFFECT OF MORINGA (Moringa oleifera L.) LEAVES AND RED GINGER RHIZOME (Zingiber officinale Rosc.) PT. "P" ETHANOL EXTRACT ON ENHANCEMENT SERUM CREATININE LEVELS OF MALE WISTAR RATS DYSLIPIDEMIA MODEL Juliana Wijaya; Penny S Martioso; Sugiarto Puradisastra
Journal of Medicine and Health Vol 5 No 1 (2023)
Publisher : Universitas Kristen Maranatha

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.28932/jmh.v5i1.4528

Abstract

Elevation of serum creatinine levels is a biomarker of decreased kidney function. Dyslipidemia can decrease kidney function. Long-term consuming statins can increase creatinine levels. Moringa leaves (Moringa oleifera L.) and red ginger rhizomes (Zingiber officinale Rosc.) have antioxidant effects. Aim of study is to determine the inhibitory effect on increasing serum creatinine levels of concoction Moringa Leaves and Red Ginger Rhizome ethanol extract (CML-RGRE). True laboratory experimental study with completely randomized design was conducted on 30 male Wistar rat dyslipidemia models, induced by high-fat feeding (HFF)-Propylthiouracil (PTU) 0.01% for 21 days. Subjects were divided into six groups (n=5), Group I, II, III were treated CML-RGRE 135, 202.5, 270 mg/kg BW, IV dyslipidemia control, V Rosuvastatin 1.8 mg/kg BW, and VI fenofibrate 5.4 mg/kg BW, all still given HFF-PTU for 21 days. Serum creatinine levels (mg/dL) were measured 3 times, after acclimatization, created dyslipidemia models, and treatment using spectrophotometer, colorimetric kinetic methods. Data were analysed with paired t-test, ANOVA test, and Fischer's LSD, α = 0.05. All doses of CML-RGRE have effectively inhibited the increase serum creatinine levels (p < 0.01). Conclusion, Moringa Leaves and Red Ginger Rhizome ethanol extract effectively inhibited the increased serum creatinine levels of animal dyslipidemia models.
THE INHIBITION EFFECT OF MORINGA (Moringa oleifera L.) LEAVES AND RED GINGER RHIZOME (Zingiber officinale Rosc.) PT. "P" ETHANOL EXTRACT ON ENHANCEMENT SERUM CREATININE LEVELS OF MALE WISTAR RATS DYSLIPIDEMIA MODEL Juliana Wijaya; Penny S Martioso; Sugiarto Puradisastra
Journal of Medicine and Health Vol 5 No 1 (2023)
Publisher : Universitas Kristen Maranatha

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.28932/jmh.v5i1.4528

Abstract

Elevation of serum creatinine levels is a biomarker of decreased kidney function. Dyslipidemia can decrease kidney function. Long-term consuming statins can increase creatinine levels. Moringa leaves (Moringa oleifera L.) and red ginger rhizomes (Zingiber officinale Rosc.) have antioxidant effects. Aim of study is to determine the inhibitory effect on increasing serum creatinine levels of concoction Moringa Leaves and Red Ginger Rhizome ethanol extract (CML-RGRE). True laboratory experimental study with completely randomized design was conducted on 30 male Wistar rat dyslipidemia models, induced by high-fat feeding (HFF)-Propylthiouracil (PTU) 0.01% for 21 days. Subjects were divided into six groups (n=5), Group I, II, III were treated CML-RGRE 135, 202.5, 270 mg/kg BW, IV dyslipidemia control, V Rosuvastatin 1.8 mg/kg BW, and VI fenofibrate 5.4 mg/kg BW, all still given HFF-PTU for 21 days. Serum creatinine levels (mg/dL) were measured 3 times, after acclimatization, created dyslipidemia models, and treatment using spectrophotometer, colorimetric kinetic methods. Data were analysed with paired t-test, ANOVA test, and Fischer's LSD, α = 0.05. All doses of CML-RGRE have effectively inhibited the increase serum creatinine levels (p < 0.01). Conclusion, Moringa Leaves and Red Ginger Rhizome ethanol extract effectively inhibited the increased serum creatinine levels of animal dyslipidemia models.
A.galanga (L.)-Willd Rhizome and O.sanctum L. Leave Essential Oils as Culex sp. Larvicide Sugiarto Puradisastra; Regina Aurellia Limijaya; Angelica Rosa Septiana Hartono; Susy Tjahjani
Jurnal Kesehatan Masyarakat Vol. 20 No. 3 (2025)
Publisher : Universitas Negeri Semarang in collaboration with Ikatan Ahli Kesehatan Masyarakat Indonesia (IAKMI Tingkat Pusat) and Jejaring Nasional Pendidikan Kesehatan (JNPK)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/kemas.v20i3.3388

Abstract

Culex sp. can transmit diseases such as encephalitis and filariasis which is a public health problem because of elephantiasis, disability, and a neglected tropical disease. To prevent these diseases, the mosquitoes need to be eradicated and larvicides are considered to control them at their early stage. Temephos, a synthetic larvicide, could cause several disadvantage, such as potential toxicity against non-target organisms and easierto-develop mosquito resistance. Botanical sources from Indonesian spices i.e. galangal (Alpinia galanga (L.) Willd.) and basil (Ocimum sanctum L.) are potentially used as larvicide. This study aimed to explore the larvicidal effect of their essential oils compared against temephos against Culex sp. A true experimental study was done using several concentrations and replications of these essential oils in each container, consisting of 25 third instar of Culex sp larvae for 24 hours at room temperature according to WHO procedure. The percentage of dead larvae was analyzed by ANOVA/ Kruskal Wallis. The study showed that Alpinia galanga ( L.) Willd. and Ocimum sanctum L. essential oils had larvicide activity and their activity starting from 140 ppm and 400 ppm consecutively was the same as temephos 1 ppm.
Co-Authors Angelica Rosa Septiana Hartono Juliana Wijaya Penny S Martioso Regina Aurellia Limijaya Susy Tjahjani